Gene Information

Name : EC55989_0223 (EC55989_0223)
Accession : YP_002401352.1
Strain : Escherichia coli 55989
Genome accession: NC_011748
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 249467 - 252340 bp
Length : 2874 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor

DNA sequence :
TTGTGGTGGCGTTGTCGTGCTGGCGTTGTTTTACCTGTTCTATCTGTTGCGGCTGGACAGCCAGACGCAGGACATCCTGC
ACCAGCTAAACAAATTACTTCGATAAGGACGTTTATGATCCAGATTGATCTTCCCACGCTGGTAAAACGGCTGAACCTGT
TCTCCCGCCAGGCGCTGGAGATGGCCGCCTCTGAATGTATGAGTCAGCAGGCAGCGGAAATTACCGTCAGCCATGTGCTC
ATTCAGATGCTCGCCATGCCACGCAGTGACCTGCGGGTTATTACCCGCCAGGGCGATATTGGCATGGAAGAGTTGCGCCA
GGCGCTGACGGTAGAGAACTACACAACCGCCCGTTCTGCGGACAGCTACCCGGCGTTTTCCCCGATGCTGGTTGAGTGGC
TTAAAGAGGGCTGGCTGCTGGCGTCGGCTGAGATGCAGCACAGCGAACTGCGCGGCGGCGTGTTGCTGCTGGCCCTGCTG
CATTCGCCGCTGCGTTATATACCGCCTGCTGCCGCCCGGCTGTTGACCGGCATTAACCGTGACCGTCTGCAACAGGACTT
TGTGCAGTGGACACAGGAGTCGGCGGAATCAGTCGTGCCGGATGCAGACGGTAAAGGCGCAGGCACAATGACGGACGCCT
CTGACACCCTGCTTGCCCGCTATGCCAAAAACATGACCGCAGACGCCCGTAACGGCAGGCTTGACCCGGTACTGTGCCGC
GACCACGAAATCGACCTGATGATCGACATTCTCTGCCGCCGCCGTAAAAACAACCCGGTGGTGGTGGGCGAAGCGGGCGT
GGGCAAAAGCGCACTGATTGAAGGGCTGGCGCTGCGCATCGTGGCAGGCCAGGTGCCGGACAAGCTGAAAAACACCGATA
TCATGACCCTTGACTTGGGCGCATTGCAGGCCGGGGCGTCGGTGAAGGGTGAATTCGAAAAACGTTTCAAAGGGCTGATG
GCGGAGGTCATTTCCTCCCCGGTGCCGGTCATTCTGTTTATCGACGAAGCACATACCCTGATTGGCGCGGGCAACCAGCA
GGGCGGGCTGGATATCTCCAACCTGCTCAAACCGGCGCTGGCGCGCGGCGAGCTGAAAACCATCGCCGCCACCACCTGGA
GCGAGTACAAAAAATACTTCGAAAAAGATGCCGCCCTGTCGCGCCGCTTCCAGTTGGTGAAGGTCAGCGAACCCAACGCT
GCCGAAGCCACCATTATTCTGCGCGGTCTGTCGGCGGTCTATGAACAGTCTCACGGCGTGCTGATTGATGATGACGCCTT
GCAGGCCGCTGCGACATTAAGCGAGCGTTATCTCTCCGGGCGTCAGTTACCGGACAAAGCGATTGATGTGCTGGATACCG
CCTGCGCCCGTGTGGCCATCAACCTGTCGTCGCCGCCGAAGCAAATCTCGGCGCTGACCACTCTGAGCCACCAGCAGGAG
GCGGAAATTCGCCAGCTTGAGCGCGAGCTTCGCATCGGACTGCGTACCGACACATCACGGATGACCGAGGTGCTGGTGCA
GTATGATGAAACGCTGACGGCGCTGGATGAACTGGAAGCGGCCTGGCACCAGCAGCAGACGCTGGTCCGGGAGATTATTG
CGCTGCGCCAGCAGTTACTGGGCGTGGCAGAGGACGATGCGGCGCCGTTGCCGGACGCAGATACCGTGGAGGATACGCAG
CCAGAGTCAGAACAGGATAATACCGGTGCTAAACTGGCTGATGAAGCTGGCAGCGAACAGCCGGAAGAGACCGCAGAAAC
AGTTTCCCCGGTGCAGCGACTGGCACAGCTCACTGCCGAACTGGACGCCCTGCATAACGACCGGTTGCTGGTCTCCCCGC
ACGTCGATAAAAAACAGATTGCGGCGGTGATTGCCGAATGGACCGGCGTACCGCTTAACCGCCTGTCACAGAATGAGATG
TCGGTCATCACCGACCTGCCGGTATGGCTGGGTGACACCATCAAAGGCCAGGACCTGGCGATTGCCAGCCTGCATAAACA
CCTGCTGACTGCACGCGCCGACCTGCGTCGTCCGGGACGCCCACTCGGCGCGTTTCTGCTGGCCGGTCCCAGCGGCGTGG
GTAAAACCGAAACCGTCCTGCAACTGGCAGAACTGCTCTACGGCGGTCGCCAGTACCTGACCACCATCAATATGTCCGAG
TTCCAGGAAAAACACACCGTCTCGCGGCTGATTGGCTCCCCTCCGGGCTATGTCGGCTATGGCGAAGGCGGCGTACTGAC
CGAAGCGATTCGCCAGAAACCGTACTCGGTGGTGCTGCTTGATGAAGTGGAAAAAGCGCACCCGGATGTCCTCAACCTGT
TCTACCAGGCGTTCGACAAGGGCGAGATGGCAGACGGCGAAGGCCGACTGATTGACTGTAAGAATATCGTTTTCTTCCTC
ACCTCCAACCTTGGTTACCAGGTGATTGTTGAACACGCGGATGACCCGGAAACCATGCAGGAAGTGCTGTATCCGGTGCT
GGCGGACTTCTTTAAACCAGCCCTGCTGGCGCGTATGGAAGTGGTGCCGTACCTGCCTCTGTCGAAAGAGACGCTCACCA
CCATTATCGACGGGAAACTGGCCCGCCTGGATAACGTGCTGCGCAGCCGCTTTGATGCGGACGTGATTATTGAGTCGGAA
GTGACGGACGAGATCATGAGCCGCGTCACCCGCGCGGAAAACGGCGCAAGGATGCTGGAGTCCGTCATTGACGGCGACAT
GCTGCCCCCGCTCTCGCTGCTGCTGTTGCAGAAAATGGCGGCCAACACGGCGATTGCCCGCATCCGCCTGTCGGCGGCAG
ACGGCGCGTTCACGGCAGACGTGGAAGATGCTCTGGACGACGAGTCTGTCACAGAGGATGAAACGGATTTATGA

Protein sequence :
MWWRCRAGVVLPVLSVAAGQPDAGHPAPAKQITSIRTFMIQIDLPTLVKRLNLFSRQALEMAASECMSQQAAEITVSHVL
IQMLAMPRSDLRVITRQGDIGMEELRQALTVENYTTARSADSYPAFSPMLVEWLKEGWLLASAEMQHSELRGGVLLLALL
HSPLRYIPPAAARLLTGINRDRLQQDFVQWTQESAESVVPDADGKGAGTMTDASDTLLARYAKNMTADARNGRLDPVLCR
DHEIDLMIDILCRRRKNNPVVVGEAGVGKSALIEGLALRIVAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEKRFKGLM
AEVISSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKPALARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEPNA
AEATIILRGLSAVYEQSHGVLIDDDALQAAATLSERYLSGRQLPDKAIDVLDTACARVAINLSSPPKQISALTTLSHQQE
AEIRQLERELRIGLRTDTSRMTEVLVQYDETLTALDELEAAWHQQQTLVREIIALRQQLLGVAEDDAAPLPDADTVEDTQ
PESEQDNTGAKLADEAGSEQPEETAETVSPVQRLAQLTAELDALHNDRLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEM
SVITDLPVWLGDTIKGQDLAIASLHKHLLTARADLRRPGRPLGAFLLAGPSGVGKTETVLQLAELLYGGRQYLTTINMSE
FQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQAFDKGEMADGEGRLIDCKNIVFFL
TSNLGYQVIVEHADDPETMQEVLYPVLADFFKPALLARMEVVPYLPLSKETLTTIIDGKLARLDNVLRSRFDADVIIESE
VTDEIMSRVTRAENGARMLESVIDGDMLPPLSLLLLQKMAANTAIARIRLSAADGAFTADVEDALDDESVTEDETDL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 0.0 92
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 0.0 92

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EC55989_0223 YP_002401352.1 ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity VFG2084 Protein 0.0 57
EC55989_0223 YP_002401352.1 ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity VFG2076 Protein 1e-136 42