Gene Information

Name : thyA (EFER_2760)
Accession : YP_002383866.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 2824492 - 2825286 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTATTTAGAACTGATGCAAAAAGTGCTCGACGAAGGCACTCAGAAAAACGACCGTACCGGAACCGGAACGCT
TTCCATTTTTGGTCATCAGATGCGTTTTAACCTGCAGGAGGGATTCCCGCTGGTAACAACCAAACGGTGCCACCTGCGTT
CCATTATCCACGAACTGCTGTGGTTTTTGCAGGGTGATACCAACATTGCGTACCTGCATGAAAACAATGTCACTATCTGG
GATGAATGGGCCGACGAAAACGGCGATCTCGGTCCGGTGTATGGCAAACAATGGCGCGCCTGGCCAACGCCGGATGGTCG
TCATATTGACCAGATCACTACAGTACTGAACCAGCTGAAAAACGACCCGGATTCCCGCCGCATTATTGTTTCAGCCTGGA
ACGTAGGCGAACTGGATAAAATGGCACTGGCTCCATGCCATGCATTCTTCCAGTTTTATGTGGCAGACGGCAAACTCTCT
TGCCAGCTTTATCAGCGCTCCTGTGACGTCTTCCTCGGCCTGCCGTTTAACATTGCCAGCTATGCGTTACTGGTGCATAT
GATGGCGCAGCAGTGTGATCTGGAAGTGGGCGATTTTGTCTGGACGGGGGGCGACACGCACCTCTACAGCAACCACATGG
ATCAAACCCATCTGCAATTAAGCCGCGAGCCACGTTCTCTGCCGAAGTTGATTATCAAACGTAAACCTGAATCCATCTTC
GACTACCGTTTTGAAGACTTTGAGATTGAAGGCTACGATCCGCATCCGGGCATCAAAGCCCCTGTTGCGATTTAA

Protein sequence :
MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQEGFPLVTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIW
DEWADENGDLGPVYGKQWRAWPTPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHLQLSREPRSLPKLIIKRKPESIF
DYRFEDFEIEGYDPHPGIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-88 66