Gene Information

Name : rph (ECS88_4057)
Accession : YP_002393628.1
Strain : Escherichia coli S88
Genome accession: NC_011742
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 4021885 - 4022625 bp
Length : 741 bp
Strand : -
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
TTGTTTCAAGCCGGAGATTTCAATATGCGTCCAGCAGGCCGTAGCAATAATCAGGTGCGTCCCGTTACCCTGACTCGTAA
CTATACAAAACATGCAGAAGGCTCGGTGCTGGTCGAATTTGGCGATACCAAAGTGTTGTGTACCGCCTCTATTGAAGAAG
GCGTGCCGCGCTTCCTGAAAGGTCAGGGCCAGGGCTGGATCACCGCAGAGTACGGTATGCTGCCGCGTTCTACCCATACC
CGTAACGCGCGTGAAGCGGCGAAAGGTAAGCAGGGTGGACGCACAATGGAAATCCAGCGTCTGATCGCCCGTGCTCTTCG
CGCGGCAGTAGATTTGAAAGCACTGGGTGAGTTCACCATTACGCTGGACTGCGACGTGCTTCAGGCTGATGGTGGCACGC
GTACCGCTTCGATTACGGGTGCCTGCGTGGCGCTGGCAGATGCGCTACAGAAGCTGGTGGAAAACGGCAAGCTGAAAACT
AATCCAATGAAAGGGATGGTAGCCGCGGTCTCTGTCGGGATTGTGAACGGCGAAGCGGTTTGCGATCTGGAATATGTTGA
AGACTCTGCCGCAGAGACCGACATGAACGTAGTGATGACCGAAGACGGGCGTATCATTGAAGTGCAGGGGACGGCAGAAG
GCGAACCGTTCACCCACGAAGAGTTACTCACCTTGTTGGCGCTGGCCCGAGGGGGAATCGAATCCATTGTAGCGACGCAG
AAGGCGGCGCTGGCAAACTGA

Protein sequence :
MFQAGDFNMRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIEEGVPRFLKGQGQGWITAEYGMLPRSTHT
RNAREAAKGKQGGRTMEIQRLIARALRAAVDLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKT
NPMKGMVAAVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLLALARGGIESIVATQ
KAALAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 9e-54 58