Gene Information

Name : EFER_0826 (EFER_0826)
Accession : YP_002381999.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Virulence
Product : outer membrane usher protein yfcU
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 843083 - 845731 bp
Length : 2649 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter

DNA sequence :
ATGGATACGTGTATGCCTGACCATTCTCTTTTCCGCTTACGGGCGCTTCCTTGGTGCGTTGCCGTGGCCATCTCTGGATG
CCATATCAATGCCTGGGCTGATGAAGATATTCAGTTTGATTCCCGTTTTCTGGAATTAAAAGGCGACACGAAAATCGATT
TAAAACGCTTTTCAAGCCAGGGTTATGTTGAGCCAGGTAAATACAGTTTACAGGTTGAGGTCAATAAACAGCCGTTACCC
GGTGAATATGATATTTACTGGTATGCAACAGAAAATGACGCCAATAAGACTTATGCCTGTCTGTCGCCAGACCTGGCGGC
ACAGCTTGGTTTTAAAGAAGACATTGCGAACAATTTGCAATGGGTTCTCGACGGTAAATGCCTCAAGCCAGGCCAACTTG
ACGGTCTGGAAATGCGCGCTGATTTAAGCCAGTCCGCACTCCTTATCACCTTACCGCAGGCTTATCTTGAATACAGCGAT
GTCGACTGGGACCCTCCCTCGCGCTGGGATGATGGCATCTCAGGTTTAATTGCCGATTACAGCATCAATGCCCAAACCCG
ACATGAAGAAAATAGCGGTGATGACAGCAACGATATCAGCGGCAACGGTACGGTTGGCGTTAACCTCGGGCCGTGGCGCT
TGCGAGCCGACTGGCAGAGCGATTATCAGCATACCCGCAGTAATGATAAAGAGACGGAAGACAGCACCGAAAGAAACTGG
GACTGGAGCCGTTACTATGCCTGGCGCGCGTTACCGAGCCTGAAAGCCAAACTGGCACTCGGTGAAGATTACCTCGATTC
CGATATTTTCGATGGCTTTAACTACATCGGCGGTAGTATCAGTACTGACGATCAAATGCTGCCGCCGAATCTGCGCGGCT
ATGCTCCAGATATTTCCGGCGTGGCCCATACGGCGGCGAAAGTCACCGTTAGCCAGGCCGGGCGTATAATTTATGAAACC
CAGGTGCCAGCCGGGCCATTCCGTATCCAGGATCTTGCCGATTTTAGCTCTGGTACGCTGCATGTGCGCATTGAAGAGGT
GAACGGTCAGGTGCAGGAGTATGACATCAGCACTGCCTCCATGCCGTTCCTGACTCGCCCGGGCCAGGTGCGCTACAAAA
TTATGATGGGGCGACCACAGGAGTGGGGGCACCATGTGCAAGGCGGGTTCTTTTCCGGTGGCGAAGCGTCCTGGGGGATA
GCAAACGGCTGGTCACTGTATGGCGGGGCGCTTGGCGATGAAAATTACCAGTCAGCCGCGCTTGGGATTGGTCGCGATCT
CTCCATTTTCGGTGCGATGGCCTTTGATATCACCCACTCGCATACCCGACTTGACGATTCGACCGCTTACGGAAAAAGCA
CTCTCGACGGTAACTCTTTCAGAGTCAGTTATTCCAAAGACTTTGATGAACTCAACAGCCGCGTCACCTTCGCCGGATAC
CGCTTCTCGGAAGAGAACTATATGACCATGAGTGAGTATCTGGACGCGAATGACAGCGCAATGGTCCGCTCAGGCAATGA
TAAAGAGATGTACACCGCCACCTATAACCAGAACTTTAGAGATGCCGGTGTTTCTGTTTACCTGAACTATACGCGTCACA
CCTACTGGGATCGTGAGGAACAGACCAACTACAACGTAATGCTCTCCCACTATTTCAATATGGGCGGCATTCGTAACATG
AGTATCTCTCTGACCGGTTATCGCTATGAGTATGACAACAGCGCCGATAAAGGTGTCTATATCTCCTTAAGTATGCCGTG
GGGTGATAGCAGTACGGTGAGTTACAACGGTAACTACGGTAGCGGTCCTGACAGCAGCCAGGTGGGGTATTTCAGCCGTA
TAGACGACGCCAGTCATTATCAGATAAACGTTGGCAACAGTGAAAATCACTCCAGCGTGGATGGTTATTACAGCCGTGAC
GGTTCAATGGCCCATGTGGACCTCAGTGCCAACTACCATGAAGGGCAGTACACCTCTGCCGGGTTGTCGCTACAGGGCGG
CGCCACGCTCACAGCTCACGGTGGTGCGTTGCACCGAACTCAAAATATGGGCGGTACGCGATTACTGATTGACGCTGACG
GTGTCGCCGACGTACCGGTCGAAGGGAATGGCGCAGCGGTTTATACCAATATGTTTGGCAAAGCCGTCGTTGCCGACGTC
AATAACTACTACCGTAACCAGGCCACTATTGACCTGACCAGACTGCCAGATGACGCTGAAGCCACGCAGTCTGTAGTGCA
GGCGACACTTACCGAAGGCGCCATTGGCTACCGTCAATTTGCGGTTATCAGTGGGCAAAAGGCGATGGCTGTCCTGCGCA
TGAGTGATGGCAGTTACCCGCCATTTGGTGCGGAAGTGAGAAACGAACACGACCAGCAGGTCGGCCTGGTTGATGATGAC
GGCAACGTCTATCTGGCTGGAGTAAAAGCGGGCGAACACATGTGTGTCTCATGGAATGGCGAACCCCACTGTGAGATCTC
ACTGCCAGACCCGCTACCTGCCGACCTGTTCAATGGCCTGTTACTGCCGTGCAAGCAACAAGGCGCTGTGCTGCCTGCGG
CTCCGGTAGAGATTAAACCGATGATTCAGGAACAAACGCAGCAGGTCACACCTGGCGCGGAACCCATGGCTATTTCAGCA
AACCAATAA

Protein sequence :
MDTCMPDHSLFRLRALPWCVAVAISGCHINAWADEDIQFDSRFLELKGDTKIDLKRFSSQGYVEPGKYSLQVEVNKQPLP
GEYDIYWYATENDANKTYACLSPDLAAQLGFKEDIANNLQWVLDGKCLKPGQLDGLEMRADLSQSALLITLPQAYLEYSD
VDWDPPSRWDDGISGLIADYSINAQTRHEENSGDDSNDISGNGTVGVNLGPWRLRADWQSDYQHTRSNDKETEDSTERNW
DWSRYYAWRALPSLKAKLALGEDYLDSDIFDGFNYIGGSISTDDQMLPPNLRGYAPDISGVAHTAAKVTVSQAGRIIYET
QVPAGPFRIQDLADFSSGTLHVRIEEVNGQVQEYDISTASMPFLTRPGQVRYKIMMGRPQEWGHHVQGGFFSGGEASWGI
ANGWSLYGGALGDENYQSAALGIGRDLSIFGAMAFDITHSHTRLDDSTAYGKSTLDGNSFRVSYSKDFDELNSRVTFAGY
RFSEENYMTMSEYLDANDSAMVRSGNDKEMYTATYNQNFRDAGVSVYLNYTRHTYWDREEQTNYNVMLSHYFNMGGIRNM
SISLTGYRYEYDNSADKGVYISLSMPWGDSSTVSYNGNYGSGPDSSQVGYFSRIDDASHYQINVGNSENHSSVDGYYSRD
GSMAHVDLSANYHEGQYTSAGLSLQGGATLTAHGGALHRTQNMGGTRLLIDADGVADVPVEGNGAAVYTNMFGKAVVADV
NNYYRNQATIDLTRLPDDAEATQSVVQATLTEGAIGYRQFAVISGQKAMAVLRMSDGSYPPFGAEVRNEHDQQVGLVDDD
GNVYLAGVKAGEHMCVSWNGEPHCEISLPDPLPADLFNGLLLPCKQQGAVLPAAPVEIKPMIQEQTQQVTPGAEPMAISA
NQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 1e-153 43
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 5e-152 43
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 6e-152 43
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 2e-153 43
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 1e-153 43
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 1e-153 43
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 4e-159 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EFER_0826 YP_002381999.1 outer membrane usher protein yfcU VFG1548 Protein 7e-154 43
EFER_0826 YP_002381999.1 outer membrane usher protein yfcU VFG0884 Protein 8e-154 43
EFER_0826 YP_002381999.1 outer membrane usher protein yfcU VFG0895 Protein 6e-154 43