Gene Information

Name : irp (ECED1_2246)
Accession : YP_002398185.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Virulence
Product : yersiniabactin-iron ABC transporter permease ATP-binding protein YbtQ
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1132
EC number : -
Position : 2168379 - 2170208 bp
Length : 1830 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 10231486, 11320115; Product type t : transporter

DNA sequence :
GTGGAACACAGGAAGAGGTGGTGGAAAATGAAAGACAATAATCCTGCGGATAACCTGGCCTGGCGCGTCAACTGGCGCCA
GCTTATCTCCAGCGTTGGCAGTCAGGCCAGGATGCTGCGACGCAGTATGCTGGCGCTGTTGCTGGCGGCATTCATGCAGG
GGATCGCCTTTGCCTGTCTTTATCCGATCATTGATGCGCTGTTACGGGGAGACGCGCCGCAACTTCTTAACTGGGCTATG
GCCTTCAGCGTCGCCGCAATTGTGACGCTGGTGCTACGCTGGTATGGCCTGGGCTTTGAATACCGTGGTCATCTGGCGCA
GGCCACCCATGAGTTGCGCCTGCGACTTGGCGAGCAGTTACGCCGCGTGCCGCTGGAGAAGCTCCAGCGCGGCAGGGCGG
GTGAAATGAACGCCTTGCTGCTGGGCAGCGTGGATGAAAACCTCAATTATGTTATTGCGATAGCCAATATTTTGCTGCTC
ACCATTGTCACGCCGCTGACGGCGTCGCTGGCGACATTGTGGATAGACTGGCGGCTGGGGCTGGTGATGTTGCTGATCTT
CCCTCTGCTGGTGCCGTTTTATTACTGGCGCCGCCCGGCGATGCGGCGACAAATGCAGACGCTGGGGGAAGCGCACCAGC
GTCTGAGCGGCGATATCGTTGAATTTGCTCAGGGGATGATGGTATTGCGCACCTGCGGCAGCGATGCCGATAAAAGCCGG
GCGCTGCTGGCGCATTTCAATGCGCTGGAAAACTTACAGACCCGCACTCACCGTCAGGGCGCTGGCGCGACGATGCTGAT
CGCCAGCGTCGTGGAGTTGGGCCTACAGGTGGTGGTGTTATCCGGGATCGTCTGGGTAGTGACGGGCACTCTGAACCTCG
CCTTTTTGATTGCCGCCGTCGCGATGATTATGCGCTTCGCAGAACCGATGGCGATGTTTATCAGCTACACCTCGGTTGTG
GAACTGATCGCCAGCGCCCTGCAACGGATTGAGCGGTTTATGGCGATAGCACCGCTTCCCGTCGCAGAGCAAAGCGAGAT
GCCGGAACGTTACGATATCCGCTTTGACAACGTCAGCTATCGCTACGAAGAAGGCGACGGCCACGCGCTTAATCATGTTT
CTTTGACGTTCCCGGCAGCCAGTATGAGCGCGCTGGTGGGTGCCTCCGGCGCAGGCAAAACTACGGTCACCAAACTGTTA
ATGCGCTATGCCGATCCGCAGCAAGGGCAGATTTCTATTGGCGGCGTCGATATTCGCCGCCTGACGCCGGAACAGCTCAA
TAGCCTGATTTCTGTTGTTTTCCAGGATGTCTGGCTGTTTGATGACACGCTGCTGGCGAATATCCGTATCGCGCGCCCAC
AGGCGACGCGGCAGGAGGTAGAAGAGGCCGCCCGCGCGGCGCAGTGCCTTGAGTTTATTTCCCGTCTTCCGCAAGGCTGG
CTGACGCCAATGGGAGAGATGGGCGGCCAGCTATCGGGCGGCGAGCGCCAGCGGATTTCCATTGCCAGAGCGTTATTGAA
AAACGCGCCGGTCGTCATTCTCGATGAACCGACTGCCGCGCTGGATATTGAAAGCGAGCTGGCGGTGCAAAAAGCGATCG
ATAACCTGGTTCACAACCGGACGGTGATTATCATCGCTCACCGTTTATCCACCATCGCCGGGGCCGGAAACATTCTGGTG
ATGGAAGAGGGACAGGTGGTTGAGCAGGGTACTCATGCACAATTGCTCTCACATCATGGACGTTATCAGGCGCTGTGGCA
GGCGCAAATGGCCGCGCGCGTGTGGCGCGACGACGGGGTTTCCGCGTCTGGAGAGTGGGTGCATGAGTGA

Protein sequence :
MEHRKRWWKMKDNNPADNLAWRVNWRQLISSVGSQARMLRRSMLALLLAAFMQGIAFACLYPIIDALLRGDAPQLLNWAM
AFSVAAIVTLVLRWYGLGFEYRGHLAQATHELRLRLGEQLRRVPLEKLQRGRAGEMNALLLGSVDENLNYVIAIANILLL
TIVTPLTASLATLWIDWRLGLVMLLIFPLLVPFYYWRRPAMRRQMQTLGEAHQRLSGDIVEFAQGMMVLRTCGSDADKSR
ALLAHFNALENLQTRTHRQGAGATMLIASVVELGLQVVVLSGIVWVVTGTLNLAFLIAAVAMIMRFAEPMAMFISYTSVV
ELIASALQRIERFMAIAPLPVAEQSEMPERYDIRFDNVSYRYEEGDGHALNHVSLTFPAASMSALVGASGAGKTTVTKLL
MRYADPQQGQISIGGVDIRRLTPEQLNSLISVVFQDVWLFDDTLLANIRIARPQATRQEVEEAARAAQCLEFISRLPQGW
LTPMGEMGGQLSGGERQRISIARALLKNAPVVILDEPTAALDIESELAVQKAIDNLVHNRTVIIIAHRLSTIAGAGNILV
MEEGQVVEQGTHAQLLSHHGRYQALWQAQMAARVWRDDGVSASGEWVHE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp7 YP_002346905.1 ABC transporter permease Not tested HPI Protein 0.0 99
ybtQ NP_669703.1 permease and ATP-binding protein of yersiniabactin-iron ABC transporter Virulence HPI Protein 0.0 99
ybtQ NP_993010.1 ABC transporter permease Virulence HPI Protein 0.0 99
ybtQ YP_070127.1 ABC transporter permease Virulence HPI Protein 0.0 99
ybtQ CAA21387.1 - Virulence HPI Protein 0.0 99
APECO1_1055 YP_853072.1 ABC transporter Not tested PAI IV APEC-O1 Protein 0.0 99
irp7 CAB46572.1 inner membrane ABC-transporter, Irp7 Virulence HPI Protein 0.0 99
irp7 YP_001006812.1 inner membrane ABC-transporter YbtQ Not tested HPI Protein 0.0 99

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
irp YP_002398185.1 yersiniabactin-iron ABC transporter permease ATP-binding protein YbtQ BAC0433 Protein 0.0 99