Gene Information

Name : irp (ECED1_2251)
Accession : YP_002398190.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Virulence
Product : Thiazolinyl-S-HMWP1 reductase YbtU
Function : -
COG functional category : Q : Secondary metabolites biosynthesis, transport and catabolism
COG ID : COG4693
EC number : -
Position : 2188910 - 2190070 bp
Length : 1161 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 11927258; Product type e : enzyme

DNA sequence :
TTGTGCGCAACACATTACGCGCTGGCTTTGCGCAACCTCAACGCAACCGGAGAACACGTTATGATGCCGTCCGCCTCCCC
AAAACAACGCGTACTGATTGTGGGCGCCAAATTTGGCGAAATGTACCTGAATGCCTTTATGCAGCCCCCGGAGGGGCTGG
AACTGGTCGGCCTGCTGGCGCAGGGAAGCGCCCGTTCAAGAGAGCTGGCTCATGCGTTTGGCATTCCGCTGTATACCTCG
CCGGAACAGATAACCAGGATGCCGGATATCGCCTGTATTGTCGTGCGTTCGACCGTCGCCGGAGGAACCGGTACGCAGCT
TGCCAGACACTTTCTGACGCGCGGCGTACACGTCATTCAGGAGCATCCCCTCCACCCGGATGACATCAGTTCCTTACAAA
CGCTGGCGCAGGAACAGGGCTGCTGCTATTGGGTAAACACGTTTTATCCGCATACGCGCGCGGGACGCACATGGCTTCGC
GATGCTCAGCAGCTGCGTCGCTGCCTGGCTAAGACGCCGCCGGTAGTCCACGCCACCACCAGCCGACAGTTGCTCAACTC
CACTCTGGATTTGTTGTTGCTGGCTCTGGGCGTTGATGCCGCCGCCGTGGAGTGCGACGTGGTTGGCAGCTTTAGCGATT
TTCACTGTCTGAGACTCTTCTGGCCGGAGGGAGAAGCCTGCCTGCTGCTTCAGCGCTATCTCGATCCTGACGATCCAGAT
ATGCATAGCCTTATCATGCACCGCCTGCTGCTGGGCTGGCCGGAAGGTCATCTTTCGCTGGAGGCGAGTTACGGCCCCGT
CATCTGGTCATCCAGCCTGTTTGTCGCAGACCATCAGGAGAACGCCCACAGCCTCTACCGCAGACCGGAGATCCTGCGCG
ATCTGCTGGGTCTGACGCGCAGCGCGGCGCCCCTGAGCTGGCGCGACTGCTGCGAAACCGTCGGGCCGGAGGGCGTCAGC
TGGTTGCTACACCAGTTGCGCAGCCATCTGGCGGGCGAACATCCACCAGCGGCCTGCCAAAGCGTACATCAGATCGCGTT
ATCACGTTTATGGCAGCAGATTTTACGTAAGACCGGCAATGCGGAGATCAGACGCCTGACACCGCCGCACCACGACCGGT
TAGCCGGTTTCTACAACGATGATGATAAGGAGGCGCTGTGA

Protein sequence :
MCATHYALALRNLNATGEHVMMPSASPKQRVLIVGAKFGEMYLNAFMQPPEGLELVGLLAQGSARSRELAHAFGIPLYTS
PEQITRMPDIACIVVRSTVAGGTGTQLARHFLTRGVHVIQEHPLHPDDISSLQTLAQEQGCCYWVNTFYPHTRAGRTWLR
DAQQLRRCLAKTPPVVHATTSRQLLNSTLDLLLLALGVDAAAVECDVVGSFSDFHCLRLFWPEGEACLLLQRYLDPDDPD
MHSLIMHRLLLGWPEGHLSLEASYGPVIWSSSLFVADHQENAHSLYRRPEILRDLLGLTRSAAPLSWRDCCETVGPEGVS
WLLHQLRSHLAGEHPPAACQSVHQIALSRLWQQILRKTGNAEIRRLTPPHHDRLAGFYNDDDKEAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtU YP_853077.1 yersiniabactin biosynthetic protein Virulence PAI IV APEC-O1 Protein 7e-161 99
ybtU CAA21392.1 - Virulence HPI Protein 5e-161 99
irp3 YP_002346900.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 1e-161 99
ybtU NP_669708.2 thiazolinyl-S-HMWP1 reductase Virulence HPI Protein 1e-161 99
ybtU NP_993005.2 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 1e-161 99
ybtU YP_070122.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 1e-161 99
irp3 YP_001006817.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 5e-162 98
irp3 CAA73128.1 Irp3 protein Virulence HPI Protein 2e-161 98
nrpU YP_002152319.1 siderophore biosynthetic protein Virulence Not named Protein 4e-63 43