Gene Information

Name : nrdE (EFER_0395)
Accession : YP_002381599.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 408979 - 411123 bp
Length : 2145 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
TTGGCAACGACAACCGCAGAACGCCTGACGCAGGAAACAATGGATTACCACGCCCTGAATGCGATGCTTAACCTTTACGA
TAGCGCAGGTCGCATTCAGTTCGATAAAGATCGCCAGGCCGTTGACGCCTTTATGGCGACACATGTGCGTCCGAACAGTG
TGACCTTCAGTAGCCAGCAGCAGCGCCTGAACTGGCTGGTCAACGAAGGTTACTATGATGAAAACGTCCTCAACCGCTAC
TCTCGCGATTTTGTCATTACGCTGTTTGCCCACGCACACGCCAGCGGTTTTCGTTTTCAGACATTCCTCGGAGCATGGAA
GTTTTACACCAGCTATACGTTGAAGACATTCGACGGTAAGCGTTATCTGGAAGATTTTGCCGATCGAGTCACGATGGTGG
CGCTGACGCTGGCACAAGGCGATAAAACACTGGCTAAGCAACTGACCGATGAGATGCTGTCAGGACGCTTTCAGCCTGCA
ACACCGACATTCCTCAACTGCGGTAAGCGGCAGCGCGGCGAACTGGTTTCCTGTTTTTTGCTGCGTATTGAAGACAATAT
GGAGTCGATTGGCCGGGCAGTAAATTCCGCACTACAACTGTCGAAACGCGGCGGCGGCGTGGCATTTTTGCTGTCGAATC
TGCGGGAAGCGGGCGCGCCAATTAAACGTATTGAAAATCAATCTTCTGGCGTGATTCCGGTGATGAAAATGCTGGAGGAC
GCATTTTCCTATGCCAACCAGCTCGGCGCTCGTCAGGGTGCTGGCGCAGTCTATTTACATGCCCATCATCCCGATATTCT
GCGTTTTCTCGATACGAAACGGGAAAATGCCGACGAGAAAATCCGCATTAAAACACTGTCGCTGGGGGTGGTGATCCCGG
ATATCACCTTCCATCTGGCAAAAGAGAATGCGCAGATGGCGCTGTTTTCGCCCTATGACGTTGAGCGAGTTTATGGCAAG
CCGTTTGCCGATATCGCCATCAGCGAACACTATGCCGAACTGGTAGCCGATGAACGCATCCGCAAAAAATACATCAACGC
CCGTGATTTCTTCCAGCGGCTGGCGGAGATCCAGTTTGAATCCGGCTATCCCTACATCATGTATGAAGACACGGTTAACC
GTGCTAACCCTATTGCCGGGCGTATAAATATGAGCAATCTCTGCTCAGAAATTTTGCAGGTTAACAGCGCCTCAGAGTAT
GACGAGAATCTCGACTATGCCCGCACAGGCCATGATATTTCCTGCAATTTAGGTTCGTTGAATATTGCCCACACCATGGA
TTCCCCCGATTTTGCCCGCACGGTAGAGATCGCCGTGCGCGGTTTAACGGCAGTATCAGATATAAGTCATATCCGCAGCG
TGCCGTCCATCGAAGCCGGAAATGCCGCCTCGCACGCCATCGGACTGGGGCAGATGAATTTACACGGTTATCTGGCGCGA
GAAGGCATCGCTTATGGATCGCCGGAAGCACTCGATTTCACCAATCTCTATTTCTATACCATCACCTGGCACGCGCTGCG
TACCTCGATGTTACTGGCGCGCGAACGCGGCGAAACCTTTGCCGGGTTCAAACAGTCGCGCTATGCCAGCGGTGAATATT
TTAGCCAATATCTGCAAGGTAACTGGCAGCCGAAAACGGCGAAAGTTGGCGAGTTGTTTGCTCGTAGCAGTATCACGTTA
CCTACCCGCGAAATGTGGGCGCAACTGCGCGATGACGTAATGCGCTATGGCATTTACAACCAGAATCTCCAGGCAGTGCC
GCCAACTGGCTCCATCTCTTATATCAACCATGCCACGTCGAGCATTCATCCGATTGTGGCGAAAGTAGAGATACGCAAAG
AAGGCAAAACAGGACGCGTTTACTACCCTGCCCCGTTTATGACTAACGAAAATCTGGCGCTGTATCAGGACGCTTACGAA
ATCGGCGCAGAAAAGATCATCGACACCTACGCCGAAGCGGCTCGCCATGTCGATCAAGGGCTGTCGCTGACGCTGTTTTT
CCCTGATACCGCCACCACTCGCGATATCAACAAAGCGCAGATTTATGCCTGGCGTAAAGGTATCAAAACGCTCTACTACA
TCCGCCTGCGTCAGATGGCGCTGGAAGGTACTGAAATTGAAGGCTGCGTCTCCTGCGCGCTTTAA

Protein sequence :
MATTTAERLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAFMATHVRPNSVTFSSQQQRLNWLVNEGYYDENVLNRY
SRDFVITLFAHAHASGFRFQTFLGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDKTLAKQLTDEMLSGRFQPA
TPTFLNCGKRQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAGAPIKRIENQSSGVIPVMKMLED
AFSYANQLGARQGAGAVYLHAHHPDILRFLDTKRENADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGK
PFADIAISEHYAELVADERIRKKYINARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEILQVNSASEY
DENLDYARTGHDISCNLGSLNIAHTMDSPDFARTVEIAVRGLTAVSDISHIRSVPSIEAGNAASHAIGLGQMNLHGYLAR
EGIAYGSPEALDFTNLYFYTITWHALRTSMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKTAKVGELFARSSITL
PTREMWAQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPAPFMTNENLALYQDAYE
IGAEKIIDTYAEAARHVDQGLSLTLFFPDTATTRDINKAQIYAWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 72