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Name : lpfC (ECIAI1_3709) Accession : YP_002389017.1 Strain : Escherichia coli IAI1 Genome accession: NC_011741 Putative virulence/resistance : Virulence Product : outer membrane usher protein lpfC Function : - COG functional category : N : Cell motility COG ID : COG3188 EC number : - Position : 3777656 - 3780187 bp Length : 2532 bp Strand : - Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14977923; Product type m : membrane component DNA sequence : ATGCATTGGATGCATTTACCTCTCTATCACTACAGAGCGCATTTTTCCTTCTCTCTGCTGGCATTAACGATTGCCAGCTC GTTACCTGCGTATGGCGGAAAATTTAACCCTAAATTTCTCGAAAACGTTCAGGGTATCGATCAACACATCGACTTGTCGG TATACGACTCACCTGTCGGCCAGCAAATCCCCGGTAAATACCGGGTTTCGGTGTTTGTAAACGAAGAAAAAATGGCTTCC CGGACGCTGGATTTTAGTACCGCCAGCGAAGCGAAACGCAAAGCCAGCGGTGAGTCGCTTATGCCTTGCCTTAGCCGGGT GCAACTGGAAGAAATGGGCGTGCGCGTTGACAGCTTTCCGGCGCTGAAGATGTCACCACCAGAAGCCTGCGTAGCGTTTG ATGAAATCATTCCCCAGGCCACCAGCCGCTTTGATTTTAATACTCAGACGCTGCATCTTTCCTTTCCACAGGCGGCAATG ATGATGACCGCTCGCGGCACGGTTGATCCTTCTCGCTGGGACGAAGGAATACCTGCGCTGTTGCTGGATTACAGCTTTAG TGGCAGCAATGGACGCAATGAAGGTACAGGTTCATCTTCAGATTCGACCAGTGACAGTTATTACCTGAACCTGCGCAGCG GTTTGAACGTTGGTCCGTGGCGTTTACGTAATAACAGTATCTGGAACCGTACCGATGGCAAAAACCAATGGGATAACGTT GGTACATCGTTAAACCGGGCAATTATTCCACTTAAATCACAGATAACTCTGGGTGATACCGCCACGCCTGGCGAGATTTT TGATAGCGTACAAATGCGTGGGGCGTTACTGGCATCCGACGATGAAATGTTGCCGGACAGCCAGCGTGGCTTTGCTCCGG TAGTGCGCGGCATCGCCAAAAGCAACGCTGAAGTGAGTATCGAACAGAACGGCTATGTCATTTATCGCACTTTTGTTCAG CCGGGTGCATTTGAGATTAACGATCTCTACGCAACCTCCGGCAGCGGCGACCTGACGGTGATCATTAAAGAAGCCGACGG AAGTGAACAACGTTTTATCCAGCCGTTTTCGGCGGTGGCGATTTTCCAGCGTGAAGGGTATCTGAAATACAGTCTGGCTG CCGGTGAATATCGTGCTGGTAATTACGACAGCGATAAACCACATTTCGGGCAGTTTACCGCCATGTACGGCTTGCCGTGG GGTATGACCGCCTACGGTGGTGCATTGTTGTCGGCAGATTACAACGCTTTAGCTCTGGGCCTGGGGAAAAACTTCGGTAC CATTGGCGCAGTATCGGTGGATGTCACTCAGGCGAAAAGTCAGTTACGCAACAATGAAAAAGAGGAAGGCCAGTCTTATC GCTTCCTCTATTCGAAAAGTTTTGAGGGTGGCACTGACCTGCGTCTGTTGGGCTACAAATACTCAACCAGCGGCTACTAC ACCTTCCAGGAAGCAACTGATGTTCGCAGTGACGCCGACAGTGATTACCGCCGTTATCACAAGCGCAGCCAGATACAGGG CAATATTACCCAGCAACTGGGAGACTACGGCTCGGTTTATTTCAATATGACGCAGCAGGATTACTGGAACGTTGACGGTA AGGAAAACTCCTTAAGCGCCGGTTATCACGGTCACATTGGTCGGGTGAATTACAGCGTGGCCTATACCTGGACGAGAAGT CCGGAATGGGAAGAAGACGATCGCTTGTGGTCATTCAGTGTTTCCATCCCTCTGGGGGGCGCGTGGAGCAGTTATCGCAT GACTACCGACCAGAATGGCAAGACGTCGCAACAGGCCTCTGTTAGCGGCACGTTACTGGAAGATCGTAACCTGAGCTATA ACGTTCAGCAGGGTTACACCAGTAATGGCGTAGGCTACAGTGGCAGCGTCAACATGGGGTATATGGGTGGCTCTGGTAAC ATTGACGTAGGCTATAACTATTCTAAAGATAACCAACAGGTTAACTATGGCGTGCGCGGCGGTGTCATCGTTCACAGTGA AGGTATAACGCTTTCGCAGCCTTTAGGCGAAAGTCTGGCGATTGTTTCTGCACCGGGCGCGCGTGGTGGACATGTGGTTA ACAGCAGCGGCGTAGAAGTTGACTGGATGGGCAACGCCGTGGTGCCTTATCTCACACCATATCGTGAAACCATTGTGGAA TTGCGTAGCGACACGTTGGGGCAAAACGTTGAACTACAGGAAGCGTTCCAGAAAGTCGTGCCTACTCGTGGTGCAGTTGT GCGTTCCCGCTTTGATACCCGCGTCGGTTACCGTGTGCTGATGAGCTTAAAACAGGCGAATGGCAACGCAGTACCGTTTG GTGCAACCGCAGCGTTAATTGATGAGAGCAAACCTGCCAGCAGCATTGTGGGTGAAGAAGGACAGCTTTATATCAGCGGG ATGCCAGAAGAGGGCGAATTGCAGGTGAGCTGGGGGAACGAGCAGGCGCAACGTTGCCGTGTGCCATTCCGCTTGCCAGA GAACAAGGACAATGCGGCTATCGTGATGGTTAATGCGGTATGCGAGAAATAA Protein sequence : MHWMHLPLYHYRAHFSFSLLALTIASSLPAYGGKFNPKFLENVQGIDQHIDLSVYDSPVGQQIPGKYRVSVFVNEEKMAS RTLDFSTASEAKRKASGESLMPCLSRVQLEEMGVRVDSFPALKMSPPEACVAFDEIIPQATSRFDFNTQTLHLSFPQAAM MMTARGTVDPSRWDEGIPALLLDYSFSGSNGRNEGTGSSSDSTSDSYYLNLRSGLNVGPWRLRNNSIWNRTDGKNQWDNV GTSLNRAIIPLKSQITLGDTATPGEIFDSVQMRGALLASDDEMLPDSQRGFAPVVRGIAKSNAEVSIEQNGYVIYRTFVQ PGAFEINDLYATSGSGDLTVIIKEADGSEQRFIQPFSAVAIFQREGYLKYSLAAGEYRAGNYDSDKPHFGQFTAMYGLPW GMTAYGGALLSADYNALALGLGKNFGTIGAVSVDVTQAKSQLRNNEKEEGQSYRFLYSKSFEGGTDLRLLGYKYSTSGYY TFQEATDVRSDADSDYRRYHKRSQIQGNITQQLGDYGSVYFNMTQQDYWNVDGKENSLSAGYHGHIGRVNYSVAYTWTRS PEWEEDDRLWSFSVSIPLGGAWSSYRMTTDQNGKTSQQASVSGTLLEDRNLSYNVQQGYTSNGVGYSGSVNMGYMGGSGN IDVGYNYSKDNQQVNYGVRGGVIVHSEGITLSQPLGESLAIVSAPGARGGHVVNSSGVEVDWMGNAVVPYLTPYRETIVE LRSDTLGQNVELQEAFQKVVPTRGAVVRSRFDTRVGYRVLMSLKQANGNAVPFGATAALIDESKPASSIVGEEGQLYISG MPEEGELQVSWGNEQAQRCRVPFRLPENKDNAAIVMVNAVCEK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| fim2D | AFH78429.1 | putative fimbrial usher protein | Virulence | KpGI-5 | Protein | 4e-163 | 43 |
| lpfC | YP_006098365.1 | fimbrial outer membrane usher protein | Not tested | Tn2411 | Protein | 1e-139 | 41 |
| sfaF | CAC16953.2 | SfaF protein | Virulence | PAI III 536 | Protein | 1e-163 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| lpfC | YP_002389017.1 | outer membrane usher protein lpfC | VFG0454 | Protein | 0.0 | 74 |
| lpfC | YP_002389017.1 | outer membrane usher protein lpfC | VFG0876 | Protein | 1e-167 | 44 |
| lpfC | YP_002389017.1 | outer membrane usher protein lpfC | VFG0446 | Protein | 5e-155 | 42 |
| lpfC | YP_002389017.1 | outer membrane usher protein lpfC | VFG1645 | Protein | 7e-164 | 41 |
| lpfC | YP_002389017.1 | outer membrane usher protein lpfC | VFG0912 | Protein | 2e-163 | 41 |
