Gene Information

Name : ECS88_0237 (ECS88_0237)
Accession : YP_002390071.1
Strain : Escherichia coli S88
Genome accession: NC_011742
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 251028 - 253787 bp
Length : 2760 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor

DNA sequence :
ATGATCCAGATTGATTTAGCCACGCTCGTAAAGCGGCTTAACCCCTTTGCAAAACAGGCGCTGGAAATGGCTGCCTCGGA
GTGTATGAGCCAGCAGGCCAGTGAGATCACCGTTGCCCATGTGCTGTTACAGATGCTGGCAATCCCGCGCAACGACGTAA
GGGTGATTGCCGAACGCACAGGCATCAGTGCGGAGGATTTACGCCAGGCGCTGACCGTGGAGAGTTATCCCGGTGGACGT
TCCGCCGAAGGCTATCCCAGCTTCTCCCCGATGCTGATCGAATGGCTCAAGGAGTCATGGCTGCTGGCCTCAGCCCAGAT
GCAGCACAGCGAACTGCGCAGCGGCGTCCTGCTGCTTACTCTGCTGCATTCACCGCTGCGCTATATTCCACCCGCTGCTG
CCCGTCTGCTGACGGCCATAAACCGCGACCAGTTACAGCAGGATTTCGCAGCATGGACAAAAGAATCCGCCGAATCCGTG
GATCTGGCTGGCGGGCAAACGCCCCGCGCAACGGAAACCGGCGACACCCTGCTTGCCCGCTACGCCAAAAACATGACCGC
AGACGCCCGTAACGGCAGGCTTGACCTGGTACTGTGCCGCAACTATGAAATCGACCTGATGATCGACATTCTCTGCCGCC
GCCGTAAAAACAATCCGGTGGTAGTGGGCGAAGCAGGCGTGGGTAAAAGCGCGCTGATTGAAGGGCTGGCGCTGCGCATC
GTGGCAGGCCAGGTGCCGGACAAGCTGAAAAACACCGATATCATGACCCTTGACCTGGGCGCATTGCAGGCCGGTGCGTC
GGTGAAAGGTGAGTTTGAAAAACGCTTCAAGGGGCTGATGGCGGAGGTCATTTTCTCCCCGGTGCCGGTCATTCTGTTTA
TCGACGAAGCACATACCCTGATTGGCGCGGGCAACCAGCAGGGCGGGCTGGATATATCCAACCTGCTCAAACCAGCGCTG
GCGCGCGGCGAGCTGAAAACCATCGCCGCCACCACCTGGAGCGAGTACAAAAAATATTTCGAGAAAGATGCAGCTTTGTC
GCGCCGCTTCCAGTTAGTGAAGGTCAGCGAACCCAACGCTGCCGAAGCCACCATTATTCTGCGCGGTTTGTCGGCGGTCT
ATGAACAATCTCACGGCGTGCTGATTGATGATGACGCCTTGCAGGCCGCTGCGACACTGAGCGAGCGTTATCTCTCCGGG
CGTCAGTTGCCGGACAAAGCCATTGATGTGCTGGACACCGCCTGCGCCCGTGTGGCCATCAACCTGTCATCGCCGCCAAA
ACAAATCTCGGCACTGACCACCCTGAGCCACCAGCAGGAGGCAGAAATTCGCCAGCTTGAGCGCGAGCTTCGCATCGGGC
TGCGTACCGACACCTCACGAATGACTGAGGTGTTGGAGCAGTATGATGAAACGCTGTCGGCGCTGGACGAACTGGAAGTC
GCCTGGCAGCAGCAGACGCTGGTACAGGAAATTATCGCGCTGCGCCAGCAGTTACTGGGCGTGGCAGAAGACGACGTTGC
GTCGTTGCCGGACGCAGATGCCGTGGAGGATACGCCGCCAGAGGCAGAACAGGATAGTACCGATGCCGAATCGGCTGATG
ATGCAGGCAGCGTACAGCCGGAAGAGACCGCTGAAACAGTTTCCCCGGTACAACGGCTGGCACAACTCACTGCCGAACTG
GACGCCCTGCATAACGACCAGTTGCTGGTTTCCCCGCATGTCGATAAAAAACAGATTGCAGCGGTGATTGCTGAATGGAC
CGGCGTGCCGCTTAACCGCCTGTCACAGAATGAGATGTCGGTCATCACCGACCTGCCGGTATGGCTCGGCGGCACCATCA
AGGGCCAGGACCTGGCGATTGCCAGCCTGCATAAACACCTGCTGACCGCACGCGCCGACCTGCGCCGTCCGGGACGCCCG
CTTGGTGCGTTCCTGCTGGCTGGCCCCAGCGGCGTGGGTAAAACCGAAACCGTCCTGCAACTGGCGGAACTGCTCTATGG
CGGACGTCAATACCTGACCACCATCAATATGTCTGAGTTCCAGGAGAAACACACCGTTTCGCGGCTGATTGGCTCTCCTC
CGGGTTATGTCGGCTACGGTGAAGGCGGCGTACTGACCGAAGCGATTCGCCAGAAACCGTACTCGGTGGTGCTGCTCGAT
GAAGTAGAAAAAGCGCACCCGGATGTACTCAACCTGTTCTACCAGGCGTTTGACAAGGGCGAGATGGCAGACGGTGAAGG
CCGCCTGATTGACTGTAAAAATATCGTTTTCTTCCTGACCTCCAACCTTGGCTACCAGGTGATTGTCGAACACGCCGATG
ACCCGGAAACCATGCAGGAAGCCCTCTATCCGGTGCTGGCGGACTTCTTTAAACCTGCTCTGCTGGCGCGCATGGAAGTG
GTGCCTTACCTACCGCTGTCGAAAGAGACGCTCGCTACCATTATTGCCGGGAAACTGGCCCGCCTGGATAACGTGCTGCG
CAGCCGCTTTGGCGCGGACGTGATTATTGGGCCGGAAGTGACGGACGAAATCATGAGCCGCGTCACCCGCGCGGAAAACG
GCGCGAGGATGCTGGAATCGGTTATCGACGGCGACATGCTGCCGCCGCTCTCGCTGCTGCTGTTGCAGAAAATGGCGGCC
AACACGGCGATTGCCCGGATTCGCCTGTCGGCGGCAGACGGTGCGTTCACGGCAGATGTGGAAGATGCGCTGCCTGATGA
TGCCGTGACACCGCAAACAGAGGACGAAACGGTTTTATGA

Protein sequence :
MIQIDLATLVKRLNPFAKQALEMAASECMSQQASEITVAHVLLQMLAIPRNDVRVIAERTGISAEDLRQALTVESYPGGR
SAEGYPSFSPMLIEWLKESWLLASAQMQHSELRSGVLLLTLLHSPLRYIPPAAARLLTAINRDQLQQDFAAWTKESAESV
DLAGGQTPRATETGDTLLARYAKNMTADARNGRLDLVLCRNYEIDLMIDILCRRRKNNPVVVGEAGVGKSALIEGLALRI
VAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEKRFKGLMAEVIFSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKPAL
ARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEPNAAEATIILRGLSAVYEQSHGVLIDDDALQAAATLSERYLSG
RQLPDKAIDVLDTACARVAINLSSPPKQISALTTLSHQQEAEIRQLERELRIGLRTDTSRMTEVLEQYDETLSALDELEV
AWQQQTLVQEIIALRQQLLGVAEDDVASLPDADAVEDTPPEAEQDSTDAESADDAGSVQPEETAETVSPVQRLAQLTAEL
DALHNDQLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLPVWLGGTIKGQDLAIASLHKHLLTARADLRRPGRP
LGAFLLAGPSGVGKTETVLQLAELLYGGRQYLTTINMSEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLD
EVEKAHPDVLNLFYQAFDKGEMADGEGRLIDCKNIVFFLTSNLGYQVIVEHADDPETMQEALYPVLADFFKPALLARMEV
VPYLPLSKETLATIIAGKLARLDNVLRSRFGADVIIGPEVTDEIMSRVTRAENGARMLESVIDGDMLPPLSLLLLQKMAA
NTAIARIRLSAADGAFTADVEDALPDDAVTPQTEDETVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 0.0 99
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 0.0 99
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 6e-122 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECS88_0237 YP_002390071.1 ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity VFG2084 Protein 0.0 57
ECS88_0237 YP_002390071.1 ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity VFG2076 Protein 1e-135 41