Gene Information

Name : lpfC (ECED1_4229)
Accession : YP_002400047.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Virulence
Product : outer membrane usher protein lpfC
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 4149253 - 4151784 bp
Length : 2532 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14977923; Product type m : membrane component

DNA sequence :
ATGCATTGGATGCATTTACCTCTTGATCACTACAGAGCGCATTTTTCTTTCTCACTGTTGGCATTAACTATTGCCAGCGC
GTTACCTGCGTACGGCGGAAAATTCAACCCTAAATTTCTTGAAAATGTTCAGGGTATTGATCAACACGTCGATTTGTCAG
TTTACGACTTTCCTGTCGGCCAGCAAATACCCGGTAAATATCGGGTATTTGTGTTTGTAAACGAAGAAAAAATGGCTTCC
CGGACGCTGGATTTTAGTACTGCCAGCGAAGCACAACGCAAAGCCAGCGGCGAGTCGCTTATGCCTTGCCTTAGCCGTGT
TCAACTGGAAGAAATGGGCGTGCGCGTCGACAGCTTTCCGGCACTGAAGATATTGCCACCGGAAGCCTGCGTAGCGTTTG
ATGAAATCATTCCCCAGGCCACCAGTCGTTTTGATTTTAATACTCAGACGTTGCATCTTACCTTTCCACAGGCAGCAATG
ATGATGACCGCTCGTGGCACGGTTGATCCTTCTCGCTGGGACGAAGGAATACCTGCGCTGTTACTGGACTACAGCTTTAG
TGGCAGCAATGGTCGCAACGAAGGTTCCGGTTCATCTCCAGATTCGACCAGTGACAGTTATTACCTGAACCTGCGCAGCG
GTTTGAACGTGGGGCCGTGGCGTTTACGTAATAACAGTATCTGGAACCGTACCGATGGCAAAAATCAATGGGATAACGTT
GGTACATCGTTAAACCGGGCGATTATTCCACTCAAGTCACAGATAACATTGGGTGATACCGCCACGCCTGGCGAGATTTT
TGATAGCGTACAAATGCGCGGGGCATTATTGGCATCCGACGATGAAATGTTGCCGGATAGCCAGCGTGGCTTTGCTCCGG
TGGTGCGTGGCATCGCCAAAAGTAACGCTGAAGTGAGTATCGAACAGAACGGATATGTTATTTATCGTACCTTTGTTCAG
CCGGGCGCATTTGAGATTAACGATCTCTACGCAACCTCCGGCAGCGGTGACTTGACGGTGATCATTAAAGAATCTGACGG
AAGTGAACAACGTTTTATTCAACCATTTTCGGCAGTGGCGATTTTCCAGCGTGAAGGGTATCTGAAATACAGCCTTGCTG
CCGGTGAGTATCGTGCCGGTAATTACGACAGCGGTAAACCGCGATTCGGGCAATTTACTGCCATGTACGGCTTGCCGTGG
GGAATGACCGCCTATGGTGGTGCGTTGCTATCGGCAGACTACAACGCTTTAGCTCTGGGGCTGGGGAAAAACTTCGGCAC
CATTGGTGCGGTATCGGTGGATGTCACCCAGGCGAAAAGTCAGTTACGCAACAATGAAAAAGATGAAGGGCAGTCTTATC
GTTTCCTCTATTCGAAAAGTTTTGAGGGCGGTACCGACCTGCGTCTGTTGGGCTACAAGTACTCAACCAGCGGTTATTAC
ACCTTCCAGGAAGCGACCGATGTCCGTAGTGACGCCGACAGTGACTATCGGCGTTATCATAAGCGCAGCCAGATACAAGG
TAACATCACTCAGCAACTGGGAGACTACGGTTCTGTTTACTTCAATATGACGCAGCAGGATTACTGGAACGTTGATGGTA
AGGAGAACTCCTTAAGCGCTGGTTATCACGGTCATATTGGTCGTGTGAATTACAGTATCGCCTATACCTGGACGAGAAGC
CCTGAATGGGATGAAGACGATCGACTGTGGTCATTTAGCCTCTCAATACCGCTGGGTGGCGCATGGGGCAGTTATCGTAT
GACCACCGACCAGAACGGCAAGACGTCACAACAGGCCTCTGTCAGCGGCACATTACTGGAAGATCGTAACTTGAACTATA
ACGTTCAGCAGGGTTATACCAGTAATGGGGTTGGCAACAGTGGTAGTGTCAACATGGGTTATATGGGAGGTTCTGGCAAC
ATTGACGTGGGTTATAACTATTCCAAAGATAACCAACAAGTTAACTATGGTGTGCGTGGTGGAGTCATTGTTCACAGTGA
AGGTATCACTCTCTCGCAACCCTTGGGTGAAAGTCTGGCAATTGTTTCTGCGCCGGGTGCGCGTGGTGGACATGTAGTAA
ATAGCAGCGGCGTTGAAGTTGACTGGATGGGCAACGCAGTGGTGCCGTATCTCACGCCATATCGTGAAACCATTGTGGAA
TTGCGCAGCGACACGTTAGGGCAAAACGTTGAATTACAGGAAGCGTTTCAGAAAGTCGTTCCAACGCGTGGGGCGATAGT
CCGTTCCCGCTTTGATACGCGTGTCGGTTATCGTGTGCTGATGAGTTTGAAACGGGCGAATGGCAACGCAGTACCGTTTG
GTGCTACCGCAGCGTTAAGTGATGAGAGCAAACCTGCCAGCAGCATTGTGGGTGAAGAAGGACAGCTTTATATCAGCGGG
ATGCCAGAAGAGGGCGAATTGCAGGTGAGCTGGGGGCACGAGCAGGCGCAACGTTGCCGCGTGCCATTCCGCTTGCCAGA
GAAAAAGGATAATTCGGGTATCGTGATGGTTAATGCGGTATGCGATAAATAA

Protein sequence :
MHWMHLPLDHYRAHFSFSLLALTIASALPAYGGKFNPKFLENVQGIDQHVDLSVYDFPVGQQIPGKYRVFVFVNEEKMAS
RTLDFSTASEAQRKASGESLMPCLSRVQLEEMGVRVDSFPALKILPPEACVAFDEIIPQATSRFDFNTQTLHLTFPQAAM
MMTARGTVDPSRWDEGIPALLLDYSFSGSNGRNEGSGSSPDSTSDSYYLNLRSGLNVGPWRLRNNSIWNRTDGKNQWDNV
GTSLNRAIIPLKSQITLGDTATPGEIFDSVQMRGALLASDDEMLPDSQRGFAPVVRGIAKSNAEVSIEQNGYVIYRTFVQ
PGAFEINDLYATSGSGDLTVIIKESDGSEQRFIQPFSAVAIFQREGYLKYSLAAGEYRAGNYDSGKPRFGQFTAMYGLPW
GMTAYGGALLSADYNALALGLGKNFGTIGAVSVDVTQAKSQLRNNEKDEGQSYRFLYSKSFEGGTDLRLLGYKYSTSGYY
TFQEATDVRSDADSDYRRYHKRSQIQGNITQQLGDYGSVYFNMTQQDYWNVDGKENSLSAGYHGHIGRVNYSIAYTWTRS
PEWDEDDRLWSFSLSIPLGGAWGSYRMTTDQNGKTSQQASVSGTLLEDRNLNYNVQQGYTSNGVGNSGSVNMGYMGGSGN
IDVGYNYSKDNQQVNYGVRGGVIVHSEGITLSQPLGESLAIVSAPGARGGHVVNSSGVEVDWMGNAVVPYLTPYRETIVE
LRSDTLGQNVELQEAFQKVVPTRGAIVRSRFDTRVGYRVLMSLKRANGNAVPFGATAALSDESKPASSIVGEEGQLYISG
MPEEGELQVSWGHEQAQRCRVPFRLPEKKDNSGIVMVNAVCDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 2e-157 44
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 3e-158 42
lpfC YP_006098365.1 fimbrial outer membrane usher protein Not tested Tn2411 Protein 2e-137 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lpfC YP_002400047.1 outer membrane usher protein lpfC VFG0454 Protein 0.0 74
lpfC YP_002400047.1 outer membrane usher protein lpfC VFG0876 Protein 3e-162 44
lpfC YP_002400047.1 outer membrane usher protein lpfC VFG1645 Protein 2e-158 42
lpfC YP_002400047.1 outer membrane usher protein lpfC VFG0446 Protein 7e-148 41
lpfC YP_002400047.1 outer membrane usher protein lpfC VFG0912 Protein 3e-158 41