Gene Information

Name : iucB (ECED1_4904)
Accession : YP_002400669.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Virulence
Product : aerobactin siderophore biosynthesis N(6)-hydroxylysine acetylase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1670
EC number : -
Position : 4863960 - 4864907 bp
Length : 948 bp
Strand : -
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme

DNA sequence :
ATGTCTGAGGCAAACATTATTCACAGCAGATATGGACTGCGCTGTGAAAAACTCGACAAGCCCCTGAATCTTGGCTGGGG
ACTGGACAATAGCGCGGTGTTGCACTGTTCCGGGGAGCTGCCGACAGGGTGGCTGTGCGATGCGCTGGATCAGATATTTA
TCGCCGCACCACAACTGTCAGCAGTGGCTCTCCCCTGGGCCGAATGGCGTGAGGAGCCACAGGCGCTGACGCTTTTTGGG
CAGGTAAAAAGCGACATTATCCATCGTACTGCCTTCTGGCAGTTACCGTTATGGTTGAGTTCACCGGCAAACCGGGCCTC
CGGTGAAATGGTTTTTGATGCAGAGCGTGAGATTTATTTCCCGCAGCGCCCACCCCGTCCACAGGGTGAGGTTTACCGCC
GTTACGATCCACGTATTCGCAGGATGCTGAGTTTCCGCATTGCCGATCCCGTTTCTGATGCAGAACGTTTCACCCGCTGG
ATGAATGATCCGCGCGTTGAGTATTTCTGGGAGCAAAGTGGCTCACTGGAGGTACAGACCGCCTATCTGGAGCGCCAGCT
CACCGGTAAACATGCATTCCCGCTGATTGGGTGCTTCGACGATCGGCCATTCAGCTATTTCGAAATCTACTGGGCGGCGG
AAGACCGCATTGGTCGTCACTATTCGTGGCAGCCCTTTGACCGTGGCCTGCATCTGCTGGTTGGTGAACAGCAATGGCGC
GGGGCCCACTATGTGCAAAGCTGGCTGCGCGGGCTGACACATTACCTGCTGCTGGATGAGCCCCGTACGCAGCGCACAGT
ACTGGAGCCACGCACCGATAACCAGCGCCTGTTCCGCCATCTTGAGCCTGCGGGATACCGGACAATTAAAGAGTTCGACT
TCCCACATAAGCGCTCGCGCATGGTGATGGCGGATCGTCATCACTTCTTCACGGAGGTCGGTCTGTAA

Protein sequence :
MSEANIIHSRYGLRCEKLDKPLNLGWGLDNSAVLHCSGELPTGWLCDALDQIFIAAPQLSAVALPWAEWREEPQALTLFG
QVKSDIIHRTAFWQLPLWLSSPANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRW
MNDPRVEYFWEQSGSLEVQTAYLERQLTGKHAFPLIGCFDDRPFSYFEIYWAAEDRIGRHYSWQPFDRGLHLLVGEQQWR
GAHYVQSWLRGLTHYLLLDEPRTQRTVLEPRTDNQRLFRHLEPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucB YP_002414045.1 aerobactin siderophore biosynthesis protein, N(6)-hydroxylysine acetylase Virulence Not named Protein 1e-146 99
iucB NP_839222.1 siderophore biosynthesis protein Virulence SHI-2 Protein 1e-147 99
iucB NP_709455.1 siderophore biosynthesis protein Virulence SHI-2 Protein 1e-147 99
iucB AAK71632.1 IucB Virulence SHI-3 Protein 8e-148 99
iucB AAD44747.1 IucB Virulence SHI-2 Protein 7e-148 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucB YP_002400669.1 aerobactin siderophore biosynthesis N(6)-hydroxylysine acetylase VFG0939 Protein 5e-147 99
iucB YP_002400669.1 aerobactin siderophore biosynthesis N(6)-hydroxylysine acetylase VFG0616 Protein 4e-148 99
iucB YP_002400669.1 aerobactin siderophore biosynthesis N(6)-hydroxylysine acetylase VFG1082 Protein 4e-148 99