Gene Information

Name : umuC (EFER_1919)
Accession : YP_002383050.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : DNA polymerase V subunit UmuC
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0389
EC number : -
Position : 1973225 - 1974493 bp
Length : 1269 bp
Strand : -
Note : binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization

DNA sequence :
ATGTTTGCCCTTTGTGACGTGAATTCGTTTTATGCCAGCTGCGAGGTCGTGTTTCGCCCGGATTTATGGGGAAAACCGGT
GGTTGTGCTTTCCAATAACGATGGTTGCGTCATTGCCCGCAGTGCAGAAGCAAAAGCACTCGGTGTCAAAATGGGGGAGC
CCTATTTTAAACAAAAGGATCTGTTTCATCGCAGTGGTGTGGTCTGTTTCAGCAGTAACTATGAACTCTATGCCGATATG
AGCAACCGGGTGATGTGTACGTTGGAGGAGTTGTCGCCCAGAGTCGAAATTTACAGTATCGATGAAGCATTTTGTGATTT
AACCGGTGTGCGTAACTGCCGGGATTTAACAGATTTTGGTCGTGAAATTCGCCAGACCCTTTTTCAGCGTACACATCTAA
CGGTTGGCGTCGGCATTGCACAAACCAAGACGCTGGCCAAACTCGCCAACCATGCGGCTAAAAAATGGCAAAGACAAACT
GGGGGCGTGGTGGATTTATCGAACCGCGAGCGTCAGCGCAAATTAATGGCGGTACTTCCGGTTGAGGAAGTCTGGGGGAT
TGGCCGACGCATCAGCAAAAAGCTGGAGGCGATGGGAATAAAAACCGTACTTGATCTCGCGGATACGGATATCCGCTTTA
TTCGAAAACACTTTAATGTGGTGCTTGAAAGAACAGTACGGGAGTTGCGTGGTGAACCTTGCCTGGAGCTGGAAGAATTT
GCGCCAGCAAAACAAGAGATCATCTGCTCGCGGTCGTTTGGCGAACGCGTAACCGACTATGAGGCGATGCGCCAGGCTAT
ATGCAGTTATGCCTCACGCGCGGCAGAAAAACTGCGTAGCGAGCACCAGTATTGCCGCTTTATCTCCACGTTTGTAAAAA
CATCGCCGTTTTCGCTTAATGAACCGTATTACAGCAATAGCGCTTCGGTGAAGCTGCTGACGCCCACTCAGGACAGCAGG
GATATTATTAAGGCGGCGATCCGATGCCTGGATGCAATATGGCAAGAGGAGCATCGCTACCAGAAAGCGGGGGTGATGTT
GGGGGATTTTTTTAGTCGTGGAGTGGCGCAACTGAATTTGTTTGATGACAACGCACCGCGCGCTGGTAGTGAGGAGTTGA
TGGCTGTGCTCGACATGCTCAATGCCAGGGAAGGTCGTGGCACGCTCTATTTTGCCGGGCAGGGCATCCAGCAAGAGTGG
AAGATGAAGCGTGGGATGTTGTCACCACGATATACAACACGAGCCTCGGATCTTCTTTGTGTAAGGTAA

Protein sequence :
MFALCDVNSFYASCEVVFRPDLWGKPVVVLSNNDGCVIARSAEAKALGVKMGEPYFKQKDLFHRSGVVCFSSNYELYADM
SNRVMCTLEELSPRVEIYSIDEAFCDLTGVRNCRDLTDFGREIRQTLFQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
GGVVDLSNRERQRKLMAVLPVEEVWGIGRRISKKLEAMGIKTVLDLADTDIRFIRKHFNVVLERTVRELRGEPCLELEEF
APAKQEIICSRSFGERVTDYEAMRQAICSYASRAAEKLRSEHQYCRFISTFVKTSPFSLNEPYYSNSASVKLLTPTQDSR
DIIKAAIRCLDAIWQEEHRYQKAGVMLGDFFSRGVAQLNLFDDNAPRAGSEELMAVLDMLNAREGRGTLYFAGQGIQQEW
KMKRGMLSPRYTTRASDLLCVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
umuC NP_807889.1 DNA polymerase V subunit UmuC Not tested SPI-7 Protein 5e-125 63
samB NP_458681.1 UV protection protein Not tested SPI-7 Protein 5e-125 63
rulB CAI36137.1 nucleotidyltransferase/DNA polymerase Not tested PPHGI-1 Protein 7e-89 50
unnamed ABR13403.1 DNA-directed DNA polymerase Not tested PAGI-5 Protein 1e-74 49