Gene Information

Name : alr (EFER_4143)
Accession : YP_002385156.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 4243388 - 4244467 bp
Length : 1080 bp
Strand : +
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
ATGCAAGCGGCAACTGTTTTGATTAACCGCCGCGCTCTGCGACACAACCTGCAACGTCTGCGTGAACTGGCCCCCGCCAG
TAAACTGGTTGCGGTGGTGAAAGCGAACGCCTACGGTCACGGTCTGATTGAGACCGCGCGAACGCTCCCCGATGCTGACG
CCTTTGGCGTTGCCCGTCTCGAAGAAGCCCTACGGCTGCGAGCGGGGGGCATCACGCAACCTATTTTGTTACTGGAAGGT
TTTTTTGAAGCAGACGATTTGCCGACGATCTCCGCTGAACATCTGCAAACCGCAGTCCATAATGAAGAGCAGCTTGTCGC
CCTCGAAACCGCTGAGCTTAAAGAGCCTGTCATCGTCTGGATGAAGCTCGATACCGGAATGCACCGTCTGGGCGTATTGC
CGGAACAGGCCGAGGCGTTTTATCAGCGTCTGAGCCAGTGTAAAAATGTCCGCCAGCCGGTGAACATTGTCAGTCACTTC
GCCCGTGCCGATGAACCGCAAAGCGGCGCGACTGAAAAGCAGCTCGATATCTTCAACACCTTTTGTGAAGGTAAACCGGG
GCAACGCTCAATTGCGGCATCAGGCGGCATTTTGTTATGGCCGCAGTCGCATTTTGACTGGGCGCGTCCGGGGATCATTC
TTTACGGTGTTTCGCCGCTGGAAGATGGCACGACCGGGGCGGATTTTGGTTGTCAGCCAGTCATGTCTTTAACCTCCAGT
CTGATTGCCGTACGGGAGCATAAAGCCGGAGAGCCAGTAGGTTATGGCGGAACCTGGATTAGCGAACGTGATACCCGTCT
TGGTGTTGTGGCAATGGGCTATGGCGATGGTTATCCACGCGCTGCGCCGTCTGGTACTCCGGTACTGGTCAACGGTCGTG
AAGTGCCCATTGTCGGTCGGGTGGCAATGGATATGATCTGTGTGGATTTAGGTCCGCAGGCGCAAGATAAAGCCGGAGAT
CCGGTCATTCTGTGGGGTGAAGGGTTACCCGTTGAGCGTATCGCTGCAATGACAAAAGTAAGTGCTTACGAACTTATTAC
GCGCCTGACCTCAAGGGTAGCGATGAAATACGTGGATTAA

Protein sequence :
MQAATVLINRRALRHNLQRLRELAPASKLVAVVKANAYGHGLIETARTLPDADAFGVARLEEALRLRAGGITQPILLLEG
FFEADDLPTISAEHLQTAVHNEEQLVALETAELKEPVIVWMKLDTGMHRLGVLPEQAEAFYQRLSQCKNVRQPVNIVSHF
ARADEPQSGATEKQLDIFNTFCEGKPGQRSIAASGGILLWPQSHFDWARPGIILYGVSPLEDGTTGADFGCQPVMSLTSS
LIAVREHKAGEPVGYGGTWISERDTRLGVVAMGYGDGYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGD
PVILWGEGLPVERIAAMTKVSAYELITRLTSRVAMKYVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 6e-59 44