Gene Information

Name : eprK (ECIAI1_2971)
Accession : YP_002388318.1
Strain : Escherichia coli IAI1
Genome accession: NC_011741
Putative virulence/resistance : Virulence
Product : putative Type III secretion system lipoprotein EprK
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG4669
EC number : -
Position : 3047862 - 3048596 bp
Length : 735 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12791847; Product type pm : putative membrane component

DNA sequence :
ATGAAATATATATCATTATTATTGTTTATCCTGCTGTTGTGCGGCTGCAAGCAGCAGGAATTATTGAACCATCTTGATCA
ACAGCAAGCTAATGATGTCCTTGCTGTTTTACAAAGACATAATATTAATGCTGAAAAGAAGGATCAAGGCAAAACAGGAT
TTTCAATATTTGTCGAACCAACGGATTTTGCTTCTGCGGTGGATTGGCTAAAAATCTACAATCTACCGGGTAAGCCTGAT
ATTCAAATATCGCAGATGTTCCCTGCAGATGCACTCGTTTCATCTCCACGAGCGGAAAAAGCAAGGCTATATTCTGCTAT
TGAGCAGCGGTTAGAGCAATCTCTCAAAATTATGGATGGCATTATTTCTTCGAGAGTACATGTTAGTTACGATGTTGATA
ATGGCGATAGTGGTAAAACTGCTTTACCAATTCATATTTCTGTACTTGCAGTATATGAAAAAGATATCAACCCAGAAATA
AAAATAAATGATATCAAGAGATTTATTGTTAATAGCTCTGCAAGCGTACAATATGAAAATATTTCTGTTGTATTGTCAAA
ACGAAGAGACATTATTGAGCAAGCACCAACATATGAAATTAGCGAACCTGTTTTTGCTTATGATAAGGCTATGCCGGTTT
CTATCTTACTTGCATTAATATCCGTAGCGACTTGCTGGCTGTTATGGAAGTATAGGGCCATTCTAACTAATTTAGTCAGG
TTGAAAATTAAGTAG

Protein sequence :
MKYISLLLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIFVEPTDFASAVDWLKIYNLPGKPD
IQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDGIISSRVHVSYDVDNGDSGKTALPIHISVLAVYEKDINPEI
KINDIKRFIVNSSASVQYENISVVLSKRRDIIEQAPTYEISEPVFAYDKAMPVSILLALISVATCWLLWKYRAILTNLVR
LKIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
eprK AAZ31284.1 EprK Virulence ETT2 Protein 2e-106 100
ECs3716 NP_311743.1 EprK Not tested LIM Protein 6e-105 99
prgK NP_461792.1 needle complex inner membrane lipoprotein Virulence SPI-1 Protein 4e-53 55
prgK NP_457265.1 pathogenicity 1 island effector protein Virulence SPI-1 Protein 1e-53 55
prgK NP_806474.1 pathogenicity island 1 effector protein Virulence SPI-1 Protein 1e-53 55
prgK YP_217790.1 cell invasion protein Virulence SPI-1 Protein 4e-53 55
prgK AAS66872.1 PrgK Virulence SSR-2 Protein 3e-50 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
eprK YP_002388318.1 putative Type III secretion system lipoprotein EprK VFG0533 Protein 2e-53 55
eprK YP_002388318.1 putative Type III secretion system lipoprotein EprK VFG0998 Protein 8e-43 45
eprK YP_002388318.1 putative Type III secretion system lipoprotein EprK VFG1787 Protein 6e-36 42