Gene Information

Name : irp (ECED1_2244)
Accession : YP_002398183.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Virulence
Product : salicylate synthase Irp9
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0147
EC number : -
Position : 2165774 - 2167078 bp
Length : 1305 bp
Strand : -
Note : catalyzes the conversion of chorismate to salicylate in the biosynthesis of the siderophore yersiniabactin

DNA sequence :
ATGAAAATCAGTGAATTTTTACACCTGGCGTTACCAGAGGAACAATGGCTGCCGACGATTTCTGGCGTTTTACGCCAGTT
CGCAGAAGAAGAGTGTTATGTCTATGAGCGTCAACCCTGTTGGTATTTAGGCAAAGGGTGCCTGGCACGGTTGCACATTA
ATGCCGACGGAACGCAGGCGACATTTATTGATGATGCCGGGGAGCAACAATGGGCGGTGGATTCCATTACCGACTGCGCG
CGTCGTTTTATGGCACATCCTCAGGTGAAAGGACGTCGGGTTTATGGACAGGTTGGGTTCAACTTTGCGGCGCATGCGCG
GGGGATTGCCTTTAACGCCGGGGAGTGGCCGCTGCTGACGTTAACCGTTCCCCGTGAAGAACTTATTTTTGAAAAGGGAA
ATGTCACCGTTTATGCGGACTCCGCCGACGGGGGCCGACGTTTGTGTGAGTGGGTAAAAGAGGCCAGTACAACGACGCAG
AACGCACCACTGGCGGTGGATACCGCCCTCAATGGCGAGGCGTATAAACAACAGGTTGCACGCGCCGTTGCGGAGATCCG
CCGTGGCGAGTATGTCAAAGTGATTGTCTCGCGCGCTATTCCCCTGCCATCGCGGATTGATATGCCCGCCACGCTGTTAT
ACGGGCGGCAGGCAAATACACCTGTGCGCTCGTTTATGTTCCGTCAGGAAGGACGCGAAGCGCTGGGCTTTAGCCCGGAA
CTGGTGATGTCAGTGACGGGCAATAAAGTGGTCACTGAACCGCTTGCGGGCACCCGCGATCGCATGGGAAACCCGGAGCA
TAATAAGGCGAAAGAGGCAGAACTGCTGCACGACAGTAAAGAGGTGCTTGAGCATATCCTTTCTGTCAAAGAAGCGATTG
CTGAACTGGAGGCCGTTTGCCTGCCGGGCAGCGTGGTGGTTGAAGATTTAATGTCGGTTCGCCAGCGCGGCAGCGTTCAG
CATCTGGGGTCCGGCGTGAGCGGTCAGCTTGCGGAAAACAAGGATGCCTGGGATGCGTTTACCGTGCTGTTTCCGTCGAT
TACCGCCTCAGGTATCCCTAAAAACGCTGCCCTGAACGCGATTATGCAAATTGAGAAGACGCCGCGAGAGCTCTATTCCG
GCGCAATTCTGCTGCTGGACGATATGCGCTTCGATGCGGCGCTAGTTCTGCGTTCCGTATTTCAGGACAGCCAGCGCTGC
TGGATACAAGCGGGGGCGGGAATCATCGCGCAATCTACACCGGAACGCGAACTGACGGAAACCCGGGAGAAATTAGCGAG
CATTGCGCCCTATTTAATGGTGTAG

Protein sequence :
MKISEFLHLALPEEQWLPTISGVLRQFAEEECYVYERQPCWYLGKGCLARLHINADGTQATFIDDAGEQQWAVDSITDCA
RRFMAHPQVKGRRVYGQVGFNFAAHARGIAFNAGEWPLLTLTVPREELIFEKGNVTVYADSADGGRRLCEWVKEASTTTQ
NAPLAVDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQANTPVRSFMFRQEGREALGFSPE
LVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELLHDSKEVLEHILSVKEAIAELEAVCLPGSVVVEDLMSVRQRGSVQ
HLGSGVSGQLAENKDAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDMRFDAALVLRSVFQDSQRC
WIQAGAGIIAQSTPERELTETREKLASIAPYLMV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtS YP_002346907.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
ybtS NP_669701.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
ybtS YP_070129.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
ybtS CAA21385.1 - Virulence HPI Protein 0.0 99
irp9 YP_001006810.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
irp9 CAB46570.1 salicylate synthetase, Irp9 Virulence HPI Protein 0.0 99
ybtS NP_993012.1 salicylate synthase Irp9 Not tested HPI Protein 0.0 99
APECO1_1052 YP_853070.1 salicylate synthase Irp9 Not tested PAI IV APEC-O1 Protein 0.0 99
unnamed AAD17661.1 unknown Not tested HPI Protein 0.0 92