Gene Information

Name : iucC (ECED1_4903)
Accession : YP_002400668.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Virulence
Product : Aerobactin siderophore biosynthesis protein
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG4264
EC number : -
Position : 4862218 - 4863960 bp
Length : 1743 bp
Strand : -
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 3087960; Product type e : enzyme

DNA sequence :
ATGAATCACAAGGACTGGGATTTTGTTAACCGTCGGCTGGTGGCAAAAATGTTGTCTGAGATGGAGTATGAGCAGGTTTT
CCACGCGGAATCTCAGGGCGATGACCACTACTGCATTAACCTGCCGGGAGCACAATGGCGCTTCATCGCTGAACGTGGTA
TCTGGGGCTGGCTGTGGATTGATGCCCAAACGTTGCGCTGCACGGACGAACCAGTACTGGCGCAGACGCTGCTGATGCAG
CTAAAGCCGGTGCTGTCAATGAGTGATGCCACTGTTGCAGAGCATATGCAGGATTTGTATGCCACGCTACTGGGCGACCT
GCAACTGCTGAAGGCCCGTCGCGGACTGAGTGCCAGTGACCTGATTAATCTTGATGCCGATCGTCTGCAATGCCTGCTGA
GCGGTCATCCTAAATTCGTTTTTAATAAAGGTCGCCGTGGCTGGGGCAAAGAGGCGCTGGAACGATATGCGCCAGAGTAT
ACCAACACCTTCAGACTGCACTGGCTGGCGGTAAAACGTGAACATATGATCTGGCGCTGCGATAACGATCTGGATATTCA
GCAGTTGTTGACTGCCGCAATGGATCCGCAGGAGTTTACACGCTTCAGTCAGGTCTGGCAGGAAAACGGGCTGGATCACA
ACTGGCTGCCGCTGCCGGTACATCCGTGGCAGTGGCAGCAAAAAATCGCCACAGACTTCATCGCTGATTTTGCCGAAGGC
AGGATGGTGTCTCTCGGCGAGTTTGGCGACCAGTGGCTCGCCCAGCAGTCGCTGCGTACCCTGACCAACGCCAGCCGCCG
GGGAGGGCTGGATATCAAGCTGCCGCTGACCATCTACAACACCTCATGCTACCGGGGGATCCCTGGCAGATATATCGCTG
CCGGACCACTGGCTTCACGCTGGCTGCAACAGGTTTTTGCGACCGACGCCACCCTGGTGCAAAGCGGCGCAGTGATCCTT
GGTGAACCGGCTGCAGGCTATGTGTCCCATGAAGGCTATGCCGCGCTTGCCCGGGCTCCCTATCGCTACCAGGAAATGCT
TGGTGTTATCTGGCGGGAGAATCCGTGCCGCTGGCTGAAACCGGATGAAAGTCCTGTTCTGATGGCAACACTGATGGAGT
GCGACGAAAACAATCAGCCGCTGGCAGGCGCATATATCGACCGCTCCGGACTGGACGCTGAAACCTGGCTTACGCAATTG
TTCCGGGTGGTTGTGGTTCCGCTGTATCACCTGCTTTGCCGCTACGGTGTCGCGCTTATTGCACACGGACAAAATATAAC
GCTCGCCATGAAAGAGGGGGTACCACAGCGTGTTCTGCTGAAAGACTTCCAGGGCGATATGCGGCTGGTGAAAGAAGCGT
TTCCCGAAATGGACTCTTTGCCTCAGGAGGTGCGTGATGTCACATCCCGTCTGAGTGCGGACTACTTAATCCATGATTTG
CAGACGGGCCACTTCGTGACAGTACTGCGTTTTATTTCGCCACTGATGGTTCGTCTTGGCGTACCTGAAAGGCGATTTTA
TCAACTGCTGGCAGCAGTGTTGAGTGATTACATGAACAAACATCCACAAATGGCAGAGCGTTTTGCGCTTTTCTCACTCT
TCAGGCCACAAATCATTCGCGTGGTGCTGAACCCGGTAAAACTGACCTGGCCGGACCTGGATGGCGGCAGTCGCATGCTG
CCGAATTACCTTGAGAATCTGCAAAATCCGCTGTGGCTGGTAACTCAGGAATATGAATCATGA

Protein sequence :
MNHKDWDFVNRRLVAKMLSEMEYEQVFHAESQGDDHYCINLPGAQWRFIAERGIWGWLWIDAQTLRCTDEPVLAQTLLMQ
LKPVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLDADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEY
TNTFRLHWLAVKREHMIWRCDNDLDIQQLLTAAMDPQEFTRFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG
RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVIL
GEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQL
FRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEAFPEMDSLPQEVRDVTSRLSADYLIHDL
QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMNKHPQMAERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRML
PNYLENLQNPLWLVTQEYES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucC NP_839221.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 100
iucC NP_709456.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 100
iucC YP_002414044.1 Aerobactin siderophore biosynthesis protein Virulence Not named Protein 0.0 99
iucC AAD44748.1 IucC Virulence SHI-2 Protein 0.0 99
iucC AAK71633.1 IucC Virulence SHI-3 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iucC YP_002400668.1 Aerobactin siderophore biosynthesis protein VFG0617 Protein 0.0 100
iucC YP_002400668.1 Aerobactin siderophore biosynthesis protein VFG0938 Protein 0.0 99
iucC YP_002400668.1 Aerobactin siderophore biosynthesis protein VFG1083 Protein 0.0 99