Gene Information

Name : aldB (EFER_3582)
Accession : YP_002384657.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase B
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.22
Position : 3666130 - 3667668 bp
Length : 1539 bp
Strand : -
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 95286498, 7768815; Product type e : enzyme

DNA sequence :
ATGACCAACAATCCCCCTTCAGCACGTGTTCAGCCCGGCGAGTATGGTTTTCCTCTTAAGTTAAAAGCACGCTACGATAA
CTTTATCGGCGGCGAGTGGGTCGCGCCTGCCGACGGTGAGTATTACCAGAACCTGACGCCGGTGACCGGGCAGCTACTGT
GCGAAGTGGCGTCTTCGGGCAAACGTGACATCGATCTGGCGCTGGATGCTGCGCATAAAGTGAAAGATAAATGGGCGCAT
ACCTCGGTGCAGGATCGAGCGGCGATTCTGTTTAAGATTGCCGATCGGATGGAGCAGAACCTCGAGCTGTTAGCGACGGC
TGAAACCTGGGATAACGGCAAACCTATCCGCGAAACCAGTGCAGCCGATGTGCCGCTGGCGATTGACCATTTCCGCTATT
TTGCCTCGTGTATTCGGGCGCAGGAAGGCGGTATTAGTGAAGTGGATAGCGAAACCGTGGCTTACCACTTCCACGAACCG
TTAGGCGTGGTGGGGCAGATTATCCCCTGGAACTTCCCGCTGTTGATGGCGAGCTGGAAAATGGCCCCTGCGCTGGCGGC
GGGCAACTGCGTTGTGCTGAAACCCGCACGTCTTACCCCGCTTTCTGTACTGCTGCTAATGGAAATCGTCGGTGATTTAC
TGCCGCCGGGCGTGGTGAACGTGGTCAATGGCGCAGGTGGGGAAATTGGCGAATATCTGGCGACCTCGAAACGCATCGCC
AAAGTGGCGTTTACCGGCTCAACGGAAGTGGGCCAACAAATTATGCAGTACGCCACGCAAAATATTATTCCGGTAACCCT
GGAGCTGGGCGGCAAGTCGCCAAATATCTTCTTTGCTGATGTGATGGATGAAGAAGATGCCTTTTTCGATAAAGCGCTGG
AAGGCTTTGCACTGTTTGCTTTTAACCAGGGCGAAGTTTGCACCTGTCCAAGTCGTGCCTTAGTGCAGGAGTCTATCTAC
GAACGCTTTATGGAGCGCGCCATCCGCCGTGTCGAAAGCATTCGCAGCGGTAACCCGCTCGATAGCGTGACGCAAATGGG
GGCGCAAGTTTCGCACGGGCAACTGGAAACCATCCTCAACTACATTGATATCGGTAAAAAAGAGGGCGCAGACGTGCTCA
CCGGTGGGCGGCGCAAGCTGCTGGAAGGCGAACTGAAAGACGGCTACTACCTCGAACCGACGATTCTGTTTGGTCAGAAC
AATATGCGCGTGTTCCAGGAAGAAATTTTTGGTCCGGTGCTGGCGGTAACCACCTTCAAAACGATGGATGAGGCGCTGGA
GTTGGCGAACGACACGCAATATGGCCTGGGCGCAGGTGTCTGGAGCCGCAATGGTAACCTGGCCTATAAGATGGGGCGCG
GCATTCAGGCAGGGCGCGTGTGGACCAACTGTTATCACGCTTACCCGGCACATGCGGCGTTTGGTGGCTATAAGCAGTCG
GGTATCGGGCGCGAAACCCATAAGATGATGCTGGAGCATTACCAGCAAACCAAGTGCCTGCTGGTGAGCTACTCAGATAA
ACCGTTGGGTCTGTTCTGA

Protein sequence :
MTNNPPSARVQPGEYGFPLKLKARYDNFIGGEWVAPADGEYYQNLTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAH
TSVQDRAAILFKIADRMEQNLELLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGVVNVVNGAGGEIGEYLATSKRIA
KVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNIFFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIY
ERFMERAIRRVESIRSGNPLDSVTQMGAQVSHGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLEPTILFGQN
NMRVFQEEIFGPVLAVTTFKTMDEALELANDTQYGLGAGVWSRNGNLAYKMGRGIQAGRVWTNCYHAYPAHAAFGGYKQS
GIGRETHKMMLEHYQQTKCLLVSYSDKPLGLF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-145 64
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-150 63
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-150 63
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-150 63
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-149 63

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldB YP_002384657.1 aldehyde dehydrogenase B VFG0082 Protein 3e-145 64