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Name : wzc (EFER_2144) Accession : YP_002383266.1 Strain : Escherichia fergusonii ATCC 35469 Genome accession: NC_011740 Putative virulence/resistance : Unknown Product : tyrosine kinase Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG3206 EC number : 2.7.10.2 Position : 2174928 - 2177090 bp Length : 2163 bp Strand : - Note : Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) DNA sequence : ATGACAGAAAAAGTAAAACAACATGCCGCTCCGGTAACGGGCAGTGATGAAATCGATATTGGTCGCCTGGTCGGCACCGT CATTGAAGCGCGCTGGTGGGTAATTGGCATCACCGCCGTATTCGCCCTCTGTGCTGTGGTTTACACCTTCTTCGCTACGC CGATATACAGCGCCGACGCACTGGTACAAATCGAGCAAAGCAGCGGCAATTCGTTAGTGCAGGATATCGGCTCGGCGTTA GCCAACAAGCCGCCAGCATCGGACGCCGAGATCCAGTTGATTCGCTCGCGTCTGGTGCTCGGTAAAACGGTGGACGATCT CGACCTCGATATTGCTGTGAGCAAAAACACGTTCCCGATTTTCGGTGCGGGCTGGGATCGCCTGATGGGACGCCAGAACG AGACGGTGAAAGTGACCACCTTTAACCGCCCGAAAGAGATGGCGGATCAGGTGTTTACGCTTAATGTGCTTGATGACAAA AACTACACTTTGAGCAGCGACGGCGGCTTTAGCGCTCGTGGGCAAGCGGGTCAGATGCTGAAAAAAGAAGGCGTCACGCT GATGGTTGAAGCTATTCACGCCAGCCAGGGCAGTGAGTTTACCGTCACTAAATACTCCACGCTGGGGATGATCAATCAAC TGCAAAACAGCCTGACGGTAACAGAGAATGGCAAAGACGCTGGCGTACTGAGCCTGACTTATACCGGTGAAGATCGCGAA CAGATCCGCGACATTCTTAACAGTATCGCCCGTAACTATCAGGAACAAAATATTGAGCGCAAATCGGCGGAAGCGTCGAA AAGCCTCGCCTTCCTCGCGCAACAGTTACCAGAAGTACGCAGCCGCCTTGATGTTGCTGAAAACAAACTGAATGCCTTCC GTCAGGATAAAGATTCTGTTGATCTGCCGCTGGAAGCGAAAGCGGTGCTTGATTCAATGGTGAACATCGACGCGCAGTTG AACGAACTGACCTTTAAAGAGGCGGAAATCTCCAAGTTGTACACCAAAGCTCACCCGGCGTACCGCACGCTGCTGGAGAA ACGTCAGGCGCTGGAAGAAGAGAAAGCCAAACTTAACGGTCGCGTAACGGCGATGCCGAAGACTCAGCAGGAAATTGTGC GTCTGACGCGCGATGTCGAGTCTGGTCAGCAAGTCTATATGCAACTGCTGAATAAAGAGCAGGAGCTGAAAATCACCGAA GCCAGCACCGTCGGCGATGTGCGCATTGTTGACCCGGCAATCACCCAGCCTGGCGTGCTAAAACCGAAGAAAGGGCTGAT TATCCTCGGCGCAATTATCCTCGGCCTGATGCTCTCTATCGTGGGTGTGCTGCTGCGCTCGTTGTTTAATCGCGGCATCG AAAGCCCGCAGGTGCTGGAAGAACACGGCATCAGCGTCTATGCCAGCATCCCGCTGTCGGAATGGCAAAAAGCGCGCGAT AGCGTCAAAACCATCAAAGGGGTTAAACGCTATAAACAGAGCCAGCTACTGGCGGTGGGGAATCCAACCGATCTGGCGAT TGAAGCCATCCGCAGTCTGCGTACCAGTCTGCACTTCGCGATGATGCAGGCGCAGAACAATGTGTTGATGATGACCGGGG TTAGCCCGTCAATCGGTAAAACCTTTGTCTGCGCTAACCTGGCGGCGGTGATCAGTCAGACCAATAAACGGGTGTTGTTG ATCGACTGCGATATGCGCAAAGGCTACACCCACGAGCTGTTGGGCACCAATAACGTCAATGGCCTGTCGGAAATTCTGAT TGGTCAGGGCGATATTACTACCGCTGCTAAACCGACCTCTATTGCCAAATTTGACCTGATCCCGCGCGGCCAGGTGCCGC CAAATCCTTCTGAACTGTTGATGAGCGAACGCTTTACCGAACTGGTGAACTGGGCGAGTAAAAACTACGACCTGGTGTTG ATTGATACGCCGCCGATTCTGGCTGTGACCGATGCCGCAATTGTCGGGCGTCACGTCGGAACCACGTTAATGGTGGCGCG TTATGCGGTCAACACCTTGAAAGAAGTGGAAACCAGTCTGAGCCGCTTTGAGCAAAACGGAATTCCGGTGAAAGGGGTGA TTCTGAACTCTATCTTTCGCCGCGCCAGCGCGTATCAGGATTATGGCTATTACGAATACGAATATAAGTCGGACGCGAAA TAA Protein sequence : MTEKVKQHAAPVTGSDEIDIGRLVGTVIEARWWVIGITAVFALCAVVYTFFATPIYSADALVQIEQSSGNSLVQDIGSAL ANKPPASDAEIQLIRSRLVLGKTVDDLDLDIAVSKNTFPIFGAGWDRLMGRQNETVKVTTFNRPKEMADQVFTLNVLDDK NYTLSSDGGFSARGQAGQMLKKEGVTLMVEAIHASQGSEFTVTKYSTLGMINQLQNSLTVTENGKDAGVLSLTYTGEDRE QIRDILNSIARNYQEQNIERKSAEASKSLAFLAQQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQL NELTFKEAEISKLYTKAHPAYRTLLEKRQALEEEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKEQELKITE ASTVGDVRIVDPAITQPGVLKPKKGLIILGAIILGLMLSIVGVLLRSLFNRGIESPQVLEEHGISVYASIPLSEWQKARD SVKTIKGVKRYKQSQLLAVGNPTDLAIEAIRSLRTSLHFAMMQAQNNVLMMTGVSPSIGKTFVCANLAAVISQTNKRVLL IDCDMRKGYTHELLGTNNVNGLSEILIGQGDITTAAKPTSIAKFDLIPRGQVPPNPSELLMSERFTELVNWASKNYDLVL IDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQNGIPVKGVILNSIFRRASAYQDYGYYEYEYKSDAK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| orf41 | AAO18066.1 | Orf41 | Not tested | TTSS locus | Protein | 2e-155 | 48 |
