Gene Information

Name : fliP (EFER_1933)
Accession : YP_002383064.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : -
Position : 1984350 - 1985087 bp
Length : 738 bp
Strand : +
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence : 
ATGCGCCGTTTGTTAACGCTTATTCCCGCCATTTTATGGCTGGTGACGCCTTGCGCACTGGCGCAATTGCCCGGCCTTGT
CACCCAACCGTTGCCCGGTGGAGGACAAAGCTGGTCGTTACCGGTGCAGACGCTGGTGTTTATCACCTCGCTGACTTTTA
TTCCGGCCATTTTACTGATGATGACCAGCTTTACCCGCATCATCATCGTTTTTGGTTTGCTACGTAACGCCCTGGGAACG
CCGTCTGCACCACCAAACCAGGTGCTGCTGGGGCTGGCGTTATTTTTGACCTTTTTTATTATGTCGCCGGTAATCGACAA
AATTTACGTCGATGCATATCAGCCATTCAGTGAAGAGAAAATCTCCATGCAGGAAGCGCTGGAAAAAGGCGCTCAGCCGC
TGCGTGAGTTTATGTTGCGCCAGACACGCGAAGCCGATCTTGCGTTATTTGCCCGGCTGGCCAATACCGGGCCGATTCAG
GGACCGGAAGCCGTACCCATGCGTATTCTGCTGCCTGCTTATGTTACCAGTGAGCTGAAAACAGCATTCCAGATTGGTTT
CACTATTTTTATTCCATTTTTGATTATCGATCTGGTCATTGCCAGCGTGCTGATGGCGCTGGGGATGATGATGGTGCCAC
CGGCCACTATCGCTCTGCCGTTTAAACTGATGTTGTTTGTGCTGGTGGATGGCTGGCAGCTGCTGGTCGGTTCGCTGGCC
CAAAGCTTTTACAGTTAG

Protein sequence : 
MRRLLTLIPAILWLVTPCALAQLPGLVTQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGT
PSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLALFARLANTGPIQ
GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA
QSFYS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECs4583 NP_312610.1 type III secretion system protein Virulence LEE Protein 1e-29 44
escR AFO66317.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-28 43
escR AFO66400.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 1e-28 43
hrcR AAT96262.1 HrcR Virulence S-PAI Protein 8e-26 42
hrcR AAT96303.1 HrcR Virulence S-PAI Protein 8e-26 42
hrcR AAT96343.1 HrcR Virulence S-PAI Protein 8e-26 42
lscR AAO18040.1 LscR Virulence TTSS locus Protein 1e-30 42
escR AAC38369.1 EscR Virulence LEE Protein 2e-29 42
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 4e-30 42
escR AAK26700.1 EscR Virulence LEE Protein 3e-30 42
escR AAL57527.1 EscR Virulence LEE Protein 3e-30 42
escR CAC81847.1 EscR protein Virulence LEE II Protein 3e-30 42
escR CAI43889.1 EscR protein Virulence LEE Protein 3e-30 42
escR AAC31528.1 L0049 Virulence LEE Protein 3e-30 42
escR YP_003223490.1 T3SS structure protein EscR Virulence LEE Protein 4e-30 42
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 3e-30 42
escR YP_003232138.1 type III secretion system protein Virulence LEE Protein 4e-30 42
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 4e-30 42
hrcR AAT96146.1 HrcR Virulence T-PAI Protein 3e-22 41
hrcR AAT96200.1 HrcR Virulence T-PAI Protein 3e-22 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliP YP_002383064.1 flagellar biosynthesis protein FliP VFG2338 Protein 1e-91 85
fliP YP_002383064.1 flagellar biosynthesis protein FliP VFG2494 Protein 3e-75 68
fliP YP_002383064.1 flagellar biosynthesis protein FliP VFG1259 Protein 1e-64 64
fliP YP_002383064.1 flagellar biosynthesis protein FliP VFG2016 Protein 1e-59 56
fliP YP_002383064.1 flagellar biosynthesis protein FliP VFG0188 Protein 7e-34 42
fliP YP_002383064.1 flagellar biosynthesis protein FliP VFG0827 Protein 2e-30 42
fliP YP_002383064.1 flagellar biosynthesis protein FliP VFG0715 Protein 1e-29 42
fliP YP_002383064.1 flagellar biosynthesis protein FliP VFG0044 Protein 2e-33 41
fliP YP_002383064.1 flagellar biosynthesis protein FliP VFG0394 Protein 3e-31 41