Gene Information

Name : ECED1_3560 (ECED1_3560)
Accession : YP_002399419.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Virulence
Product : bifunctional enterobactin receptor/adhesin protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG4771
EC number : -
Position : 3485005 - 3487095 bp
Length : 2091 bp
Strand : -
Note : IrgA-homologue adhesin (Iha); TonB-dependent; acts as a specific receptor of enterobactin; fur-regulated; urovirulence factor

DNA sequence :
ATGCGAATAACCACTCTGGCTTCTGTCATCATTCCCTGCCTCGGATTCTCAGCCAGCAGCATGGCTGCTGCAGAGGATGT
GATGATTGTCTCGGCATCCGGCTATGAGAAAAAACTGACTAACGCAGCCGCCAGTGTCTCTGTGATCAGCCAGGAGGAAT
TGCAGTCCAGGCAGTACCACGATCTGGCGGAGGCTCTGAGATCTGTCGAGGGTGTGGATGTTGAAAGTGGTACGGGTAAA
ACCGGTGGGCTGGAAATCAGCATCCGTGGAATGCCTGCCAGTTACACGCTGATACTGATTGATGGTGTTCGTCAGGGCGG
GAGCAGTGACGTGACTCCCAACGGTTTTTCTGCCATGAATACCGGGTTCATGCCTCCTCTGGCCGCCATTGAGCGTATTG
AGGTTATCAGGGGGCCGATGTCCACACTGTATGGCTCTGATGCGATGGGCGGTGTGGTGAATATCATTACCAGAAAGAAT
GCAGACAAATGGCTCTCTTCCGTCAATGCAGGGCTGAATCTGCAGGAAAGCAACAAATGGGGTAACAGCAGCCAGTTTAA
TTTCTGGACCAGTGGTCCCCTTGTGGATGATTCTGTCAGTCTGCAGGTCCGGGGCAGCACACAGCAGCGTCAGGGCTCAT
CGGTCACATCACTGAGCGACACAGCAGCCACGCGTATTCCTTATCCCACGGAGTCACAGAATTATAATATTGGTGCGCGT
CTTGACTGGAAAGCCACGGAGCAGGATGTACTCTGGTTTGATATGGATACCACCCGGCAGCGTTATGATAACCGGGACGG
GCAGCTGGGGAGTCTGACCGGGGGATATGACCGTACCCTGCGCTATGAGCGAAACAAAATTTCAGCTGGCTATGATCATT
CTTTCACCTTCGGTACCTGGAAATCGTATCTGAACTGGAACGAGACGGAAAATAAAGGTCGTGAACTTGTACAAAGTGTA
CTGAAGCGCGACAAATGGGAGCTTGCCGGTCAGCCGCGGGAGCTTAAGGAATCTAACTTTATCCTGAATTCATTACTGCT
TACCCCTCTGGGAGAATCTCATCTGGTTACGGTGGGGGGCGAGTATCAGAGTTCGTCCATGAAAGACGGGGTTGTCCTTG
CCAGCACAGGTGAAACTTTCCGGCAGAAAAGCTGGTCGGTATTTGCGGAGGATGAGTGGCATCTTACGGATGCACTTGCG
CTGACTGCGGGCAGCCGCTATGAACATCATGAGCAATTCGGGGGACACTTCAGTCCGCGTGCATATCTGGTCTGGGATGT
GGCAGATGCCTGGACGCTGAAAGGCGGTGTGACCACGGGATATAAAGCCCCCACCATGGGACAGTTACATAAGGGGATCA
GCGGTGTATCCGGGCAGGGACGTACTAATCTACTCGGTAACCCCGAACTGAAGCCGGAAGAGAGTGTAAGTTATGAGGCG
GGGGTATATTACGATAACCTCTCCGGTCTGAATGCCAATATAACAGGCTTTATAACAGACTTCTCCAACAAGATTGTCTC
TTATTCCATTGATGATAACACCAATAGCTATACAAACAGCGGAAAGGCCCGCTTGCATGGTGTGGAATTTGCCGGCACAT
TGCCGCTGTGGTCAGAGGATGTCACTCTGTCGTTGAATTACACCTGGACCCGAAGTGAACAACGTGATGGTGATAACAAA
GGTGCACCGCTGAGCTATACTCCTGAACACATGGTGAATGCGAAACTGAACTGGCAGATCACCGAAGAAGTTGCGTCATG
GCTGGGGGCTCGCTATCGCGATAAAACTCCACGCTTCACCCGGAATTATTCGTCGCTGAGCGCTGTACAGAAGAAAGTGT
ATGATGAGAAAGGAGAATATCTGAAAGCCTGGACGGTGGTGGATGCAGGTCTGTCGTGGAAGGTGACGGATGCCCTGACG
CTGAATGCTGCGGTGAATAACCTGCTCAACAAGGATTACAGTGACGTGAGCCTGTACAGTGCCGGTAAGAGTACGCTTTA
TGCCGGTGATTACTTCCAGACGGGATCATCAACAACGGGCTATGTGATACCTGAGCGAAATTACTGGATGTCACTGAACT
ATCAGTTCTGA

Protein sequence :
MRITTLASVIIPCLGFSASSMAAAEDVMIVSASGYEKKLTNAAASVSVISQEELQSRQYHDLAEALRSVEGVDVESGTGK
TGGLEISIRGMPASYTLILIDGVRQGGSSDVTPNGFSAMNTGFMPPLAAIERIEVIRGPMSTLYGSDAMGGVVNIITRKN
ADKWLSSVNAGLNLQESNKWGNSSQFNFWTSGPLVDDSVSLQVRGSTQQRQGSSVTSLSDTAATRIPYPTESQNYNIGAR
LDWKATEQDVLWFDMDTTRQRYDNRDGQLGSLTGGYDRTLRYERNKISAGYDHSFTFGTWKSYLNWNETENKGRELVQSV
LKRDKWELAGQPRELKESNFILNSLLLTPLGESHLVTVGGEYQSSSMKDGVVLASTGETFRQKSWSVFAEDEWHLTDALA
LTAGSRYEHHEQFGGHFSPRAYLVWDVADAWTLKGGVTTGYKAPTMGQLHKGISGVSGQGRTNLLGNPELKPEESVSYEA
GVYYDNLSGLNANITGFITDFSNKIVSYSIDDNTNSYTNSGKARLHGVEFAGTLPLWSEDVTLSLNYTWTRSEQRDGDNK
GAPLSYTPEHMVNAKLNWQITEEVASWLGARYRDKTPRFTRNYSSLSAVQKKVYDEKGEYLKAWTVVDAGLSWKVTDALT
LNAAVNNLLNKDYSDVSLYSAGKSTLYAGDYFQTGSSTTGYVIPERNYWMSLNYQF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAC39288.1 hypothetical protein Not tested LPA Protein 0.0 97
Z1178 NP_286713.1 bifunctional enterobactin receptor/adhesin protein Virulence TAI Protein 0.0 97
Z1617 NP_287121.1 bifunctional enterobactin receptor/adhesin protein Not tested TAI Protein 0.0 97
c3610 NP_755485.1 bifunctional enterobactin receptor/adhesin protein Not tested PAI I CFT073 Protein 0.0 97
ECUMN_3356 YP_002414032.1 bifunctional enterobactin receptor/adhesin protein Virulence Not named Protein 0.0 97
r4 AAC61730.1 exogenous ferric siderophore receptor R4 Not tested PAI I CFT073 Protein 0.0 97
iha AAF36432.2 adhesin Virulence TAI Protein 0.0 97

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECED1_3560 YP_002399419.1 bifunctional enterobactin receptor/adhesin protein VFG1731 Protein 0.0 97