Gene Information

Name : nrdF (EFER_0394)
Accession : YP_002381598.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit beta
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0208
EC number : 1.17.4.1
Position : 408010 - 408969 bp
Length : 960 bp
Strand : -
Note : B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE

DNA sequence :
ATGAAACTCTCACGTATCAGCGCCATCAACTGGAATAAGATATCTGACGATAAAGATCTGGAGGTGTGGAACCGCCTGAC
CAGCAATTTCTGGCTCCCGGAAAAGGTGCCGCTGTCGAACGATATTCCTGCGTGGCAGACATTAAGTGCCGCAGAACAAC
AACTGACGATGCGCGTTTTTACTGGCCTGACGCTGCTCGACACGCTGCAAAATGTTATCGGCGCGCCTTCACTGATGCCC
GATGCACTCACGCCCCATGAAGAGGCGGTATTATCAAATATCAGCTTTATGGAAGCGGTTCATGCCCGTTCTTACAGTTC
GATTTTCTCGACACTCTGCCAGACCAAAGATGTCGATGCCGCCTACACCTGGAGTGAGGAAAACGCGTCGTTGCAGCGAA
AAGCACAGATTATTCAGCAACATTATCGCGGTGATAATCCACTGAAAAAGAAAATCGCCAGTGTGTTTCTTGAATCATTT
TTGTTCTATTCTGGCTTCTGGCTGCCTATGTATTTTTCCAGTCGCGGAAAGCTAACCAATACCGCAGACCTGATCCGTCT
GATTATCCGCGATGAAGCAGTGCACGGTTATTACATCGGCTATAAATATCAGAAAAACCTTGAAAAGATCTCCCTGGCGC
AACGTGAAGAGTTGAAGAGTTTCGCCTTCGATTTGCTACTGGAACTTTACGACAACGAGTTGCAATACACCGATGAATTG
TACGCCGAAACCACATGGGCTGACGATGTGAAAGCGTTTCTCTGTTACAACGCCAATAAGGCGTTGATGAATCTGGGCTA
CGAACCGTTATTTCCCGCAGAAATGGCGGAAGTAAATCCGGCAATCCTCGCCGCGCTTTCGCCGAATGCCGATGAAAATC
ACGATTTCTTTTCTGGTTCAGGCTCCTCTTACGTGATGGGAAAAGCGGTCGAAACAGTAGATGAAGACTGGAATTTCTGA

Protein sequence :
MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPAWQTLSAAEQQLTMRVFTGLTLLDTLQNVIGAPSLMP
DALTPHEEAVLSNISFMEAVHARSYSSIFSTLCQTKDVDAAYTWSEENASLQRKAQIIQQHYRGDNPLKKKIASVFLESF
LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNLEKISLAQREELKSFAFDLLLELYDNELQYTDEL
YAETTWADDVKAFLCYNANKALMNLGYEPLFPAEMAEVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETVDEDWNF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1479 YP_001800873.1 ribonucleoside-diphosphate reductase subunit beta Not tested Not named Protein 9e-106 67