Gene Information

Name : nrdF (ECS88_2942)
Accession : YP_002392581.1
Strain : Escherichia coli S88
Genome accession: NC_011742
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 2892569 - 2893528 bp
Length : 960 bp
Strand : +
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAACTCTCACGTATCAGCGCCATCAACTGGAACAAGATATCTGACGATAAAGATCTGGAGGTGTGGAATCGCCTGAC
CAGCAATTTCTGGCTACCAGAAAAGGTGCCACTGTCGAACGATATTCCTGCATGGCAGACATTAAGTGTCGTAGAACAAC
AACTAACAATGCGCGTTTTTACTGGCCTGACGCTGCTCGACACGCTGCAAAATGTTATCGGCGCGCCCTCGCTGATGCCC
GATGCACTCACCCCCCATGAAGAGGCGGTATTATCAAATATCAGCTTTATGGAAGCGGTTCATGCCCGCTCTTACAGTTC
AATTTTCTCGACGCTGTGCCAGACCAAAGATGTCGATGCCGCCTACGCCTGGAGCGAAGAAAACGCGCCGTTGCAGCGAA
AAGCACAGATTATTCAGCAACATTATCGCGGTGATGATCCGCTGAAAAAGAAAATCGCCAGTGTGTTTCTTGAATCTTTT
TTGTTCTATTCCGGTTTCTGGCTGCCGATGTATTTTGCCAGCCGCGGAAAGCTAACCAATACCGCAGACCTGATCCGTCT
GATTATCCGGGATGAAGCAGTCCACGGTTACTACATCGGCTATAAATATCAGAAAAACCAGGAAAAGATCTCCCAGGCAC
AGCGTGAAGAGTTGAAGAGTTTCGCCTTCGATTTGTTGCTGGAACTCTATGACAACGAGTTGCAATATACCGATGAGCTG
TACGCCGAAACCCCGTGGTCTGACGATGTAAAAGCGTTTCTCTGTTACAACGCCAATAAGGCGTTGATGAATCTGGGCTA
CGAACCGCTATTTCCCGCAGAAATGGCGGAAGTGAATCCGGCAATCCTCGCCGCGCTTTCGCCGAATGCCGATGAAAATC
ACGATTTCTTTTCCGGTTCAGGCTCTTCATATGTGATGGGAAAAGCGGTCGAAACAGAAGATGAAGACTGGAATTTCTGA

Protein sequence :
MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLSVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMP
DALTPHEEAVLSNISFMEAVHARSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
LFYSGFWLPMYFASRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNQEKISQAQREELKSFAFDLLLELYDNELQYTDEL
YAETPWSDDVKAFLCYNANKALMNLGYEPLFPAEMAEVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 2e-104 67