Gene Information

Name : irp (ECED1_2247)
Accession : YP_002398186.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Virulence
Product : yersiniabactin-iron ABC transporter permease ATP-binding protein YbtP
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1132
EC number : -
Position : 2170168 - 2171970 bp
Length : 1803 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter

DNA sequence :
ATGTCATCTCAATCATCCAATACTGAATCGCTGTCCCGATTTCCTCTCTGGCAGGTGATTACACCGGTTCGCAGGAAGGT
TATTTTAGCTATGGCGCTGGCGGGGCTGGCGGCATTAACCAGCCTGGGGGCGCTCCTTTTTCTAGCGTGGAGCCTGCGTG
ACATTCGCGCGACGCCTGACGCTATTCCGGCCTGGCCGCTGGGCGGCGTGATCGGCTGCGTGGTCTTAACTTTTGTTCTG
CGCTTACAGGCGTTCAACACCTCTCATTACGCGGCTTTTCATCTGGAGAACATTCTGCGCAGCAGGTTAGCCCGTAAAGC
ATTGCAGCTTCCGCCTGGCGTGTTACAGCAAATGGGCAGCGGGTCAGTGGCGAAAGTGATGCTGGATGACGTGAAGTCGT
TACATATTTTTGTGGCCGACAGCACGCCGCTCTATGCCCGCGCGATCATCATGCCGCTGGCGACAATCGTTATCTTGTTC
TGGCTGGACTGGCGGCTGGCAATCGCGACGCTGGGGGTACTGGCGTTTGGATCGGTTGTTCTCGTGCTCGCCCGCCAGCG
TTCGGAAGATATGGCTCAGCGTTATCATAAGGCGCGCGAGCAGGTTAGCGCGGCGGTGATTGAGTTCGTGCAGGCCATGC
CCGTGGTGAGAACGTTTGATAGCGGCAGCACCAGTTTTTTGCGCTATCAACGAGCCCTTGAAGAGTGGGTCGATGTGCTC
AAAACCTGGTATCGCAAAGCCGGTTTTTCAGCGCGTTTTTCCTTCTCGATTCTGAATCCTCTCCCGACCCTGTTTGTCCT
GATCTGGTCGGGATACGGCCTGCTGCACTATGGCAGTTTCGATTTTATCGCGTGGGTGGCCGTTTTACTGCTGGGCAGCG
GAATGGCCGAAGCCGTAATGCCAATGATGATGCTCAATAACCTGGTCGCGCAAACGCGTTTAAGCATTCAGCGTATTTAT
CAGGTTCTCGCGATGCCGGAGTTATCGCTGCCGCAGTCTGACCAGCAGCCGCAAGAGGCGAGCATTACCTTTGAGCAGGT
GAGCTTTCATTATCCGCAAGCGCGTACTGGCGCCGCGTTGCAGGAGGTGAGCTTTCATGTGCCTGCCGGGCAAATTGTGG
CGCTGGTCGGGCCAAGCGGCGCCGGAAAAAGCACCGTGGCGCGCTTGCTGCTGCGTTACGCCGACCCGGACAAAGGCCAT
ATCCGTATTGGAGGCGTGGATCTGCGTGATATGCAGACGGACACCCTGATGAAGCAACTCTCGTTTGTGTCTCAGGACAA
CTTCCTTTTTGCCGACACGATAGCCAATAACATTCGTCTGGGCGCGCCGGATACGCCGCTGGAGGCGGTAATAGCGGCGG
CCAGAGTGGCGCAGGCCCATGATTTTATTAGCGCTCTGCCAGAAGGTTACAACACACGAGTCGGGGAACGTGGGGTATTT
CTCTCCGGCGGCCAGCGGCAGCGCATTACTATCGCCCGGGCGCTTTTGCAGGATCGCCCCATCCTGGTGCTCGATGAGGC
GACGGCGTTTGCTGACCCGGAAAACGAAGCGGCGCTTATCAAGGCGCTCGCGGCGGCCATGCGTGGCCGGACGGTCATCA
TGGTCGCGCATCGTCTCTCAATGGTGACTCAGGCCGATGTGATATTGCTGTTTTCCGACGGACAGCTCAGGGAAATGGGG
AACCATACGCAACTGTTGGCGCAGGGCGGCCTGTATCAACGGCTCTGGCAACACTATCAGCAGGCGCAGCATTGGGTGCC
GGGTGGAACACAGGAAGAGGTGGTGGAAAATGAAAGACAATAA

Protein sequence :
MSSQSSNTESLSRFPLWQVITPVRRKVILAMALAGLAALTSLGALLFLAWSLRDIRATPDAIPAWPLGGVIGCVVLTFVL
RLQAFNTSHYAAFHLENILRSRLARKALQLPPGVLQQMGSGSVAKVMLDDVKSLHIFVADSTPLYARAIIMPLATIVILF
WLDWRLAIATLGVLAFGSVVLVLARQRSEDMAQRYHKAREQVSAAVIEFVQAMPVVRTFDSGSTSFLRYQRALEEWVDVL
KTWYRKAGFSARFSFSILNPLPTLFVLIWSGYGLLHYGSFDFIAWVAVLLLGSGMAEAVMPMMMLNNLVAQTRLSIQRIY
QVLAMPELSLPQSDQQPQEASITFEQVSFHYPQARTGAALQEVSFHVPAGQIVALVGPSGAGKSTVARLLLRYADPDKGH
IRIGGVDLRDMQTDTLMKQLSFVSQDNFLFADTIANNIRLGAPDTPLEAVIAAARVAQAHDFISALPEGYNTRVGERGVF
LSGGQRQRITIARALLQDRPILVLDEATAFADPENEAALIKALAAAMRGRTVIMVAHRLSMVTQADVILLFSDGQLREMG
NHTQLLAQGGLYQRLWQHYQQAQHWVPGGTQEEVVENERQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtP YP_853073.1 inner membrane ABC-transporter Not tested PAI IV APEC-O1 Protein 0.0 99
irp6 YP_002346904.1 lipoprotein inner membrane ABC transporter Not tested HPI Protein 0.0 99
ybtP CAA21388.1 - Virulence HPI Protein 0.0 99
ybtP NP_669704.1 permease and ATP-binding protein of yersiniabactin-iron ABC transporter Virulence HPI Protein 0.0 99
ybtP NP_993009.1 permease and ATP-binding protein of yersiniabactin-iron ABC transporter Virulence HPI Protein 0.0 99
irp6 YP_001006813.1 lipoprotein inner membrane ABC-transporter Not tested HPI Protein 0.0 99
ybtP YP_070126.1 lipoprotein inner membrane ABC-transporter Virulence HPI Protein 0.0 99
irp6 CAB46573.1 lipoprotein inner membrane ABC-transporter, Irp6 Virulence HPI Protein 0.0 98

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
irp YP_002398186.1 yersiniabactin-iron ABC transporter permease ATP-binding protein YbtP BAC0432 Protein 0.0 99