Gene Information

Name : hemC (EFER_3700)
Accession : YP_002384764.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 3792455 - 3793396 bp
Length : 942 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAATGTTTTAAGAATTGCCACGCGGCAAAGCCCTCTTGCACTCTGGCAGGCACATTACGTTAAAGATGCGCT
GATGGCCAAACACCCTGGATTGACAGTGGAACTGGTGCCAATGGTCACTCGTGGCGATGTCATTCTGGATACACCGCTGG
CAAAAGTTGGCGGTAAAGGTTTATTCGTAAAAGAGCTTGAAGTCGCATTGCTGGAAAACCGTGCGGATATTGCTGTGCAT
TCGATGAAAGATGTGCCGGTCGAATTCCCACAAGGTCTGGGCCTGGTCACAATTTGTGAACGCGAAGATCCCCGCGATGC
GTTTGTTTCGAACAAATATGCCAGTCTGGATGAGCTGCCAGCAGGCAGTATCGTTGGAACGTCGAGTTTACGCCGTCAGT
GCCAGTTGGCGGAACGCCGCCCGGATCTGATTATCCGTTCACTGCGTGGCAATGTCGGTACACGCCTTAGTAAGCTGGAT
AACGGCGAATACGATGCCATTATTCTTGCCGTAGCCGGATTAAAACGTTTAGGGCTGGAATCACGCATTCGTGATGCGCT
GCCGCCTGAAGTATCACTACCCGCGGTAGGACAAGGTGCGGTAGGTATTGAGTGTCGCCTTGATGATACGCGCACCCGCG
AGCTACTCGCCGCGCTTAATCATCCTGAAACCGCGCTGCGTGTCACCGCCGAACGCGCTATGAACACCCGTCTTGAAGGT
GGTTGTCAGGTGCCGATTGGTAGCTATGCGGAGCTAATTGGCGGTGAGATTTGGTTAAGAGCATTGGTTGGCGCACCGGA
TGGTTCGCAGATGATTCGTGGTGAACGCCGTGGTTCGCCGCAGGACGCCGAAAAAATGGGTATTTCGCTGGCAGAAGAAC
TGCTCAATAACGGCGCACGGGCGATTCTCGCTGATGTATATAACGGAGATGCCCCCGTATGA

Protein sequence :
MLDNVLRIATRQSPLALWQAHYVKDALMAKHPGLTVELVPMVTRGDVILDTPLAKVGGKGLFVKELEVALLENRADIAVH
SMKDVPVEFPQGLGLVTICEREDPRDAFVSNKYASLDELPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
NGEYDAIILAVAGLKRLGLESRIRDALPPEVSLPAVGQGAVGIECRLDDTRTRELLAALNHPETALRVTAERAMNTRLEG
GCQVPIGSYAELIGGEIWLRALVGAPDGSQMIRGERRGSPQDAEKMGISLAEELLNNGARAILADVYNGDAPV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-85 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-85 61