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Name : leuS (EFER_2464) Accession : YP_002383574.1 Strain : Escherichia fergusonii ATCC 35469 Genome accession: NC_011740 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 2527409 - 2529991 bp Length : 2583 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAAGAGCAATACCGCCCGGAAGAGATAGAATCCAAAGTACAGCTTCACTGGGATGAGAAGCGCACATTTGAAGTAAC AGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCTATGCTTCCCTATCCTTCTGGTCGACTACACATGGGCCACGTAC GTAACTACACCATCGGTGACGTGATCGCCCGTTACCAGCGCATGCTGGGCAAAAACGTTCTGCAGCCGATCGGCTGGGAC GCGTTTGGTCTGCCTGCGGAAGGCGCAGCGGTGAAAAATAACACCGCGCCAGCACCGTGGACGTACGACAACATCGCGTA CATGAAAAACCAGCTCAAAATGCTGGGCTTTGGTTATGACTGGAGCCGCGAGCTGGCAACCTGTACGCCGGAATACTACC GTTGGGAACAGAAATTCTTCACCGAGCTGTATAAAAAAGGCCTGGTATATAAGAAGACTTCTGCGGTCAACTGGTGCCCG AACGACCAGACCGTACTGGCGAACGAACAGGTTATCGACGGCTGCTGCTGGCGCTGCGATACCAAAGTTGAGCGTAAAGA GATCCCGCAGTGGTTTATCAAAATCACCGCTTACGCTGACGAGCTGCTCAACGATCTGGATAAACTGGATCACTGGCCAG ACACCGTTAAAACCATGCAGCGTAACTGGATCGGTCGTTCCGAAGGCGTGGAAATCACCTTCAACGTTAACGACTATGAC AACACGCTGACCGTTTACACTACCCGCCCGGACACCTTTATGGGTTGTACCTACCTGGCGGTAGCGGCAGGTCATCCGCT GGCACAAAAAGCGGCGGAAAATAATCCTGAACTGGCGGCCTTTATTGACGAATGCCGTAACACCAAAGTTGCAGAAGCTG AAATGGCAACGATGGAGAAAAAAGGCGTCGATACTGGCTTTAAAGCGGTTCATCCATTAACGGGCGAAGAAATTCCGGTT TGGGCAGCAAACTTCGTATTGATGGAATACGGCACCGGCGCAGTCATGGCGGTTCCGGGTCACGACCAGCGCGACTACGA GTTTGCCTCTAAATACGGCCTCAACATCAAGCCGGTTATCCTGGCAGCTGACGGCTCTGAGCCAGATCTTTCTCAGCAAG CCCTGACCGAAAAAGGCGTGCTGTTCAACTCTGGCGAGTTCAACGGTCTTGATCATGAAGCAGCCTTCAACGCCATCGCC GATAAACTGACTGCGATGGGTGTTGGCGAGCGTAAAGTGAACTACCGCCTGCGCGACTGGGGTGTTTCCCGTCAACGTTA CTGGGGCGCGCCAATTCCGATGGTGACGCTGGAAGACGGTACTGTAATGCCTACCCCGGACGACCAGCTGCCGGTGATCC TGCCAGAAGATGTGGTGATGGACGGCATTACCAGCCCAATCAAAGCTGATCCTGAGTGGGCGAAAACCACCGTTAACGGT ATGCCTGCGCTGCGTGAAACCGATACTTTCGACACCTTTATGGAGTCCTCCTGGTACTATGCGCGCTACACTTGCCCTGA GTACAAAGAAGGTATGCTGGATTCCGAAGCGGCCAACTACTGGCTGCCGGTGGATATATACATTGGTGGTATCGAACACG CCATTATGCACCTACTCTACTTCCGCTTCTTCCATAAACTGATGCGTGATGCAGGCATGGTGAACTCTGACGAACCAGCA AAACAGTTGCTGTGTCAGGGTATGGTGCTGGCGGATGCCTTCTACTATGTTGGCGAAAACGGCGAGCGTAACTGGGTTTC CCCAGTTGATGCTATCGTTGAACGTGACGAGAAAGGCCGTATCGTGAAAGCGAAAGACGCGGCAGGCCATGAACTGGTTT ATACCGGCATGAGCAAAATGTCCAAGTCGAAGAACAACGGTATCGACCCACAGGTGATGGTTGAACGTTACGGCGCGGAC ACCGTTCGTCTGTTTATGATGTTTGCTTCTCCGGCGGATATGACTCTCGAATGGCAGGAGTCTGGTGTGGAAGGGGCTAA CCGCTTCCTGAAACGTGTCTGGAAACTGGTTTACGAGCACACTGCAAAAGGTGATGTTGCAGCACTGAACGTCGACGCGT TGACTGAAGATCAGAAAGCACTGCGTCGCGATGTTCATAAAACTATCGCTAAAGTGACCGATGATATCGGCCGTCGTCAG ACCTTCAACACCGCGATTGCGGCAATTATGGAGCTGATGAACAAACTGGCGAAAGCACCGACCGATGGCGAGCAGGATCG CGCCCTGATGCAGGAAGCGCTGCTGGCGGTAGTCCGTATGCTTAACCCGTTCACCCCGCACATCTGCTTCACGCTGTGGC AGGAGCTGAAAGGCGAAGGCGATATCGACAACGCGCCGTGGCCGGTTGCAGACGAGAAAGCGATGGTAGAAGATTCCACC CTGGTGGTGGTGCAGGTTAACGGTAAAGTCCGTGCCAAAATCACTGTTCCGGTGGACGCAACGGAAGAACAGGTTCGCGA ACGTGCTGGCCAGGAACATCTGGTAGCAAAATATCTTGATGGCGTTACCGTGCGTAAAGTGATTTACGTACCGGGTAAAC TCCTCAATCTGGTCGTTGGCTAA Protein sequence : MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWD AFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEITFNVNDYD NTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNPELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPV WAANFVLMEYGTGAVMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDHEAAFNAIA DKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQLPVILPEDVVMDGITSPIKADPEWAKTTVNG MPALRETDTFDTFMESSWYYARYTCPEYKEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPA KQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQVMVERYGAD TVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQ TFNTAIAAIMELMNKLAKAPTDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVEDST LVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 8e-155 | 42 |
