Gene Information

Name : rph (ECED1_4327)
Accession : YP_002400139.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 4249998 - 4250738 bp
Length : 741 bp
Strand : -
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
TTGTTTCAAGCCGGAGATTTCAATATGCGTCCAGCAGGCCGTAGCAATAATCAGGTGCGTCCCGTTACCCTGACTCGTAA
CTATACAAAACATGCAGAAGGCTCGGTGCTGGTCGAATTTGGCGATACCAAAGTATTGTGTACCGCCTCTATTGAAGAAG
GCGTGCCGCGCTTCCTGAAAGGTCAGGGCCAGGGTTGGATCACCGCAGAGTACGGTATGCTGCCACGTTCTACCCATACC
CGTAACGCGCGTGAAGCGGCGAAAGGTAAGCAGGGTGGACGCACAATGGAAATCCAGCGTCTGATCGCCCGTGCTCTTCG
CGCGGCAGTAGATTTGAAAGCACTGGGTGAGTTCACCATTACGCTGGACTGCGACGTGCTTCAGGCTGATGGTGGCACGC
GTACCGCTTCGATTACGGGTGCCTGCGTGGCGCTGGCAGATGCGCTACAGAAGCTGGTGGAAAACGGCAAGCTGAAAACT
AATCCAATGAAAGGGATGGTAGCCGCGGTCTCTGTCGGGATTGTGAACGGTGAAGCGGTTTGCGATCTGGAATATGTTGA
AGACTCTGCCGCAGAGACCGACATGAACGTAGTGATGACCGAAGACGGGCGTATCATTGAAGTGCAGGGGACGGCAGAAG
GCGAACCGTTCACCCACGAAGAGTTACTCACCTTGTTGGCGCTGGCCCGAGGGGGAATCGAATCCATTGTAGCGACGCAG
AAGGCGGCGCTGGCAAACTGA

Protein sequence :
MFQAGDFNMRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHT
RNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKT
NPMKGMVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLLALARGGIESIVATQ
KAALAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 9e-54 58