Gene Information

Name : EFER_3533 (EFER_3533)
Accession : YP_002384609.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 3612957 - 3614168 bp
Length : 1212 bp
Strand : +
Note : Evidence 2b : Function of strongly homologous gene; PubMedId : 15901718; Product type e : enzyme

DNA sequence :
ATGACAGGTGAGCAGATGAACCACAATCAAAATTATGGAATGAATACCCGAATCGTCCATGCTGGGCAGCAGCCTGATCC
CTCAACAGGCGCTTTGAGTATGCCTATTTTTCAGACGTCTACTTTTGTCTTTGATAGTGCCGAACAAGGAGCTGCTCGTT
TTGCGCTGGAAGAGCCAGGCTACATTTATACGCGTTTAGGCAACCCAACAGTCGATGCCCTGGAGAAAAAACTCGCAGTA
TTAGAACAGGGAGAAGCGGCACTTGCGACTGCATCAGGAATTTCAGCAATTACCACAACGTTGCTGACTTTATGCCAGCA
AGGGGATCATATTATTTCCGCCAGTGCTATATACGGTTGTACTCATGCGTTTTTACAGCATAGCATTCCCAAATTTGGTA
TTAATGTCAGTTTTGTTAATGCCTCAAAACCAGAGGAAATTGTTGCAGCACTACGCCAGGAAACGAAAGTCATTTATATT
GAAACACCGGCTAATCCGACACTGTCTTTGGTGGATATTGCGGCTGTTGCTGATATTGCCCATCAAAGTGGGGTTATATT
AATTGTCGATAATACTTTTATGTCACCTTATTGCCAGCAGCCACTAACCCTGGGGGCAGATATTGTCATTCATAGTTTAA
CAAAATATATCAATGGTCATGGTGATGTTATTGGTGGTGTTATTATCGGCAAGCAGGAGTTTATCGATCAGGCTCGATTT
GTCGGTCTGAAGGATATTACCGGTGGATGCCTGAGTCCTTTCGACGCCTGGCTAACGTTACGTGGGGTAAAAACCCTGGG
AATACGTATGGAGCGCCATTGTCAGAATGCGTTGAGAATTGCCCATTACCTTGAGTCTCATCCGGCAATTACTCAGGTCT
GGTATCCGGGTCTACCTTCCCACCCACAATATATATTGGGCAAAAAACAGATGAGTCTTCCGGGAGGCGTAATCAGCTTT
GAAATCGCCGGAGGTCTTGAGACTGGCAGACGTATGATCAACTCTGTAGAATTATGCCTCCTCGCAGTCAGCCTCGGTGA
TACCGAAACCCTCATTCAGCATCCTGCGTCTATGACACATTCGCCTTTTGCACCAGAGGAACGGCTTGAAGCAGGTATTA
CCGATGGCCTTATTCGACTGTCAGTAGGTCTGGAGGATCCCGAAGATATCATTAACGACCTTGATCAAGCCATCAGAAAG
GCAACTCACTGA

Protein sequence :
MTGEQMNHNQNYGMNTRIVHAGQQPDPSTGALSMPIFQTSTFVFDSAEQGAARFALEEPGYIYTRLGNPTVDALEKKLAV
LEQGEAALATASGISAITTTLLTLCQQGDHIISASAIYGCTHAFLQHSIPKFGINVSFVNASKPEEIVAALRQETKVIYI
ETPANPTLSLVDIAAVADIAHQSGVILIVDNTFMSPYCQQPLTLGADIVIHSLTKYINGHGDVIGGVIIGKQEFIDQARF
VGLKDITGGCLSPFDAWLTLRGVKTLGIRMERHCQNALRIAHYLESHPAITQVWYPGLPSHPQYILGKKQMSLPGGVISF
EIAGGLETGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPFAPEERLEAGITDGLIRLSVGLEDPEDIINDLDQAIRK
ATH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-61 42
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-62 42
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-53 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EFER_3533 YP_002384609.1 methionine gamma-lyase BAC0207 Protein 2e-85 51