Gene Information

Name : int (ECED1_2243)
Accession : YP_002398182.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 2164318 - 2165580 bp
Length : 1263 bp
Strand : +
Note : Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin

DNA sequence :
ATGTCCCTTACCGACGCGAAAATCCGCACTCTCAAACCTTCTGATAAACCCTTTAAAGTCTCCGATTCCCACGGTCTGTA
TCTGCTGGTCAAGCCGGGTGGCTCACGTCACTGGTATCTCAAGTACCGTATTAACGGTAAAGAATCGCGCATTGCGCTGG
GTGCCTATCCTGCCGTCTCCCTCTCTGATGCGCGACAGCAGCGTGAAGGTGTCCGTAAAATGCTGGCGCTGAATATCAAC
CCGGTACAGCAGCGGGCTGCTGAACGTGGCTCACGAACACCGGATAAAGTTTTTAAAAACGTGGCGCTGGCGTGGCATAA
AAGTAACCGGAAATGGTCGCAGAACACCGCTGACCGTCTGCTTGCCAGCCTGAACAATCACATCTTTCCGGTCATTGGCA
ACCTGCCTGTATCAGAACTTAAACCCCGTCATTTCATTGACCTGCTGAAAAGGATCGAGGAAAAAGGTCTGCTGGAAGTT
GCGTCCCGCACGCGGCAGCACCTGAGTAACATAATGCGCCATGCGGTTCATCAGGGGTTAATCGATACGAACCCGGCAGC
AAATCTTGGCGGCGTGACCACACCTCCTGTCAGACGGCACTATCCTGCCCTGCCACTGGAGCGGCTGCCTGAACTGCTTG
AACGTATTGGGGCATATCATCAGGGTCGTGAACTGACGCGGTTGGCCGTCCTGCTGATGCTGCATGTGTTCATTCGCTCC
AGTGAACTGCGTTTCGCCCGCTGGTCAGAGATTGATTTCACAAACCGAGTCTGGACGATACCCGCGACGCGAGAACCCAT
TATTGGAGTGCGTTATTCCGGCCGCGGGGCCAAAATGCGAATGTCGCATATCGTCCCCCTCTCAGAACAGTCCATCGCCA
TTCTGAAACAGATTAAGGATATCACCGGTAATAATGAACTGATCTTCCCCGGCGACCATAACCCGTATAAGCCAATGTGT
GAAAACACGGTCAATAAGGCACTGCGGGTGATGGGCTACGACACGAAAAAGGATATCTGCGGTCACGGCTTCCGGGCAAT
GGCATGCAGTGCGCTGATGGAATCGGGTTTATGGGCAAAGGACGCAGTAGAACGCCAGATGAGTCATCAGGAGCGCAATA
CCGTGCGCATGGCTTATATTCATAAGGCAGAGCACCTAGAAGCCCGCAAAGCGATGATGCAGTGGTGGTCGGATTATCTG
GAAGCATGCCGAGAATCTTATGCACCGCCTTATACAATTGGTAAAAATAAGTTTATCCCATAG

Protein sequence :
MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRINGKESRIALGAYPAVSLSDARQQREGVRKMLALNIN
PVQQRAAERGSRTPDKVFKNVALAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKRIEEKGLLEV
ASRTRQHLSNIMRHAVHQGLIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGAYHQGRELTRLAVLLMLHVFIRS
SELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRGAKMRMSHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMC
ENTVNKALRVMGYDTKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAMMQWWSDYL
EACRESYAPPYTIGKNKFIP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int CAA08754.1 integrase Not tested HPI Protein 0.0 99
int CAB59974.1 integrase Not tested HPI Protein 0.0 99
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 4e-155 98
int CAA21384.1 - Not tested HPI Protein 0.0 98
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 2e-139 98
int YP_002346908.1 integrase Not tested HPI Protein 0.0 98
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 0.0 98
int2 NP_993013.1 integrase Not tested HPI Protein 0.0 98
unnamed AAD17660.1 unknown Not tested HPI Protein 0.0 96
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 7e-121 59
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 7e-121 59
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 8e-120 57
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 8e-120 57
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 6e-110 56
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 7e-110 56
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 5e-110 56
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 5e-110 56
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 5e-110 56
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 4e-110 56
int AAK00456.1 Int Not tested SHI-1 Protein 1e-101 56
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 2e-111 56
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 3e-111 56
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 1e-109 56
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 2e-111 56
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 3e-111 56
int AAL51028.1 CP4-like integrase Not tested LEE Protein 2e-111 56
int-phe AAL60261.1 Int-phe Not tested LEE Protein 2e-111 56
int AAK16198.1 Int Not tested PAI-I AL862 Protein 8e-112 56
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 8e-112 56
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 5e-111 56
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 1e-110 56
int AAL51003.1 CP4-like integrase Not tested LEE Protein 3e-111 56
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 1e-110 56
int CAC81896.1 integrase Not tested LEE II Protein 6e-103 56
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 6e-106 55
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 5e-96 50
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 2e-99 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
int YP_002398182.1 integrase VFG0626 Protein 2e-110 56
int YP_002398182.1 integrase VFG1693 Protein 5e-111 56
int YP_002398182.1 integrase VFG1536 Protein 3e-106 55