Gene Information

Name : arsB (EFER_3498)
Accession : YP_002384578.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Resistance
Product : arsenite/antimonite transporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1055
EC number : -
Position : 3574326 - 3575615 bp
Length : 1290 bp
Strand : +
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 15004242, 95355341, 1535622, 7721697; Product type t : transporter

DNA sequence :
ATGTTACTGGCGGGCGCTATCTTTGTCCTGACCATCGTATTGGTTATCTGGCAGCCGAAAGGTTTAGGCATCGGCTGGAG
TGCGACACTGGGCGCCGTACTGGCGTTAGTTACTGGCGTGGTCCATCCGGGCGATATTCCGGTGGTGTGGAATATCGTCT
GGAACGCGACGGCTGCGTTTATTGCCGTCATTATCATCAGCCTGCTGCTGGATGAGTCCGGCTTTTTTGAATGGGCGGCG
CTGCACGTCTCACGCTGGGGCAATGGGCGCGGTCGCTTGCTGTTTACCTGGATTGTCCTGCTCGGTGCTACCGTTGCGGC
CCTGTTTGCCAATGATGGCGCGGCGCTTATTTTGACGCCGATTGTCATCGCCATGCTGCTGGCTTTAGGGTTCAGCAAAG
GCACTACGCTGGCGTTTGTTATGGCGGCCGGATTCATTGCCGATACCGCCAGCCTGCCGCTTATTGTCTCCAATCTGGTG
AATATCGTTTCAGCAGATTTCTTTGACCTCGGCTTTCGCGAATATGCCTCGGTGATGGTGCCGGTGGATATCGCCGCGAT
TGTTGCCACGCTGGTGATGCTGCATCTCTTTTTTCGCAAAGATATTCCGCAGAACTACGACATGGCGCTGCTAAAATCTC
CCGCAGATGCGATTAAAGATCCTGCGACGTTCAAAACTGGCTGGGTTGTTTTACTGCTTCTGCTGGTGGGATTTTTCGTC
CTGGAACCGCTCGGCATTCCGGTAAGCGCTATTGCGGCAGTAGGCGCGCTGATATTATTTGCCGTCGCTAAACGCGGTCA
TGCGATTAATACGGGTAAAGTGCTGCGCGGTGCCCCCTGGCAGATTGTCATCTTCTCGCTCGGCATGTATCTGGTGGTTT
ACGGCCTGCGCAATGCCGGACTAACGGAATATCTTTCTGACGTACTCAACGTGCTGGCGGATAACGGCCTGTGGGCCGCG
ACGCTCGGTACCGGATTCCTCACCGCCTTCCTCTCTTCTATTATGAACAATATGCCGACGGTACTGGTTGGCGCGTTGTC
CATTGATGGCAGCACGGCGTCTGGTGTCATCAAAGAGGCGATGGTTTATGCCAACGTGATTGGCTGCGATTTGGGGCCGA
AAATTACACCGATTGGTAGCCTGGCAACGCTGCTCTGGCTGCACGTACTTTCGCAGAAGAATATGACTATCAGCTGGGGA
TATTACTTCCGTACAGGGATTATCATGACCCTACCGGTGCTGTTTGTGACGCTCGCCGCGCTGGCGCTTCGTCTCTCTTT
CACATCGTAA

Protein sequence :
MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAA
LHVSRWGNGRGRLLFTWIVLLGATVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
NIVSADFFDLGFREYASVMVPVDIAAIVATLVMLHLFFRKDIPQNYDMALLKSPADAIKDPATFKTGWVVLLLLLVGFFV
LEPLGIPVSAIAAVGALILFAVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAGLTEYLSDVLNVLADNGLWAA
TLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWG
YYFRTGIIMTLPVLFVTLAALALRLSFTS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
arsB2 YP_001007633.1 arsenical pump membrane protein Not tested YAPI Protein 8e-167 93
arsB YP_005754065.1 arsenical pump membrane protein Not tested Type-XI SCCmec Protein 2e-103 60
arsB YP_252017.1 arsenical pump membrane protein Not tested SCCmec Protein 5e-104 59
SH0109 YP_252024.1 arsenical pump membrane protein Not tested SCCmec Protein 2e-107 59

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
arsB YP_002384578.1 arsenite/antimonite transporter BAC0578 Protein 2e-169 94
arsB YP_002384578.1 arsenite/antimonite transporter BAC0576 Protein 2e-168 94
arsB YP_002384578.1 arsenite/antimonite transporter BAC0031 Protein 4e-166 92
arsB YP_002384578.1 arsenite/antimonite transporter BAC0577 Protein 6e-164 90
arsB YP_002384578.1 arsenite/antimonite transporter BAC0575 Protein 1e-108 60
arsB YP_002384578.1 arsenite/antimonite transporter BAC0574 Protein 4e-105 60