Gene Information

Name : yfcS (EFER_0827)
Accession : YP_002382000.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Virulence
Product : periplasmic pilus chaperone
Function : -
COG functional category : N : Cell motility
COG ID : COG3121
EC number : -
Position : 845751 - 846503 bp
Length : 753 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor

DNA sequence : 
ATGTATACATTGACTCGCTCTGCAAAAAGAGTTGCCCCTGCGCTGGCGCTGCTGGTGGCGGCCGCCAGTTTTACCACCCA
CGCATCGGTGACACCCGACCGTACACGCCTGGTCTTCAATGAAGGCGACAAATCTATCAGCGTCACGTTGCGCAATAACG
ACCCGAAGCAGCCCTACCTGGCGCAAAGCTGGATGGAGGACGAAAAGGGCAACAAAATCAGCTCGCCACTTACGGTACTG
CCGCCGGTACAGCGTATTGATGCGATGATGAATGGTCAGGTAAAAGTCCAGGGAATGCCGGATATCAACAAGTTACCGGC
CGATCGTGAGAGCATGTTCTACTTTAACGTGCGTGAAATCCCGCCAAAATCGAACAAACCTAATACGCTGCAAATTGCCC
TGCAAACGCGTATCAAATTGTTCTGGCGACCCAAGGCACTGGCAAAAATTGACATGAGGGAGCCGTGGCAGCACAAGGTG
ACGTTAACCCGCAATGGACAGGCGTTCACCGTCAATAACCCCACGCCCTATTACGTGATTATCAGCAATGCCAGCACACA
GAAAAATGGTAATCCGGCAGCCGGGTTTACGCCGCTGGTCATGCCGCCGAAATCGTCCGCACCGTTGAATGTGAAGATGG
ACACTGTGCCGGTGCTGACTTACGTCAACGACTACGGCGCGCGATTGTCGCTGAACTTTAAATGCAATGGCAATAATTGC
CAGGTGGATGCAGAGCAAAGCCGCAAAGGCTGA

Protein sequence : 
MYTLTRSAKRVAPALALLVAAASFTTHASVTPDRTRLVFNEGDKSISVTLRNNDPKQPYLAQSWMEDEKGNKISSPLTVL
PPVQRIDAMMNGQVKVQGMPDINKLPADRESMFYFNVREIPPKSNKPNTLQIALQTRIKLFWRPKALAKIDMREPWQHKV
TLTRNGQAFTVNNPTPYYVIISNASTQKNGNPAAGFTPLVMPPKSSAPLNVKMDTVPVLTYVNDYGARLSLNFKCNGNNC
QVDAEQSRKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
papD NP_755464.1 PapD protein Virulence PAI I CFT073 Protein 3e-43 43
prfD CAD42028.1 PrfD protein Virulence PAI II 536 Protein 5e-49 43
papD AAL67413.1 PapD Virulence PAI II CFT073 Protein 1e-48 43
papD YP_854253.1 pilus assembly protein chaperone PapD Virulence PAI I APEC-O1 Protein 2e-48 43
papD_2 NP_757033.1 PapD protein Virulence PAI II CFT073 Protein 2e-48 43
papD YP_002414014.1 Chaperone protein PapD Not tested Not named Protein 2e-48 43
papD AAZ04423.1 P pilus chaperone Virulence PAI I APEC-O1 Protein 2e-48 43
pixD CAE85158.1 PixD protein Not tested PAI V 536 Protein 2e-49 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfcS YP_002382000.1 periplasmic pilus chaperone VFG0885 Protein 1e-43 43
yfcS YP_002382000.1 periplasmic pilus chaperone VFG1547 Protein 3e-49 43
yfcS YP_002382000.1 periplasmic pilus chaperone VFG0896 Protein 9e-49 43