Gene Information

Name : kpsC (ECED1_3597)
Accession : YP_002399452.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Virulence
Product : Capsule polysaccharide export protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 3516286 - 3518313 bp
Length : 2028 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 8397187, 8326861; Product type t : transporter

DNA sequence :
ATGATTGGCATTTACTCGCCTGGCATCTGGCGTATTCCGCATCTGGAGAAATTTCTGGCGCAACCGTGCCAGAAACTTTC
TCTGCTGCGCCCTGTTCCGCAAGAAGTTGATGCTATCGCCGTGTGGGGACATCGTCCCAGCGCGGCGAAACCAGTCGCCA
TCGCCAAAGCAGCGGGAAAACCCGTCATTCGTCTGGAAGATGGATTTGTGCGTTCGCTGGATCTTGGCGTCAATGGCGAG
CCGCCGCTTTCTCTGGTGGTGGATGATTGTGGCATTTACTACGATGCCAGCAAGCCTTCAGCACTGGAGAAACTGGTACA
GGATAAAGCCGGAAATACAGCTCTGATAAGCCAGGCCAGAGAAGCGATGCACACCATCGTGACCGGGGATTTGTCGAAAT
ATAACCTGGCACCTGCGTTTGTGGCTGATGAGTCAGAACGTGCAGACATCGTTCTGGTTGTCGATCAGACATTTAATGAT
ATGTCAGTGACGTATGGCAATGCTGGCCCGCATGAGTTTGCTGCCATGCTGGAAGCCGCGATGGCGGAAAATCCTCAAGC
CGAAATTTGGGTGAAGGTGCACCCAGATGTACTGGAAGGAAAGAAAACAGGTTATTTCGCTGATCTGCGTGCCACGCAAC
GAGTACGTTTGATTGCCGAGAATGTCAGCCCGCAGTCGCTATTGCGACACATTTCCCGGGTTTACGTCGTGACCTCCCAA
TACGGCTTTGAAGCCTTGCTGGCAGGAAAACCAGTAACATGTTTCGGCCAGCCCTGGTATGCAGGCTGGGGCTTAACCGA
CGATCGCCATCCGCAGTCTGCTTTGTTATCTGCCCGACGCGGTTCTGCCACGCTGGAAGAACTTTTTGCCGCAGCATACC
TGCGTTACTGTCGCTATATCGATCCGCAAACGGGAGAAGTAAGCGATCTATTTACCGTGCTGCAATGGCTGCAATTACAA
CGTCGACATCTGCAACAGCGTGATGGTTATTTATGGGCGCCAGGCTTAACGCTGTGGAAGTCAGCGATCCTGAAACCTTT
CTTGCAAACGGCAACAAACCGGCTGAGTTTTTCACGTCGCTGTACTGCGGCGAGCGCCTGCGTGGTATGGGGTGTAAAGG
GAGAACAGCAATGGCGAGCCGAAGCGCAGCGAAAATCACTGCCGTTATGGCGAATGGAAGATGGTTTTCTGCGTTCATCC
GGACTTGGCTCTGACCTTTTGCCGCCGCTATCGTTGGTCCTGGATAAACGCGGGATCTACTATGACGCCACGCGCCCCTG
CGACCTGGAAGTGCTGCTTAATCACAGCCAGTTAACGCTGGCGCAGCAGATGCGAGCTGAAAAATTACGCCAGCGACTGG
TTGAAAGCAAACTGAGCAAATACAACCTGGGGGCTGATTTCTCTCTGCCAGCCGAAGCCAAAGGTAAAAAAGTTATCCTG
GTGCCGGGTCAGGTAGAAGACGATGCCTCAATTAAAACAGGCACTGTCTCGATTAAGAGCAACCTTGAGTTATTACGCAC
AGTACGCGAGCGCAATCCGCACGCTTACATTATTTATAAACCGCACCCGGATGTACTGGTGGGGAATCGCAAGGGCAATA
TTCCGGCAGAACTAATTGCTGAACTCGCTGATTATCAGGCACTGGACGCAGATATTATTCAATGCATCCAGCGCGCAGAT
GAAGTGCACACCATGACATCATTGTCCGGGTTTGAAGCGTTATTACATGGCAAGCAAGTTCATTGTTACGGCCTGCCCTT
CTATGCCGGTTGGGGTTTAACCGTTGATGAACATCATTGCCCGCGCCGCGAGCGCAGATTAACGATAGCAGACTTGATCT
ATCAGGCGTTGATTGTTTACCCAACATATATTCACCCAACACGGCTACAGCCTATTACGGTTGAGGAAGCTGCGGAATAT
TTAATCCAGACGCCGCGTAAGCCGATGTTTATTACCCGAAAAAAAGCGGGGCGGGTAATACGCTATTGCCGCAAATTAAT
TATGTTCTGCAAGGTCAGATTTGGCTAA

Protein sequence :
MIGIYSPGIWRIPHLEKFLAQPCQKLSLLRPVPQEVDAIAVWGHRPSAAKPVAIAKAAGKPVIRLEDGFVRSLDLGVNGE
PPLSLVVDDCGIYYDASKPSALEKLVQDKAGNTALISQAREAMHTIVTGDLSKYNLAPAFVADESERADIVLVVDQTFND
MSVTYGNAGPHEFAAMLEAAMAENPQAEIWVKVHPDVLEGKKTGYFADLRATQRVRLIAENVSPQSLLRHISRVYVVTSQ
YGFEALLAGKPVTCFGQPWYAGWGLTDDRHPQSALLSARRGSATLEELFAAAYLRYCRYIDPQTGEVSDLFTVLQWLQLQ
RRHLQQRDGYLWAPGLTLWKSAILKPFLQTATNRLSFSRRCTAASACVVWGVKGEQQWRAEAQRKSLPLWRMEDGFLRSS
GLGSDLLPPLSLVLDKRGIYYDATRPCDLEVLLNHSQLTLAQQMRAEKLRQRLVESKLSKYNLGADFSLPAEAKGKKVIL
VPGQVEDDASIKTGTVSIKSNLELLRTVRERNPHAYIIYKPHPDVLVGNRKGNIPAELIAELADYQALDADIIQCIQRAD
EVHTMTSLSGFEALLHGKQVHCYGLPFYAGWGLTVDEHHCPRRERRLTIADLIYQALIVYPTYIHPTRLQPITVEEAAEY
LIQTPRKPMFITRKKAGRVIRYCRKLIMFCKVRFG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 0.0 98
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 0.0 98
kpsC CAE85214.1 KpsC protein Virulence PAI V 536 Protein 2e-176 93
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 3e-127 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
kpsC YP_002399452.1 Capsule polysaccharide export protein VFG0259 Protein 1e-127 50
kpsC YP_002399452.1 Capsule polysaccharide export protein VFG0692 Protein 3e-117 47
kpsC YP_002399452.1 Capsule polysaccharide export protein VFG0704 Protein 1e-104 47