Gene Information

Name : thiC (EFER_3760)
Accession : YP_002384813.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 3853097 - 3854992 bp
Length : 1896 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGTCTGCAACAAAACTGACCCGCCGCGAACAACGCGCCCAGGCCCAACATTTTATCGACACCCTGGAAGGCACCGCCTT
TCCCAACTCAAAACGTATTTACATCACTGGCACACACCCCGGCGTGCGCGTGCCGATGCGTGAGATCCAGCTTAGCCCGA
CGCTAATTGGCGGCAGCAAAGAACAGCCGCAGTACGAAGAAAACGAAGCGATTCCGGTCTACGACACCTCCGGTCCGTAT
GGCGATCCACAGATCGCCATTAACGTGCAGCAAGGACTGGCAAAACTGCGCCAGCCGTGGATCGATGCGCGCGGCGATAC
CGAAGAACTTACCGTGCGCAGTTCCGATTACACTAAAGCGCGACTAGCAGATGATGGCCTCGACGAGCTACGTTTTAGCG
GCGTATTAACCCCAAAGCGCGCCAAAGCAGGACGCCGCGTCACCCAACTGCACTACGCCCGCCGGGGCATCATCACGCCC
GAAATGGAATTCATCGCCATTCGCGAGAATATGGGTCGCGAGCGCATACGTAGCGAAGTTTTGCGCCACCAGCATCCGGG
AATGAGCTTTGGCGCACGTCTGCCGGAAAATATCACCGCGGAATTTGTCCGTGATGAAGTTGCTGCCGGACGTGCGATTA
TCCCGGCCAACATTAATCATCCGGAATCGGAGCCGATGATTATTGGTCGCAACTTTCTGGTGAAGGTTAACGCCAATATC
GGCAACTCGGCAGTCACCTCTTCCATCGAAGAAGAAGTGGAAAAGCTGGTATGGTCTACGCGCTGGGGGGCGGATACAGT
GATGGATCTTTCCACCGGTCGCTATATTCACGAAACTCGCGAATGGATTTTGCGTAACAGCCCGGTGCCGATTGGTACAG
TGCCGATCTACCAGGCGCTGGAGAAGGTTAATGGGATCGCTGAAGATCTTACCTGGGAAGCGTTCCGGGACACGCTGCTG
GAACAGGCCGAGCAAGGTGTGGATTACTTCACTATCCATGCGGGCGTGCTACTTCGCTACGTGCCGATGACCGCGAAACG
CCTGACCGGTATCGTCTCTCGCGGCGGTTCGATTATGGCGAAATGGTGCCTCTCCCATCATCAGGAAAATTTCCTCTATC
AACACTTCCGCGAAATTTGTGAAATCTGTGCCGCTTATGATGTTTCGTTGTCGCTGGGCGACGGCCTGCGCCCCGGTTCT
ATTCAGGACGCCAACGATGAAGCGCAGTTTGCCGAGCTACATACGCTGGGCGAACTGACCAAAATCGCCTGGGAATATGA
CGTGCAGGTGATGATTGAAGGTCCTGGGCATGTACCGATGCAGATGATCCGCCGCAATATGACCGAGGAGTTAGAGCACT
GCCACGAAGCTCCGTTCTATACCCTCGGGCCGCTAACTACTGATATTGCGCCGGGTTATGACCACTTCACGTCGGGGATT
GGCGCGGCGATGATTGGCTGGTTTGGCTGCGCGATGCTCTGTTACGTAACGCCAAAAGAGCATCTGGGTCTACCTAATAA
AGAAGATGTTAAGCAGGGGCTTATCACCTATAAGATTGCCGCCCACGCCGCCGACCTGGCGAAAGGGCATCCGGGCGCGC
AAATTCGCGATAACGCCATGTCGAAAGCCCGCTTCGAATTTCGCTGGGAAGACCAGTTTAATCTGGCCCTCGACCCGTTT
ACCGCCCGCGCTTATCACGATGAAACCCTGCCGCAAGAGTCCGGCAAAGTCGCCCATTTTTGCTCCATGTGTGGGCCGAA
ATTCTGCTCGATGAAAATCAGCCAGGAAGTACGTGATTACGCCGCCGCGCAAACCATTGAAGTGGGAATGGCGGATATGT
CGGAGAACTTCCGTGCCAGAGGTGGAGAAATCTACCTGCGTAAGGAGGAAGCGTGA

Protein sequence :
MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGTHPGVRVPMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPY
GDPQIAINVQQGLAKLRQPWIDARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARRGIITP
EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANINHPESEPMIIGRNFLVKVNANI
GNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYIHETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLL
EQAEQGVDYFTIHAGVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSLGDGLRPGS
IQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEELEHCHEAPFYTLGPLTTDIAPGYDHFTSGI
GAAMIGWFGCAMLCYVTPKEHLGLPNKEDVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPF
TARAYHDETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEIYLRKEEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 69
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 69
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 68