Gene Information

Name : ldcC (EFER_0209)
Accession : YP_002381432.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Virulence
Product : lysine decarboxylase 2
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG1982
EC number : 4.1.1.18
Position : 231143 - 233284 bp
Length : 2142 bp
Strand : +
Note : Evidence 1b : Function experimentally demonstrated in the studied species; PubMedId : 97480927, 98195734, 98357244, 9226257, 9723924; Product type e : enzyme

DNA sequence :
ATGAATATCATTGCCATTATGGGACCGCATGGCGTCTTTTATAAAGATGAGCCCATCAAAGAACTGGAGTCGGCGCTGGT
GGCGCAAGGTTTTCAGATTATCTGGCCACAAAACAGCGTTGATTTGCTGAAATTTATCGAACACAACCCACGAATATGCG
GCGTGATTTTTGACTGGGATGAATACAGTCTCGATTTATGTAGCGATATCAATCAACTTAATGAATATCTCCCGCTTTAT
GCCTTCATCAATACTCACTCGACGATGGATGTCAGCGTGCAGGATATGCGGATGGCGCTCTGGTTCTTTGAATATGCGCT
GGGGCAGGCAGAAGATATCGCCATTCGTATGCGTCAGTACACCAACGAATATCTCGATAACATTACCCCGCCATTCACTA
AAGCCTTGTTTACTTATGTCAAAGAGCGGAAGTACACCTTTTGTACGCCGGGGCATATGGGCGGCACCGCGTATCAGAAA
AGCCCGGTAGGCTGTCTGTTTTATGATTTTTTCGGCGGTAATACCCTCAAGGCGGACGTCTCTATTTCGGTAACCGAGCT
AGGTTCGTTGCTCGACCACACCGGGCCACATCTGGAAGCGGAAGAGTACATCGCACGGACTTTCGGCGCGGAACAGAGTT
ATATCGTCACCAACGGAACATCGACGTCGAACAAAATTGTGGGTATGTACGCCGCGCCATCCGGCAGTACGCTGTTAATT
GACCGCAATTGTCATAAATCGCTGGCGCATCTGTTGATGATGAACGATGTAGTACCGGTCTGGCTAAAACCAACACGTAA
TGCGTTGGGGATTTTGGGCGGGATCCCGCGACGAGAATTTACCCGCGACAGTATCGAAGAGAAAGTCGCTGCTACCACGC
AGGCACAATGGCCGGTTCATGCGGTGATCACCAACTCAACCTATGATGGCTTGCTCTACAACACCGACTGGATCAAACAG
ACGCTGGATGTCCCCTCGATCCACTTCGATTCCGCCTGGGTCCCGTATACTCATTTTCATCCGATCTATCAGGGCAAAAG
TGGTATGAGTGGCGATCGGGTGGCAGGAAAAGTTTTCTTCGAAACGCAATCGACCCACAAAATGCTGGCGGCGTTGTCGC
AGGCATCACTGATCCACATTAAAGGTGAGTACGACGAAGAGGCGTTTAATGAAGCCTTTATGATGCATACCACCACCTCG
CCCAGTTATCCCATTGTTGCTTCGGTTGAGACAGCGGCGGCGATGCTGCGTGGTAATCCGGGCAAACGGCTGATTAACCG
TTCAGTAGAACGAGCGCTGCATTTTCGCAAAGAGGTCCAGCGGCTGCGGGAAGAGTCTGACGGCTGGTTTTTCGATATCT
GGCAACCGCCGCAGGTGGATGAAGCCGAATGCTGGCCCGTTGCGCCTGGCGAACAGTGGCACGGCTTTAACGATGCGGAT
GCCGATCATATGTTTCTCGATCCGGTTAAAGTCACTATTTTGACACCGGGGATGGACGAGCAGGGCAATATGAGCGATGA
GGGGATCCCGGCGGCGCTGGTGGCAAAATTCCTCGACGAACGTGGGATCGTAGTAGAGAAAACCGGCCCTTATAACCTGC
TGTTTCTCTTTAGTATTGGCATCGATAAAACCAAAGCAATGGGATTATTGCGTGGGTTGACGGAATTTAAGCGCTCTTAC
GATCTCAACCTGCGGATCAAAAATATGCTGCCCGATCTCTATGCAGAAGATCCCGATTTTTATCGCAATATGCGTATTCA
GGATCTGGCGCAAGGGATCCATAAGCTGATTCGTAAACACGATCTTCCCGGTTTGATGTTGCGGGCATTTGATACTTTGC
CGGAGATGATCATGACGCCACATCAGGCATGGCAACGGCAGATTAAAGGCGAAGTAGAAACCATTGCGCTGGAACAACTG
GTCGGTAGGGTATCGGCAAATATGATCCTGCCTTATCCACCGGGCGTACCGCTGTTGATGCCTGGAGAAATGCTGACCAA
AGAGAGCCGCACAGTACTCGATTTTCTACTGATGCTTTGTTCCGTAGGGCAACATTACCCCGGCTTTGAAACGGATATTC
ACGGCGCGAAACAGGACGAAGATGGCGTTTACCGCGTACGAGTCCTAAAAATGGCGGGATAA

Protein sequence :
MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLKFIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLY
AFINTHSTMDVSVQDMRMALWFFEYALGQAEDIAIRMRQYTNEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTNGTSTSNKIVGMYAAPSGSTLLI
DRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIPRREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQ
TLDVPSIHFDSAWVPYTHFHPIYQGKSGMSGDRVAGKVFFETQSTHKMLAALSQASLIHIKGEYDEEAFNEAFMMHTTTS
PSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWFFDIWQPPQVDEAECWPVAPGEQWHGFNDAD
ADHMFLDPVKVTILTPGMDEQGNMSDEGIPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSY
DLNLRIKNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAWQRQIKGEVETIALEQL
VGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSVGQHYPGFETDIHGAKQDEDGVYRVRVLKMAG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA NP_756988.1 lysine decarboxylase, inducible Not tested PAI II CFT073 Protein 0.0 70
unnamed CAD66195.1 putative cadaverin decarboxylase Virulence PAI III 536 Protein 0.0 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ldcC YP_002381432.1 lysine decarboxylase 2 VFG1670 Protein 0.0 61