Gene Information

Name : arsB (ECIAI1_3649)
Accession : YP_002388964.1
Strain : Escherichia coli IAI1
Genome accession: NC_011741
Putative virulence/resistance : Resistance
Product : arsenite/antimonite transporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 3712631 - 3713920 bp
Length : 1290 bp
Strand : +
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15004242, 95355341, 1535622, 7721697; Product type t : transporter

DNA sequence :
ATGTTACTGGCAGGCGCTATCTTTGTCCTGACCATCGTATTGGTTATCTGGCAGCCGAAAGGTTTAGGCATCGGCTGGAG
TGCAACGCTCGGCGCAGTACTGGCGTTAGTTACGGGCGTGGTCCATCCGGGTGATATTCCGGTGGTGTGGAATATCGTCT
GGAACGCGACGGCTGCGTTTATCGCCGTCATTATCATCAGCCTGCTGCTGGATGAGTCCGGCTTTTTTGAATGGGCGGCG
CTGCACGTCTCACGCTGGGGTAATGGTCGTGGTCGCTTGCTGTTTACCTGGATTGTCCTGCTCGGTGCTGCCGTTGCCGC
CCTGTTTGCCAATGATGGCGCGGCGCTTATTTTGACACCGATTGTCATCGCCATGCTGCTGGCTTTAGGGTTCAGTAAAG
GCACTACGCTGGCGTTCGTGATGGCGGCCGGATTCATTGCCGATACCGCCAGCCTGCCGCTTATTGTCTCCAACCTGGTG
AATATCGTTTCCGCTGATTTCTTTGGCCTCGGCTTTCGCGAATACGCCTCGGTGATGGTGCCGGTGGATATCGCCGCGAT
TGTTGCCACGCTGGTGATGTTACATCTCTATTTTCGCAAAGATATTCCGCAGAACTACGATATGGCGCTGCTGAAATCTC
CCGCAGAAGCGATCAAAGATCCTGCTACGTTCAAAACTGGCTGGGTTGTTTTACTGCTTCTGCTGGTGGGATTTTTCGTC
CTGGAACCGCTCGGCATTCCGGTGAGCGCCATTGCAGCTGTGGGCGCGCTGATATTATTTGTCGTCGCTAAACGCGGTCA
TGCGATTAATACGGGTAAAGTCCTGCGCGGTGCCCCCTGGCAGATTGTCATCTTCTCGCTCGGCATGTATCTGGTGGTTT
ATGGCCTGCGCAATGCCGGATTAACGGAATATCTTTCTGGCGTACTCAACGTGCTGGCGGATAACGGCCTGTGGGCCGCG
ACGCTCGGCACCGGATTCCTCACCGCCTTCCTCTCTTCTATTATGAACAATATGCCGACGGTACTGGTTGGCGCGTTGTC
CATTGATGGCAGCACGGCATCTGGCGTTATCAAAGAAGCGATGGTTTATGCCAATGTGATTGGCTGCGATTTGGGACCGA
AAATTACCCCAATTGGTAGCCTGGCTACGCTACTCTGGCTGCACGTACTTTCGCAGAAGAATATGACTATCAGCTGGGGA
TATTACTTCCGTACAGGGATTATCATGACCCTGCCTGTGCTGTTTGTGACGCTGGCTGCGCTGGCGCTACGTCTCTCTTT
CACTTTGTAA

Protein sequence :
MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA
LHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFV
LEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAA
TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG
YYFRTGIIMTLPVLFVTLAALALRLSFTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 7e-157 92
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 1e-95 59
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 4e-95 59
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 4e-99 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_002388964.1 arsenite/antimonite transporter BAC0578 Protein 3e-161 94
arsB YP_002388964.1 arsenite/antimonite transporter BAC0576 Protein 2e-160 94
arsB YP_002388964.1 arsenite/antimonite transporter BAC0031 Protein 2e-156 91
arsB YP_002388964.1 arsenite/antimonite transporter BAC0577 Protein 5e-155 90
arsB YP_002388964.1 arsenite/antimonite transporter BAC0575 Protein 4e-100 60
arsB YP_002388964.1 arsenite/antimonite transporter BAC0574 Protein 9e-97 60