Gene Information

Name : umuC (ECED1_1326)
Accession : YP_002397339.1
Strain : Escherichia coli ED1a
Genome accession: NC_011745
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : -
Position : 1311024 - 1312286 bp
Length : 1263 bp
Strand : +
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTTGCCCTCTGTGATGTAAACGCGTTTTATGCCAGCTGTGAGACGGTGTTTCGCCCTGATTTATGGGGTAAACCGGT
GGTTGTGCTATCGAATAACGACGGTTGCGTTATCGCCCGAAACGCAAAGGCGCTGGGCGTTAAAATGGGCGATCCCTGGT
TCAAACAAAAAGATCTGTTTCGTCGCTGTGGCGTGGTTTGCTTTAGCAGCAATTATGAGCTTTACGCAGACATGAGTAAT
CGGGTGATGTCGACGCTGGAAGAACTATCGCCCCGCGTCGAGATTTACAGTATTGATGAGGCATTCTGCGATCTGACAGG
TGTGCATAATTGTCGCGATCTGACTGATTTTGGCAGAGAAATTTGCGCAACGGTGCTACAACGTACCCATCTTACTGTTG
GTGTGGGGATCGCCCAGACCAAAACGCTGGCTAAGCTTGCCAATCATGCGGCAAAAAAATGGCAGCGGCAGACGGGCGGG
GTGGTGGATTTATCAAATCTGGAACGCCAGCGTAAATTAATGTCTGCTCTCCCCGTGGATGAAGTCTGGGGGATTGGACG
GCGGATCAGCAAAAAACTGGACGCGATGGGGATCAAAACCGTTCTCGATTTGGCGGATTCAGATATCCGGTTTATCCGTA
AACATTTTAATGTCGTGCTCGAAAGAACGGTGCGTGAACTGCGCGGTGAACCCTGTTTGCAACTGGAAGAGTTTGCACCG
ACGAAGCAGGAAATTATCTGTTCCCGCTCGTTTGGTGAACGCATCACGGATTATCCGTCGATGCGGCAGGCCATTTGTAG
TTACGCTGCCCGGGCGGCGGAAAAACTTCGCAGCGAGCATCAATATTGTCGGTTTATCTCCACGTTTATTAAGACGTCAC
CATTTGCGTTCAATGAACCTTATTACGGCAATAGCGCATCGGTAAAACTGCTGACGCCCACTCAGGACAGCAGGGATATC
ATTAACGCCGCTACGCGATCTCTGGATGCCATCTGGCAAGCGGGCCATCGCTACCAAAAAGCGGGCGTGATGCTGGGGGA
TTTCTTCAGTCAGGGAGTCGCGCAGCTCAATTTATTCGATGACAACGCACCGCGCCCCGGGAGTGAGCAATTGATGGCGG
TAATGGATACGCTGAATGCTAAAGAGGGCAGAGGAACACTCTATTTTGCCGGGCAGGGGATCCAGCAACAATGGCAGATG
AAGCGTGCCATGCTTTCACCATGTTATACAACGCGAAGTTCTGATTTACTGCGGGTCAAATAA

Protein sequence :
MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAKALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADMSN
RVMSTLEELSPRVEIYSIDEAFCDLTGVHNCRDLTDFGREICATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQTGG
VVDLSNLERQRKLMSALPVDEVWGIGRRISKKLDAMGIKTVLDLADSDIRFIRKHFNVVLERTVRELRGEPCLQLEEFAP
TKQEIICSRSFGERITDYPSMRQAICSYAARAAEKLRSEHQYCRFISTFIKTSPFAFNEPYYGNSASVKLLTPTQDSRDI
INAATRSLDAIWQAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMAVMDTLNAKEGRGTLYFAGQGIQQQWQM
KRAMLSPCYTTRSSDLLRVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 5e-124 63
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 5e-124 63
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 1e-88 50
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 2e-74 49