Gene Information

Name : tktB (EFER_0714)
Accession : YP_002381893.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 732503 - 734506 bp
Length : 2004 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGTCCCGAAAAGACCTTGCCAATGCGATTCGCGCACTCAGTATGGATGCGGTGCAAAAAGCCAATTCCGGTCATCCCGG
CGCGCCGATGGGCATGGCAGATATTGCCGAAGTGCTGTGGAACGATTTTCTTAAACATAACCCCAGCGATCCAACCTGGT
ATGATCGCGACCGCTTTATTCTCTCCAACGGTCACGCGTCGATGCTGCTCTACAGTTTGCTTCATCTGACCGGTTACGAC
CTGCCGCTGGAAGAGCTGAAGAACTTCCGTCAGTTGCATTCGAAAACCCCAGGCCACCCGGAGATTGGCTATACACCAGG
TGTTGAAACCACCACCGGTCCACTTGGACAAGGTTTGGCTAACGCCGTCGGGCTGGCGATAGCAGAGCGTACACTGGCGG
CGCAGTTTAACCAGCCGGATCATGAGATCGTCGATCACTTCACCTATGTGTTTATGGGCGACGGCTGTCTGATGGAAGGT
ATCTCTCACGAAGTCTGTTCGCTGGCGGGCACACTGGGGCTGGGCAAACTGATTGGTTTTTACGATCACAACGGTATTTC
GATTGATGGAGAAACCGAAGGCTGGTTTACCGACGATACGGCAAAGCGTTTTGAAGCCTATCACTGGCATGTGATCCATG
AAATCGACGGCCACGATCCGCAGGCGGTGAAGGAAGCGATTCTTGAAGCGCAAAGCGTAAAAGATAAGCCATCGCTGATT
ATCTGCCGTACGGTGATTGGCTTTGGTTCACCGAATAAAGCAGGTAAGGAAGAGGCGCACGGCGCACCGCTTGGGGAAGA
AGAAGTGGCGCTGGCACGGCAAAAACTGGGCTGGCACCATCCGCCATTTGAGATCCCTAAAGAGATTTATCACGCCTGGG
ATGCCCGCGAAAAAGGCGAAAAAGCGCAGCAGAGCTGGAATGAGAAGTTTGCCGCCTATAAAAAGGCTCATCCGCAACTG
GCAGAAGAGTTTACCCGTCGGATGAGCGGTGGTTTACCGAAAGACTGGGAAAAAACGACACAGAAATATATCAATGAGTT
GCAGGCGAATCCGGCGAAAATCGCTACCCGTAAGGCTTCGCAAAATACGCTTAACGCTTACGGGCCAATGCTGCCTGAAC
TGCTTGGCGGTTCGGCGGATCTGGCCCCCAGCAATCTCACCATCTGGAAAGGTTCTGTGTCGCTGAAGGAAGATCCGGCG
GGTAACTACATTCACTACGGGGTGCGTGAATTTGGCATGACCGCTATCGCCAATGGCATTGCGCACCACGGCGGCTTCGT
GCCGTATACCGCGACGTTCCTGATGTTTGTTGAATACGCCCGTAACGCCGCGCGGATGGCAGCACTGATGAAAGCGCGGC
AGATAATGGTTTATACCCACGACTCTATTGGCTTAGGGGAAGATGGTCCGACGCACCAGGCCGTTGAGCAACTGGCCAGT
CTGCGCCTGACGCCGAATTTCAGCACCTGGCGACCGTGCGATCAGGTGGAAGCAGCGGTGGGCTGGAAGCTGGCGGTTGA
GCGCCACAATGGACCAACAGCACTGATCCTCTCAAGGCAGAATCTGGCACAGGTAGAACGAACGCCGGATCAGGTAAAAG
AGATTGCCCGTGGCGGTTATGTGCTGAAAGATAGCGGCGGTAAGCCAGATATTATTCTTATTGCTACCGGTTCAGAGATG
GAAATTACCCTGCAAGCAGCGGAGAAATTAGCGGGAGAAGGTCGCAATGTTCGCGTTGTTTCCCTGCCCTCGACGGATAT
TTTCGACGCTCAGGATGAGGAATATCGCGAGTCGGTACTGCCTTCTAATGTTTCAGCCCGCGTGGCGGTGGAAGCGGGTA
TTGCCGATTACTGGTACAAATATGTTGGTCTGAAAGGGGCAATTGTCGGGATGACCAGCTACGGGGAATCTGCCCCGGCG
GATAAACTGTTCCCATTCTTTGGCTTTACCCCCGAGAATATTGTGGCAAAAGCGCATAAGGTTCTGGGGGTTAAAAGCGC
CTGA

Protein sequence :
MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFLKHNPSDPTWYDRDRFILSNGHASMLLYSLLHLTGYD
LPLEELKNFRQLHSKTPGHPEIGYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGHDPQAVKEAILEAQSVKDKPSLI
ICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKLGWHHPPFEIPKEIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQL
AEEFTRRMSGGLPKDWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGSVSLKEDPA
GNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALMKARQIMVYTHDSIGLGEDGPTHQAVEQLAS
LRLTPNFSTWRPCDQVEAAVGWKLAVERHNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEM
EITLQAAEKLAGEGRNVRVVSLPSTDIFDAQDEEYRESVLPSNVSARVAVEAGIADYWYKYVGLKGAIVGMTSYGESAPA
DKLFPFFGFTPENIVAKAHKVLGVKSA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 74
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 66