Gene Information

Name : int (ECED1_3324)
Accession : YP_002399202.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Unknown
Product : Integrase from prophage
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 3263297 - 3264550 bp
Length : 1254 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin

DNA sequence :
ATGCGTATAGGACAAAATCGTTTTTTGGGGGCTATACACATGTTGCTTTCAGACCTTGCTATCCGCCGCGCGAAGCCAAA
AGAGAAAGCCTATACACTCAATGACGGCAACGGGCTTTCGTTACTCATTGAGCCGAACGGTTCGAAGGGCTGGCGATTGC
GATACAGGTTTGCAGGCAAGCCCAAAATGTTGTCGCTGGGTGTCTATCCTGAGGTGTCCCTTTCTGATGCCAGGACGGCA
AGGGATGAAGCCAAAAGGCTTATCGCTGGTGGAGTTAATCCGAGTGAGGTCAGAAAGGCCCAAAAGCGAGAACAGGCGAA
CAAATGCGGTAACACCTTTGAGGTGATCGCCCGTGAGTGGTATGAAAAACGCCTGGACCGATGGTCTCCCTCATATGCAG
AGGAAATGATAGAGACGTTTGAAAAAGACGTTTTTCCGTACATTGGAGGTAGGCCCATCGCAGAGATTAAGCCGATGGAA
TTGCTCGCGGTTCTATCCCGTCTTAATGACCGTGGCGCAACTGAAAAATTGCGTAAGGTTCGCCAGCGATGTGGCGAAGT
GTTTCGGTACGCAATAATTACCGGACGCGCTGAATATAACCCCGCTCCTGATCTGGCAAGCGCATTTGCACCACACAAAA
AAGAGCATTACGCGTATCTGAAAGTTGATGAGCTACCGGAATTTTTCCGCGTTTTTAATACGTACACCGGAAGCCAGATC
GTCAAGCTGGGTATGCGATTGTTGATTCTTACAGGACTCCGTCCGGGTGAATTGCGGCAGGCAGAGTGGCAGGAGATTGA
TTTTGATAATCGTCTGTGGGAAGTGCCGAAAGAACGAATGAAAATGCGCCGTCCTCATTGCGTGCCGCTTTCAGAACAGG
CGATTGCTATTCTGGAACAACTGAAACACATGACGGGGCAGTATCCGTTTATTTTCCCTGGTCGAATACAGCACAGTAAA
CCGATGAGTGAAATGGCGATGAACGTGCTTATTCGTCGTATTGGCTATGCTGGGCGCGTTACTGGTCATGGGTTCCGGCA
TACCATGAGTACAATTTTGCATGAGCAGGGTTATAACTCCGCGTGGATAGAAACGCAGCTGGCGCACGTCGATAAAAACT
CGATCCGTGGCACATACAATCACGCGCAATATCTGGACGGACGGCGGGAGATGCTCCAGTGGTACGCCGACTATATGGAC
TCACTGGAACAGGGCGGAAACGTGGTGCACGGCAAGTTTAGTGTATGTGCATAA

Protein sequence :
MRIGQNRFLGAIHMLLSDLAIRRAKPKEKAYTLNDGNGLSLLIEPNGSKGWRLRYRFAGKPKMLSLGVYPEVSLSDARTA
RDEAKRLIAGGVNPSEVRKAQKREQANKCGNTFEVIAREWYEKRLDRWSPSYAEEMIETFEKDVFPYIGGRPIAEIKPME
LLAVLSRLNDRGATEKLRKVRQRCGEVFRYAIITGRAEYNPAPDLASAFAPHKKEHYAYLKVDELPEFFRVFNTYTGSQI
VKLGMRLLILTGLRPGELRQAEWQEIDFDNRLWEVPKERMKMRRPHCVPLSEQAIAILEQLKHMTGQYPFIFPGRIQHSK
PMSEMAMNVLIRRIGYAGRVTGHGFRHTMSTILHEQGYNSAWIETQLAHVDKNSIRGTYNHAQYLDGRREMLQWYADYMD
SLEQGGNVVHGKFSVCA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 1e-125 64
int CAC39282.1 integrase Not tested LPA Protein 2e-126 63
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-126 63
int AAC31482.1 CP4-like integrase Not tested LEE Protein 1e-125 62
int ACU09430.1 integrase Not tested LEE Protein 1e-125 62
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 1e-125 62
ECs4534 NP_312561.1 integrase Not tested LEE Protein 1e-125 62
int AAD44730.1 Int Not tested SHI-2 Protein 9e-125 62
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 2e-124 62
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 2e-124 62
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 2e-124 62
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 3e-118 57
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-72 43
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 5e-72 42
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 8e-72 42
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 1e-71 42
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 1e-69 42
int AAL51028.1 CP4-like integrase Not tested LEE Protein 6e-72 42
int-phe AAL60261.1 Int-phe Not tested LEE Protein 6e-72 42
int AAL51003.1 CP4-like integrase Not tested LEE Protein 5e-72 42
int AAK16198.1 Int Not tested PAI-I AL862 Protein 4e-72 42
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 4e-71 42
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 4e-72 42
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 3e-71 42
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 4e-72 42
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 7e-72 42
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 8e-72 42
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 6e-72 42
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 8e-72 42
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 4e-73 42
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 4e-73 42
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 7e-72 41
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 7e-72 41
intA AAB00935.1 integrase A Not tested vap locus Protein 1e-62 41
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 3e-68 41
int CAC81896.1 integrase Not tested LEE II Protein 1e-64 41
int AAN62223.1 putative integrase Not tested PAGI-3(SG) Protein 2e-62 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
int YP_002399202.1 Integrase from prophage VFG0783 Protein 6e-126 62
int YP_002399202.1 Integrase from prophage VFG0598 Protein 1e-124 62
int YP_002399202.1 Integrase from prophage VFG1693 Protein 7e-73 43
int YP_002399202.1 Integrase from prophage VFG0626 Protein 3e-72 41
int YP_002399202.1 Integrase from prophage VFG1536 Protein 2e-68 41