Gene Information

Name : int (ECED1_4922)
Accession : YP_002400684.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Unknown
Product : Prophage integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 4879739 - 4881001 bp
Length : 1263 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin

DNA sequence : 
ATGGCACTGACTGACGCAAAAATCCGGGCTGCAAAGCCCACTGACAAGGCTTATAAACTCACTGACGGGGCTGGCATGTT
CCTGCTGGTACATCCTAATGGCTCCCGTTACTGGCGTCTCCGTTATCGTATTCTGGGTAAGGAGAAGACTCTGGCACTTG
GTGTGTATCCAGAAGTTTCTCTCTCCGAAGCTCGTACAAAACGGGATGAGGCCCGAAAACTGATTTCGGAGGGGGTTGAC
CCTTGCGAACAGAAAAGAGCTAAAAAAGTAGTCCCTGATTTACAGCTCTCTTTTGAACATATTGCGCGACGCTGGCATGC
CAGTAATAAACAATGGGCACAATCACACAGCGATAAAGTACTCAAAAGCCTCGAGACTCACGTTTTCCCCTTTATCGGCA
ACCGGGATATCACAACACTCAATACCCCGGATCTGCTTATCCCTGTTCGTGCTGCAGAAGCTAAACAAATTTATGAAATC
GCCAGTCGTCTGCAGCAAAGAATATCTGCCGTAATGCGTTATGCCGTACAGTCTGGCATCATCAGATATAATCCTGCTCT
GGATATGGCTGGCGCATTGACTACGGTAAAACGCCAGCATCGCCCCGCTCTTGATCTTTCTCGCCTGCCTGAACTTTTGT
CGCGTATTGGCAGTTACAAAGGGCAACCTGTCACCCAGCTTGCCGTTATGCTGAATTTACTGGTTTTTATTCGTTCCAAT
GAACTCAGATACGCCCGCTGGTCTGAAATTGATATTGACAATGCCATGTGGACTATTCCAGCCGAACGCGAACCCCTGCC
AGGCGTAAAATTCTCACACCGGGGCTCCAAGATGCGAACACCACATCTTGTGCCACTCAGCAAACAGGCTGTAGCCATAC
TGACAGAACTACAGACATGGGCTGGTGAAAATGGTCTGATCTTTACGGGAGCACATGACCCGCGTAAACCAATCAGTGAA
AATACTGTAAATAAAGCCCTGAGGGTGATGGGGTATGACACAACCCAGGATGTCTGTGGCCATGGATTCCGGGCGATGGC
GTGCAGTGCATTGATTGAATCAGGTTTGTGGTCCCGCGATGCTGTGGAACGTCAGATGAGCCATCAGGAGCGTAATGGTG
TACGTGCTGCGTATATCCATAAAGCAGAACATCTGGAAGAACGTCGACTGATGCTACAGTGGTGGGCAGATTTTCTGGAT
GCGAACAGAGATAAGGGTATCAGCCCGTTTGAATATGCAAAGATTAACAATCCATTAAAATAG

Protein sequence : 
MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRILGKEKTLALGVYPEVSLSEARTKRDEARKLISEGVD
PCEQKRAKKVVPDLQLSFEHIARRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLNTPDLLIPVRAAEAKQIYEI
ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALDLSRLPELLSRIGSYKGQPVTQLAVMLNLLVFIRSN
ELRYARWSEIDIDNAMWTIPAEREPLPGVKFSHRGSKMRTPHLVPLSKQAVAILTELQTWAGENGLIFTGAHDPRKPISE
NTVNKALRVMGYDTTQDVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLMLQWWADFLD
ANRDKGISPFEYAKINNPLK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 0.0 99
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 0.0 99
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 0.0 99
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 0.0 99
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 0.0 99
int AAL51028.1 CP4-like integrase Not tested LEE Protein 0.0 99
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 0.0 99
int-phe AAL60261.1 Int-phe Not tested LEE Protein 0.0 99
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 0.0 99
int CAC81896.1 integrase Not tested LEE II Protein 0.0 99
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 0.0 98
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 0.0 98
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 0.0 98
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 0.0 98
int AAL51003.1 CP4-like integrase Not tested LEE Protein 0.0 98
int AAK16198.1 Int Not tested PAI-I AL862 Protein 0.0 98
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 0.0 98
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 0.0 98
int AAK00456.1 Int Not tested SHI-1 Protein 0.0 97
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 0.0 97
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 0.0 97
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 1e-137 67
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 2e-129 61
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 2e-129 61
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 2e-77 55
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 2e-115 55
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 2e-115 55
int YP_002346908.1 integrase Not tested HPI Protein 2e-109 55
int CAA08754.1 integrase Not tested HPI Protein 5e-110 55
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 2e-109 55
int CAB59974.1 integrase Not tested HPI Protein 1e-110 55
int2 NP_993013.1 integrase Not tested HPI Protein 2e-109 55
int CAA21384.1 - Not tested HPI Protein 2e-109 55
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 4e-116 54
unnamed AAD17660.1 unknown Not tested HPI Protein 4e-107 54
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 7e-90 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 6e-103 51
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-84 42
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 3e-76 42
int AAD44730.1 Int Not tested SHI-2 Protein 1e-83 42
int CAC39282.1 integrase Not tested LPA Protein 3e-84 42
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 8e-75 41
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 6e-82 41
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 6e-82 41
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 4e-82 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
int YP_002400684.1 Prophage integrase VFG0626 Protein 0.0 98
int YP_002400684.1 Prophage integrase VFG1693 Protein 0.0 97
int YP_002400684.1 Prophage integrase VFG1536 Protein 6e-138 67
int YP_002400684.1 Prophage integrase VFG0598 Protein 3e-82 41