Gene Information

Name : actP (ECIAI1_4300)
Accession : YP_002389539.1
Strain : Escherichia coli IAI1
Genome accession: NC_011741
Putative virulence/resistance : Resistance
Product : acetate permease
Function : -
COG functional category : R : General function prediction only
COG ID : COG4147
EC number : -
Position : 4374361 - 4376010 bp
Length : 1650 bp
Strand : -
Note : member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake

DNA sequence :
ATGAAAAGAGTTCTGACGGCGCTTGCCGCCACACTCCCTTTCGCAGCTAACGCCGCGGATGCTATTAGCGGGGCCGTAGA
GCGCCAGCCAACGAACTGGCAGGCGATTATTATGTTCCTGATTTTCGTCGTGTTTACGCTCGGCATTACCTACTGGGCAT
CAAAACGCGTACGTTCTCGTAGCGACTACTACACCGCAGGCGGCAATATCACTGGCTTCCAGAACGGGCTGGCGATTGCC
GGGGACTATATGTCCGCCGCCTCATTCTTGGGGATCTCCGCGCTGGTGTTTACCTCCGGCTATGACGGCTTAATTTACTC
GCTGGGCTTCCTGGTGGGCTGGCCGATCATTTTGTTCCTGATTGCCGAACGTCTGCGTAACCTGGGGCGCTACACCTTTG
CCGATGTGGCCTCTTACCGTCTGAAACAAGGGCCGATTCGTATTCTTTCGGCCTGTGGTTCTCTGGTGGTGGTGGCGCTT
TACCTTATCGCCCAGATGGTGGGCGCAGGTAAACTGATCGAGCTGCTGTTTGGCCTTAACTATCACATTGCGGTGGTGCT
GGTCGGCGTGCTGATGATGATGTACGTCCTGTTCGGCGGCATGCTGGCGACCACTTGGGTACAGATTATCAAAGCCGTGC
TGTTGCTGTTCGGTGCCAGCTTTATGGCCTTTATGGTGATGAAACACGTCGGCTTTAGCTTCAACAATCTGTTCAGTGAA
GCGATGGCGGTACACCCGAAAGGTGTCGACATCATGAAGCCGGGCGGGCTGGTGAAAGATCCGATCTCCGCGCTCTCTCT
GGGTCTGGGACTGATGTTTGGTACGGCGGGCTTGCCGCACATTCTGATGCGCTTCTTTACAGTCAGCGATGCCCGCGAAG
CACGTAAGAGCGTGTTCTACGCCACCGGGTTTATGGGCTACTTCTATATTCTGACCTTTATTATCGGCTTCGGCGCGATC
ATGCTGGTTGGTGCGAATCCGGAATATAAAGACGCGGCGGGCCATCTGATTGGTGGTAACAACATGGCGGCCGTTCACCT
GGCGAATGCAGTGGGCGGCAACCTGTTCCTCGGTTTTATTTCAGCGGTTGCTTTTGCCACCATTCTTGCGGTGGTTGCTG
GTCTGACGCTGGCGGGCGCATCAGCGGTTTCGCATGACCTGTACGCTAACGTCTTCAAAAAAGGCGCGACCGAACGTGAA
GAACTGCGGGTATCGAAAATCACCGTGCTGATTTTAGGTGTGATTGCCATTATCCTCGGCGTGCTGTTTGAGAATCAGAA
CATCGCCTTCATGGTAGGCCTGGCGTTTGCCATCGCAGCGAGCTGTAACTTCCCGATCATTCTGCTTTCTATGTACTGGT
CGAAACTGACCACTCGTGGCGCGATGATGGGTGGCTGGCTGGGGCTGATTACCGCAGTGGTACTGATGATCCTCGGCCCG
ACGATTTGGGTACAGATCCTTGGTCACGAAAAAGCCATCTTCCCGTATGAATACCCGGCGCTGTTCTCTATCAGCGTGGC
ATTCCTCGGCATCTGGTTTTTCTCGGCAACCGATAACTCAGCGGAAGGTGCGCGCGAGCGTGAACTGTTCCGTGCACAGT
TTATCCGCTCCCAGACCGGCTTTGGCGTTGAGCAAGGCCGCGCACATTAA

Protein sequence :
MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVVFTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIA
GDYMSAASFLGISALVFTSGYDGLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFGASFMAFMVMKHVGFSFNNLFSE
AMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTAGLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAI
MLVGANPEYKDAAGHLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVFKKGATERE
ELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLSMYWSKLTTRGAMMGGWLGLITAVVLMILGP
TIWVQILGHEKAIFPYEYPALFSISVAFLGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AAK01502.1 putative amino acid transport protein Not tested PAGI-1 Protein 5e-123 58
cur_1523 YP_001800917.1 transporter Not tested Not named Protein 5e-67 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
actP YP_002389539.1 acetate permease BAC0564 Protein 0.0 99
actP YP_002389539.1 acetate permease BAC0570 Protein 8e-135 65