Gene Information

Name : int (EFER_2806)
Accession : YP_002383909.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : Integrase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0582
EC number : -
Position : 2872100 - 2873269 bp
Length : 1170 bp
Strand : -
Note : Evidence 2b : Function of strongly homologous gene; Product type h : extrachromosomal origin

DNA sequence :
ATGAAGCTGACTGCTCGTCAGGTTGAAACTGCAAAACCTAAAGATAAGCCCTACAAACTCGCTGATGGTGGTGGTCTTTA
CCTGCTGGTTAATCCCAATGGCAAAAGATACTGGCGTCTCAAATACCGTTCACTAGGCAAAGAGAAGCTGCTCGCTATTG
GCGTTTACCCTGATGTTTCTTTAGCTGAAGCCAGAAGTAAGCGTGAGGATGCTAAAAGAACATTAGCTGTTGGCAATGAT
CCTTCTCTTGAACGAAAAATTGAGAAACTTAGCCGTCAACAGGACGCAGAAAACTCGTTTGAGGCTATCACGCGGGAGTG
GTATCAGCGTCGCTATGACCGCTGGTCTGTCTCCTACCGCGAAGAGATGCTAAGAACCTTTGAAAAGGATGTATTTCCTT
ATATCGGTCACCGGCCAATCAAAGATATCAAGCCGATGGAGCTGCTTGCTGTTCTTTCAAAGATAGAAGCACGAGGAGCA
ACTGAGAAGGTACGTAAGGTTCGTCAACGTTGTGGAGAAGTCTGGAAGTATGCCGTTGTGACTGGCAGAGCCGAGTACAA
TCCAGCACCTGATCTAGCCAGCGCCGTGACTCCACATGAGAAAGAACACTATGCTTTTTTAACCCAGGATGAATTACCAG
AGTTTCTTCGGACTCTGAATACCTATGCCGGTAGTGTGCTTGTTAAGATTGCGATGCAATTACTTATTTTGACTGGAGTA
AGGCCTGGGGAATTGAGGCAAGCGGAGTGGCAGGAGTTTGATTTTGAGCGGAAGGTTTGGAACGTGCCAGCAGAGCGCAT
GAAAATGCGCCGCCCTCATCTGGTTCCGTTATCAAGCCAGGCAATTGACCTACTTAATCAGCTTAAACCTATGACAGGTG
CAGGTGCGTTGCTGTTCCCTGGGCGTAATAATCCTAAGAAATCGATGAGTGATATGGCATTGATTGTGTTGGTTAGGCGT
ATCGGCTATGCCGGGCGCGTTACGGGGCACGGATTCCGCCACACGATGAGTACTATTTTGCATGAGCAGGGATTTAACTC
GGCCTGGATTGAGTTACAGCTGGCTCACGTCGATAAGAACTCAATTCGTGGGACATATAACCATGCTCAATATCTGGAGG
GGCGGAGGGAGATGATGCAGTGGTATGGAGATTTGATCATTAATAATTGA

Protein sequence :
MKLTARQVETAKPKDKPYKLADGGGLYLLVNPNGKRYWRLKYRSLGKEKLLAIGVYPDVSLAEARSKREDAKRTLAVGND
PSLERKIEKLSRQQDAENSFEAITREWYQRRYDRWSVSYREEMLRTFEKDVFPYIGHRPIKDIKPMELLAVLSKIEARGA
TEKVRKVRQRCGEVWKYAVVTGRAEYNPAPDLASAVTPHEKEHYAFLTQDELPEFLRTLNTYAGSVLVKIAMQLLILTGV
RPGELRQAEWQEFDFERKVWNVPAERMKMRRPHLVPLSSQAIDLLNQLKPMTGAGALLFPGRNNPKKSMSDMALIVLVRR
IGYAGRVTGHGFRHTMSTILHEQGFNSAWIELQLAHVDKNSIRGTYNHAQYLEGRREMMQWYGDLIINN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
int CAC39282.1 integrase Not tested LPA Protein 7e-130 65
aec33 AAW51716.1 Int Not tested AGI-3 Protein 3e-130 65
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 1e-124 64
ECs4534 NP_312561.1 integrase Not tested LEE Protein 2e-129 64
int AAC31482.1 CP4-like integrase Not tested LEE Protein 1e-129 64
int ACU09430.1 integrase Not tested LEE Protein 1e-129 64
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 2e-129 64
int AAD44730.1 Int Not tested SHI-2 Protein 3e-128 64
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 5e-128 64
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 6e-128 64
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 6e-128 64
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 3e-117 59
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 1e-75 44
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 7e-74 42
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 7e-74 42
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 4e-72 41
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 2e-74 41
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 1e-74 41
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 9e-75 41
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-74 41
int AAL51003.1 CP4-like integrase Not tested LEE Protein 2e-74 41
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 2e-74 41
int AAK16198.1 Int Not tested PAI-I AL862 Protein 5e-75 41
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 5e-75 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
int YP_002383909.1 Integrase VFG0783 Protein 8e-130 64
int YP_002383909.1 Integrase VFG0598 Protein 3e-128 64
int YP_002383909.1 Integrase VFG1693 Protein 8e-75 41