Gene Information

Name : thiC (ECED1_4701)
Accession : YP_002400487.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4653514 - 4655409 bp
Length : 1896 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTGCAACAAAACTGACCCGCCGCGAACAACGCGCCCAGGCCCAACATTTTATCGACACCCTGGAAGGCTCCGCCTT
TCCCAACTCAAAACGCATTTACATCACTGGCACACACCCCGGCGTACGCGTGCCGATGCGTGAGATTCAGCTTAGCCCGA
CGCTAATTGGCGGCAGCAAAGAACAGCCGCAGTACGAAGAAAACGAAGCGATTCCGGTCTACGACACCTCCGGCCCGTAT
GGCGATCCGCAGATTGCCATTAACGTGCAGCAAGGGCTGGCAAAACTACGCCAGCCGTGGATCGATGCGCGCGGCGATAC
CGAAGAACTTACCGTGCGCAGTTCCGATTACACAAAAGCGCGGCTGGCAGATGATGGCCTCGACGAGCTGCGTTTTAGCG
GCGTATTAACCCCAAAACGCGCCAAAGCAGGCCACCGCGTCACACAACTGCACTACGCCCGCAAGGGTATCATCACGCCA
GAAATGGAATTCATCGCCATTCGCGAGAATATGGGTCGCGAGCGCATACGTAGCGAAGTTTTACGCCACCAGCATCCGGG
AATGAGCTTTGGCGCACGTCTGCCGGAAAATATCACTGCGGAATTTGTCCGTGATGAAGTTGCTGCCGGACGTGCGATTA
TCCCGGCCAACATTAATCATCCGGAATCGGAGCCGATGATTATTGGCCGTAACTTCCTGGTAAAAGTTAACGCCAATATC
GGCAACTCAGCGGTCACTTCTTCCATCGAAGAAGAAGTGGAAAAACTGGTATGGTCCACACGCTGGGGAGCGGATACCGT
GATGGATCTTTCCACTGGTCGCTATATTCACGAAACCCGCGAGTGGATTTTGCGTAACAGCCCGGTGCCGATCGGTACAG
TGCCGATCTACCAGGCACTGGAGAAGGTGAACGGGATCGCTGAAGATCTTACCTGGGAAGTCTTCCGCGACACCCTGCTG
GAACAAGCCGAGCAAGGTGTGGATTACTTCACGATCCATGCGGGGGTGCTGCTGCGCTACGTGCCGATGACCGCGAAACG
CCTGACCGGTATCGTCTCTCGCGGCGGTTCGATTATGGCGAAATGGTGCCTCTCCCATCATCAGGAAAATTTCCTCTATC
AACACTTCCGCGAAATTTGTGAAATCTGTGCTGCTTATGACGTTTCGCTATCGCTGGGCGACGGCCTGCGCCCCGGTTCT
ATTCAGGACGCCAACGATGAAGCACAGTTTGCCGAGCTGCATACGCTGGGTGAACTGACTAAAATCGCCTGGGAATATGA
CGTACAGGTGATGATTGAAGGCCCAGGCCACGTGCCGATGCAGATGATTCGCCGCAATATGACCGAGGAGTTAGAGCACT
GCCACGAAGCGCCGTTTTACACTCTGGGGCCGCTAACTACCGATATCGCGCCGGGCTATGACCACTTCACGTCAGGGATT
GGCGCGGCGATGATTGGCTGGTTTGGTTGTGCAATGCTCTGCTACGTAACGCCGAAAGAGCATCTGGGCCTGCCAAATAA
AGAAGATGTTAAACAGGGGCTTATCACCTATAAGATTGCCGCTCACGCCGCCGACCTGGCGAAAGGGCATCCGGGCGCGC
AAATTCGCGATAACGCCATGTCGAAAGCCCGCTTCGAATTTCGCTGGGAAGACCAGTTTAATCTGGCCCTCGACCCGTTT
ACTGCCCGCGCTTATCACGATGAAACCCTGTCGCAAGAGTCCGGTAAAGTCGCCCATTTTTGCTCCATGTGTGGACCGAA
ATTCTGCTCGATGAAAATCAGCCAGGAAGTGCGTGATTACGCCGCCGCGCAAACCATTGAAGTGGGAATGGCGGATATGT
CGGAGAACTTCCGCGCCAGAGGCGGAGAAATCTACCTGCGTAAGGAGGAAGCGTGA

Protein sequence :
MSATKLTRREQRAQAQHFIDTLEGSAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPY
GDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGHRVTQLHYARKGIITP
EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEVFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLSQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 69
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 69
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 68