Gene Information

Name : ECS88_4719 (ECS88_4719)
Accession : YP_002394206.1
Strain : Escherichia coli S88
Genome accession: NC_011742
Putative virulence/resistance : Virulence
Product : SHI-2 pathogenicity island protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4682287 - 4683360 bp
Length : 1074 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 10411725; Product type pe : enzyme

DNA sequence :
ATGGTCCATCCTTTTTTACAGGTTCAGAATATGACTGGCAAATTACGCTTTGAAGTGAACGATAACCAGGGCTGTTTCAT
ATTTCCGGAAACCTGGTTTGGCTCGTTGCTGGATGAGTTTGAAGAACTGATTGATGCATACGATGCGGATGAAATCAGCG
AAACAAGTTACATCAACAAACTCAGGCGCCTTGCCCGACAGGAGAATGACTTTATTGATGTACACGCTCACTTGGCATAC
GTATTTCTGGAGCAGAATGCCCCGCGTAAGGCGCTGAATGCTGCCCTTAAAGGGCTGGCAGTTGGCAATCGTCTTATCCC
TGAAGGTTTCAGTGGCAGAATCATCTGGATACATCCTGACAACCGACCTTTTCTTCGTGCCCTCTATGCGGCAATCCTGG
CAAATGCACATTTACGGCGTCATCAGGATGCCATCATGCTCATTGAAAAAATACTGGATTACAATCCCGAAGATAATCAT
GGTGCACGCTGGCTACTGGGACCGGAACTGTTACGCACTGGCGCTCATGAACAGGCACGCCATATACTGCAGGAACATGC
AGATGAATTTTCACCTTACTGGTATGAACTCGGCCTTCTGCATTTTCTTAATGGGGAACTGGTAAAAGCTGCAACTGCAT
TTCGTCGCGGCTTTGCGGCAAATACTTACATCGCAGAAATACTGTGCGGAAATCTGCATCCATTTCCACTTGCTGTATGG
CATAACTTTTCAGGCGGTCCGGATACTGCCGAAGATTATTATGCCACATACCACCCGTTATGGGGGCAATATCCGGAAGC
ATTGCTGTTTGTAAACTGGCTCTATAATCATTCCTCTGTGCTGCATGAACGGGCAGAAATCATTAAATGCGCCGAAATGC
TGATGCAGGAAGATGATTTCGAAATATGCGAAAGTATTTTAAGACAGCAGGAGAAGTTGCGTGAAAGAATTGATGAGACG
CTTTCTGAGAAAATTGTACAGAAATGCAGAAATATGAATGGTGAATATGTCTGGCCCTGGATATTGCCGTTTTCAGCGGC
AGGCATGAAACATACTGGCATACAGTATCAGTAG

Protein sequence :
MVHPFLQVQNMTGKLRFEVNDNQGCFIFPETWFGSLLDEFEELIDAYDADEISETSYINKLRRLARQENDFIDVHAHLAY
VFLEQNAPRKALNAALKGLAVGNRLIPEGFSGRIIWIHPDNRPFLRALYAAILANAHLRRHQDAIMLIEKILDYNPEDNH
GARWLLGPELLRTGAHEQARHILQEHADEFSPYWYELGLLHFLNGELVKAATAFRRGFAANTYIAEILCGNLHPFPLAVW
HNFSGGPDTAEDYYATYHPLWGQYPEALLFVNWLYNHSSVLHERAEIIKCAEMLMQEDDFEICESILRQQEKLRERIDET
LSEKIVQKCRNMNGEYVWPWILPFSAAGMKHTGIQYQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3557 NP_755432.1 ShiA-like protein Not tested PAI I CFT073 Protein 3e-161 99
ECUMN_3323 YP_002414005.1 SHI-2 pathogenicity island protein Virulence Not named Protein 4e-167 99
shiA AFX83956.1 ShiA family protein Not tested SE-PAI Protein 9e-156 90
aec34 AAW51717.1 Aec34 Not tested AGI-3 Protein 6e-145 86
shiA NP_839237.1 hypothetical protein Virulence SHI-2 Protein 2e-141 84
shiA NP_709438.1 hypothetical protein Virulence SHI-2 Protein 2e-141 84
shiA AAD44731.1 ShiA Virulence SHI-2 Protein 1e-141 84

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECS88_4719 YP_002394206.1 SHI-2 pathogenicity island protein VFG1694 Protein 1e-161 99
ECS88_4719 YP_002394206.1 SHI-2 pathogenicity island protein VFG0599 Protein 8e-142 84