Gene Information

Name : EFER_1967 (EFER_1967)
Accession : YP_002383096.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp proteinase ATP-binding subunit
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2016057 - 2018783 bp
Length : 2727 bp
Strand : -
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : factor

DNA sequence :
ATGATTCAGATTGATTTAGCTGCACTGGTTAAGCGCCTTAACCCGTTCACCAAACAGGCGCTGGAAATGGCGGCTTCAGA
ATGCATGAGCCAGCAGTCGGCAGAAATTACCGTCAGCCATGTGCTTATTCAGATGCTCGCCATACCGCGAAGCGATCTGC
GGGTTATTACAGAGCAGGTGGACATTACCGTGGACACGCTACGCCAGTCGTTAACAGAGGAGCGCTATGCCACTGTACGA
ATGGCAGACGGCTACCCGGCATTTTCTCCGATGCTGGTTGAATGGCTGAAAGAGGGCTGGCTGCTGGCCTCCGCAGAGAT
GCAGCACAACGAACTGCGTGGCGGTGTACTGTTGCTGGCGCTTCTGCACTCGCCGTTGCGTTATGTTCCGCCCGCCGTTG
CCCGACTGCTGACCGGCATTAACCGCGACCGCCTGCAACAGGATTTTGCGCAGTGGACGCGCGAGTCAGCAGAAACCGCG
ATGCGGAATGCTGACGGTCAGACCATGAATACGATGGTGGATACAGGGGACAGCCTGCTTGCCCGCTACGCCAAAAACAT
GACCGCAGACGCCCGTAACGGCAGGCTTGACCCGGTACTGTGCCGCGACCACGAAATCGACCTGATGCTCGACATTCTCT
GCCGCCGCCGTAAAAACAATCCGGTAGTGGTGGGTGAAGCAGGCGTGGGTAAAAGCGCGCTGATTGAAGGGCTGGCGCTG
CGCATCGTGGCAGGCCAGGTGCCGGACAAGCTGAAAAACACCGATATCATGACCCTTGACCTGGGTGCATTACAGGCCGG
GGCATCGGTGAAGGGCGAATTCGAAAAACGCTTCAAGGGGCTGATGGCGGAGGTTATTTCCTCCCCGGTGCCGGTCATTC
TGTTTATCGACGAAGCACATACCCTGATTGGCGCGGGCAACCAGCAGGGTGGGCTGGATATCTCCAACCTGCTGAAACCA
GCGCTGGCGCGCGGCGAACTGAAAACCATCGCCGCCACCACATGGAGCGAATACAAAAAATACTTCGAGAAAGACGCCGC
CCTGTCGCGCCGCTTCCAGTTGGTGAAGGTCAGCGAACCCAACGCCGCCGAAGCCACCATTATTCTGCGCGGTCTGTCGG
CGGTCTATGAACAGTCTCACGGCGTGCTGATTGATGATGACGCCTTGCAGGCCGCTGCGACATTAAGTGAGCGTTATCTC
TCCGGGCGTCAGTTGCCGGACAAAGCCATTGATGTGCTGGATACCGCCTGCGCCCGCGTGGCCATCAACCTGTCATCGCC
GCCGAAGCAAATCTCGGTGCTGACCACTCTGAGCCACCAGCAGGAGGCGGAAATTCGCCAGCTTGAGCGCGAGCTTCGCA
TCGGGCTGCGTACCGACACCTCACGGATGACCGAGGTACTGGTGCAGTATGATGAAACACTGGCGGCGCTGGATGAACTG
GAAGCGGCCTGGCACCAGCAGCAGACGCTGGTACGGGAAATTATCGCGCTGCGCCAGCAGTTACTGGGCGTGGATGCCAT
GGAGGATACGCCGTCAGAGTCAGAACAGGATAATACCGATGCTGAATCGACTGATGATGCTGGCAGCACACAGCCTGAAG
AGACCGCTGAAACAGTTTCCCCGGTGCAGAGGCTGACCCAGCTCACCGCCGAACTGGACACCCTGCATAACGACCGGTTG
CTGGTTTCCCCGCATGTCGATAAAAAACAGATTGCGGCGGTGATTGCCGAATGGACTGGCGTTCCGCTTAACCGCCTGTC
GCAGAATGAAATGTCGGTCATCACCGACCTGCCGAAGTGGCTTGGTGACACCATCAAAGGACAGGACCTGGCGATTGCCA
GCCTGCATAAACACCTGCTGACTGCACGCGCCGACCTGCGCCGTCCGGGACGCCCGCTGGGCGCGTTCCTGCTGGCCGGC
CCCAGCGGCGTGGGTAAAACCGAAACCGTCCTGCAACTGGCAGAACTGCTCTACGGCGGTCGCCAGTATCTGACCACCAT
CAATATGTCCGAGTTCCAGGAGAAGCACACCGTCTCGCGGCTGATTGGTTCCCCTCCGGGCTATGTCGGGTATGGTGAAG
GCGGCGTGCTGACCGAAGCGATTCGCCAGAAACCTTATTCTGTGGTGTTGCTCGACGAAGTGGAAAAAGCGCACCCGGAT
GTGCTTAACCTGTTCTACCAGGCGTTCGACAAGGGCGAGATGGCAGACGGCGAAGGCCGCCTGATTGACTGTAAAAACAT
CGTCTTCTTCCTCACCTCCAACCTCGGCTATCAGGTGATTGTCGAACACGCCGGTGACCCAGAAACCATGCAGGAAGCCC
TGTATCCGGTGCTGGCGGACTTCTTTAAACCTGCCCTGCTGGCGCGTATGGAAGTGGTGCCGTACCTGCCGCTGTCGAAA
GAGACGCTCGCCACCATCATTGCCGGGAAACTCACCCGTCTGGATAACGTGCTGCGCAGCCGCTTTGGTGCAGAAGTGAT
TATTGAACCGGAAGTAACGGACGAAATCATGAGCCGCGTCACCCGCGCGGAAAACGGCGCGAGGATGCTCGAATCGGTCA
TCGACGGCGACATGCTGCCGCCGCTCTCCCTGCTGCTGTTGCAGAAAATGGCGGCCAACACGGCGATTGCCCGGATTCGT
CTGTCGGCGGCAGACGGTGCATTCACGGCAGACGTGGAAGATGCTCAGAACGACGAGTCCGTCACAGAGGATGAAGCTGT
TTTATGA

Protein sequence :
MIQIDLAALVKRLNPFTKQALEMAASECMSQQSAEITVSHVLIQMLAIPRSDLRVITEQVDITVDTLRQSLTEERYATVR
MADGYPAFSPMLVEWLKEGWLLASAEMQHNELRGGVLLLALLHSPLRYVPPAVARLLTGINRDRLQQDFAQWTRESAETA
MRNADGQTMNTMVDTGDSLLARYAKNMTADARNGRLDPVLCRDHEIDLMLDILCRRRKNNPVVVGEAGVGKSALIEGLAL
RIVAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEKRFKGLMAEVISSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKP
ALARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEPNAAEATIILRGLSAVYEQSHGVLIDDDALQAAATLSERYL
SGRQLPDKAIDVLDTACARVAINLSSPPKQISVLTTLSHQQEAEIRQLERELRIGLRTDTSRMTEVLVQYDETLAALDEL
EAAWHQQQTLVREIIALRQQLLGVDAMEDTPSESEQDNTDAESTDDAGSTQPEETAETVSPVQRLTQLTAELDTLHNDRL
LVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLPKWLGDTIKGQDLAIASLHKHLLTARADLRRPGRPLGAFLLAG
PSGVGKTETVLQLAELLYGGRQYLTTINMSEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPD
VLNLFYQAFDKGEMADGEGRLIDCKNIVFFLTSNLGYQVIVEHAGDPETMQEALYPVLADFFKPALLARMEVVPYLPLSK
ETLATIIAGKLTRLDNVLRSRFGAEVIIEPEVTDEIMSRVTRAENGARMLESVIDGDMLPPLSLLLLQKMAANTAIARIR
LSAADGAFTADVEDAQNDESVTEDEAVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 0.0 90
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 0.0 90
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-122 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EFER_1967 YP_002383096.1 ATP-dependent Clp proteinase ATP-binding subunit VFG2084 Protein 0.0 58
EFER_1967 YP_002383096.1 ATP-dependent Clp proteinase ATP-binding subunit VFG2076 Protein 1e-135 42