|
Name : vat (ECS88_0280) Accession : YP_002390114.1 Strain : Escherichia coli S88 Genome accession: NC_011742 Putative virulence/resistance : Virulence Product : Vacuolating autotransporter toxin Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG3468 EC number : - Position : 296717 - 300847 bp Length : 4131 bp Strand : - Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 12933851, 16081954; Product type e : enzyme DNA sequence : ATGAATAAAATATACGCTCTAAAATATTGTTATATTACTAACACAGTAAAGGTTGTCTCTGAACTAGCCCGAAGGGTATG TAAAGGGAGTACCCGCAGAGGAAAAAGACTTTCAGTACTTACCTCTCTGGCACTATCTGCATTACTCCCAACCGTTGCTG GTGCATCAACGGTTGGTGGCAACAATCCTTACCAGACATACCGCGACTTTGCAGAAAACAAAGGGCAGTTTCAGGCTGGC GCAACAAACATTCCTATTTTTAATAATAAAGGGGAATTAGTAGGACATCTTGATAAAGCGCCCATGGTTGATTTTAGCAG TGTGAATGTAAGCTCAAATCCCGGCGTTGCAACATTAATTAACCCGCAATATATAGCCAGTGTAAAACATAATAAAGGAT ATCAGAGCGTCAGCTTCGGTGATGGTCAGAACAGTTACCATATTGTGGATCGTAATGAACACAGTTCATCTGATCTCCAC ACACCAAGACTTGATAAGCTCGTAACTGAGGTTGCTCCGGCTACCGTAACCAGCTCATCAACAGCTGATATATTGAACCC TTCAAAATACTCGGCATTCTACAGGGCTGGTTCGGGAAGTCAGTATATTCAGGATAGTCAGGGTAAGCGACATTGGGTAA CAGGTGGGTATGGTTATCTGACAGGAGGAATACTCCCGACATCATTCTTTTATCACGGCTCAGACGGCATTCAGCTGTAT ATGGGGGGCAACATACATGATCATAGCATCCTGCCCTCTTTTGGAGAGGCCGGCGACAGTGGTTCTCCATTATTTGGCTG GAATACGGCCAAAGGGCAGTGGGAACTGGTCGGTGTTTACTCGGGAGTAGGAGGGGGGACCAATTTGATATATTCTCTTA TTCCTCAGAGTTTTCTCTCACAGATCTATTCAGAGGATAATGACGCTCCCGTCTTTTTTAATGCCTCATCCGGCGCCCCC CTGCAATGGAAATTTGACAGCAGCACCGGCACTGGCTCTCTGAAACAGGGTTCCGATGAATATGCCATGCACGGGCAAAA AGGTTCTGACCTGAACGCAGGTAAAAATCTGACATTCCTGGGACATAATGGTCAGATTGACCTGGAAAACTCTGTCACGC AGGGTGCCGGTTCACTGACATTTACTGATGACTACACTGTCACCACTTCAAACGGAAGTACCTGGACCGGGGCCGGTATT ATTGTGGACAAGGATGCCTCCGTAAACTGGCAGGTTAATGGTGTGAAAGGTGACAACCTGCATAAAATCGGCGAAGGAAC CCTGGTTGTACAGGGAACCGGTGTTAATGAGGGCGGCCTGAAAGTCGGGGATGGGACCGTTGTCCTCAATCAGCAGGCTG ACAGTTCAGGACACGTTCAGGCATTCAGTAGCGTGAATATTGCCAGCGGCCGCCCGACAGTCGTGCTGGCAGACAACCAG CAGGTTAATCCGGACAATATATCCTGGGGCTACCGGGGGGGGGTTCTGGATGTTAACGGGAATGACCTGACATTTCATAA GCTGAATGCCGCCGATTATGGCGCAACTCTCGGTAACAGCAGTGATAAAACGGCTAATATCACTCTGGATTATCAGACGC GTCCGGCAAACGTAAAAGTTAATGAATGGTCATCATCAAACAGGGGAACAGTAGGTTCATTATATATTTATAATAATCCC TATACTCATACCGTCGATTATTTTATCCTGAAAACAAGTAGTTATGGCTGGTTCCCTACCGGTCAGGTCAGTAACGAGCA CTGGGAATATGTCGGACATGACCAGAACAGTGCACAGGCGCTGCTTGCAAACAGAATTAATAATAAAGGGTATCTGTATC ATGGCAAGTTGCTGGGAAATATTAATTTCTCAAATAAAGCAACCCCGGGTACAACCGGCGCATTGGTTATGGACGGCTCA GCGAATATGTCCGGTACATTTACTCAGGAAAACGGTCGTCTGACCATTCAGGGCCACCCGGTTATCCATGCTTCAACGTC TCAGAGTATTGCAAATACAGTCTCGTCTCTGGGCGACAATTCCGTTCTGACACAGCCCACCTCATTTACACAGGATGACT GGGAGAACAGGACGTTCAGCTTTGGTTCGCTCGTGTTAAAAGATACAGACTTTGGTCTGGGCCGCAATGCCACACTGAAC ACAACCATCCAGGCAGATAACTCCAGCGTCACGCTGGGCGACAGTCGGGTATTTATCGACAAAAAAGATGGCCAGGGAAC AGCATTTACCCTTGAAGAAGGCACATCTGTTGCAACTAAAGATGCAGATAAAAGCGTCTTCAACGGCACCGTCAACCTGG ATAATCAGTCAGTGCTGAATATCAATGAGATATTCAATGGCGGAATACAGGCGAACAACAGTACCGTGAATATCTCCTCA GACAGTGCCGTTCTGGAGAACTCAACGCTGACCAGTACCGCCCTGAATCTGAACAAGGGAGCAAATGTTCTGGCCAGTCA GAGTTTTGTTTCTGACGGTCCGGTGAATATTTCTGATGCCACCCTGAGTCTGAACAGCCGTCCTGATGAGGTATCTCACA CACTTTTACCTGTATACGATTATGCCGGTTCATGGAACCTGAAGGGAGACGATGCCCGCCTGAACGTGGGGCCGTACAGT ATGTTGTCAGGTAATATCAATGTTCAGGATAAAGGGACTGTCACCCTCGGAGGGGAAGGGGAACTGAGTCCTGACCTGAC TCTTCAGAATCAGATGTTGTACAGCCTGTTTAACGGGTACCGCAATACCTGGAGCGGGAGCCTGAATGCACCGGATGCCA CCGTCAGCATGACAGACACCCAGTGGTCGATGAACGGAAACTCCACGGCAGGAAATATGAAACTTAACCGGACAATAGTC GGTTTTAACGGGGGAACATCATCGTTCACGACACTGACAACAGATAATCTGGACGCGGTTCAGTCAGCATTTGTCATGCG TACAGACCTTAACAAGGCAGACAAACTGGTGATAAACAAGTCGGCAACAGGTCATGACAACAGCATCTGGGTTAACTTCC TGAAAAAACCCTCTGACAAGGACACGCTTGATATTCCACTGGTCAGCGCACCTGAAGCGACAGCTGATAATCTGTTCAGG GCATCAACACGGGTTGTGGGATTCAGTGATGTCACCCCCACCCTTAGTGTCAGAAAAGAGGACGGGAAAAAAGAGTGGGT CCTCGATGGTTACCAGGTTGCACGTAACGACGGCCAGGGTAAGGCTGCCGCCACATTCATGCACATCAGCTATAACAACT TCATCACTGAAGTTAACAACCTGAACAAACGCATGGGCGATTTGAGGGATATTAACGGCGAAGCCGGTACGTGGGTGCGT CTGCTGAACGGTTCCGGCTCTGCTGATGGCGGTTTCACTGACCACTATACCCTGCTGCAGATGGGGGCTGACCGTAAGCA CGAACTGGGAAGTATGGACCTGTTTACCGGCGTGATGGCCACCTACACTGACACAGATGCGTCAGCAGGCCTGTACAGCG GTAAAACAAAATCATGGGGTGGTGGTTTCTATGCCAGTGGTCTGTTCCGGTCCGGCGCTTACTTTGATTTGATTGCCAAA TATATTCACAATGAAAACAAATATGACCTGAACTTTGCCGGAGCTGGTAAACAGAACTTCCGCAGCCATTCACTGTATGC AGGTGCAGAAGTCGGATACCGTTATCATCTGACAGATACGACGTTTGTTGAACCTCAGGCGGAACTGGTCTGGGGAAGAC TGCAGGGCCAAACATTTAACTGGAACGACAGTGGAATGGATGTCTCAATGCGTCGTAACAGCGTTAATCCTCTGGTAGGC AGAACCGGCGTTGTTTCCGGTAAAACCTTCAGTGGTAAGGACTGGAGTCTGACAGCCCGTGCCGGCCTGCATTATGAGTT CGATCTGACGGACAGTGCTGACGTTCACCTGAAGGATGCAGCGGGAGAACATCAGATTAATGGCAGAAAAGACGGTCGTA TGCTTTACGGTGTGGGGTTAAATGCCCGGTTTGGCGACAATACGCGTCTGGGGCTGGAAGTTGAACGCTCTGCATTCGGT AAATACAACACAGATGATGCGATAAACGCTAATATTCGTTATTCATTCTGA Protein sequence : MNKIYALKYCYITNTVKVVSELARRVCKGSTRRGKRLSVLTSLALSALLPTVAGASTVGGNNPYQTYRDFAENKGQFQAG ATNIPIFNNKGELVGHLDKAPMVDFSSVNVSSNPGVATLINPQYIASVKHNKGYQSVSFGDGQNSYHIVDRNEHSSSDLH TPRLDKLVTEVAPATVTSSSTADILNPSKYSAFYRAGSGSQYIQDSQGKRHWVTGGYGYLTGGILPTSFFYHGSDGIQLY MGGNIHDHSILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGVGGGTNLIYSLIPQSFLSQIYSEDNDAPVFFNASSGAP LQWKFDSSTGTGSLKQGSDEYAMHGQKGSDLNAGKNLTFLGHNGQIDLENSVTQGAGSLTFTDDYTVTTSNGSTWTGAGI IVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQ QVNPDNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSSDKTANITLDYQTRPANVKVNEWSSSNRGTVGSLYIYNNP YTHTVDYFILKTSSYGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGYLYHGKLLGNINFSNKATPGTTGALVMDGS ANMSGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRNATLN TTIQADNSSVTLGDSRVFIDKKDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQSVLNINEIFNGGIQANNSTVNISS DSAVLENSTLTSTALNLNKGANVLASQSFVSDGPVNISDATLSLNSRPDEVSHTLLPVYDYAGSWNLKGDDARLNVGPYS MLSGNINVQDKGTVTLGGEGELSPDLTLQNQMLYSLFNGYRNTWSGSLNAPDATVSMTDTQWSMNGNSTAGNMKLNRTIV GFNGGTSSFTTLTTDNLDAVQSAFVMRTDLNKADKLVINKSATGHDNSIWVNFLKKPSDKDTLDIPLVSAPEATADNLFR ASTRVVGFSDVTPTLSVRKEDGKKEWVLDGYQVARNDGQGKAAATFMHISYNNFITEVNNLNKRMGDLRDINGEAGTWVR LLNGSGSADGGFTDHYTLLQMGADRKHELGSMDLFTGVMATYTDTDASAGLYSGKTKSWGGGFYASGLFRSGAYFDLIAK YIHNENKYDLNFAGAGKQNFRSHSLYAGAEVGYRYHLTDTTFVEPQAELVWGRLQGQTFNWNDSGMDVSMRRNSVNPLVG RTGVVSGKTFSGKDWSLTARAGLHYEFDLTDSADVHLKDAAGEHQINGRKDGRMLYGVGLNARFGDNTRLGLEVERSAFG KYNTDDAINANIRYSF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vat | YP_851472.1 | vacuolating autotransporter | Not tested | PAI III APEC-O1 | Protein | 0.0 | 100 |
| unnamed | CAD66214.1 | putative hemoglobin protease | Not tested | PAI III 536 | Protein | 0.0 | 99 |
| vat | AAO21903.1 | vacuolating autotransporter toxin | Virulence | Not named | Protein | 0.0 | 98 |
| pic | NP_838464.1 | serine protease precurser | Virulence | SHI-1 | Protein | 0.0 | 49 |
| she | AAB58244.1 | mucinase | Virulence | SHI-1 | Protein | 0.0 | 48 |
| pic | NP_708747.3 | serine protease | Not tested | SHI-1 | Protein | 0.0 | 48 |
| pic | AAK00464.1 | Pic | Virulence | SHI-1 | Protein | 0.0 | 48 |
| unnamed | CAC39286.1 | hypothetical protein | Not tested | LPA | Protein | 0.0 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| vat | YP_002390114.1 | Vacuolating autotransporter toxin | VFG0904 | Protein | 0.0 | 99 |
| vat | YP_002390114.1 | Vacuolating autotransporter toxin | VFG1689 | Protein | 0.0 | 99 |
| vat | YP_002390114.1 | Vacuolating autotransporter toxin | VFG0903 | Protein | 0.0 | 49 |
| vat | YP_002390114.1 | Vacuolating autotransporter toxin | VFG0635 | Protein | 0.0 | 48 |
| vat | YP_002390114.1 | Vacuolating autotransporter toxin | VFG0861 | Protein | 0.0 | 48 |
