Gene Information

Name : cadB (EFER_1901)
Accession : YP_002383032.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Virulence
Product : lysine/cadaverine antiporter
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0531
EC number : -
Position : 1946319 - 1947653 bp
Length : 1335 bp
Strand : -
Note : antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein

DNA sequence :
ATGAGTTCTGCCAAGAAGATCGGGCTATTTGCCTGTACCGGTGTGGTTGCCGGTAATATGATGGGGAGCGGTATTGCATT
ATTACCTGCGAACCTCGCAAGTATCGGTGGTATTGCTATCTGGGGTTGGATTATCTCTATTATTGGTGCAATGTCGCTGG
CTTATGTATATGCCCGACTGGCAACCAAAAACCCGCAGCAAGGTGGCCCAATTGCTTATGCCGGGGAAATTTCTCCTGCA
TTTGGTTTCCAGACGGGTGTTCTTTATTACCATGCTAACTGGATTGGTAACCTGGCGATTGGTATTACCGCCGTGTCTTA
TCTTTCCACCTTCTTCCCGGTATTAAATGACCCGGTTCCGGCAGGTATTGCCTGTATTGCCATTGTTTGGGTATTTACCT
TTGTAAATATGCTCGGTGGTACCTGGGTAAGCCGTTTAACCACAATTGGTCTGGTACTGGTTCTTATTCCGGTAGTAATG
ACCGCTATTGTCGGCTGGCACTGGTTTGATTCTGCTACTTATGCAGCTAACTGGAATACTGCACAAACCACTGATGGTCA
TGCGATCATTAAAAGTATTCTGCTCTGCCTGTGGGCCTTCGTGGGTGTTGAATCCGCAGCGGTAAGTACTGGTATGGTTA
AAAACCCGAAACGTACTGTTCCGCTGGCAACCATGTTGGGTACTGGTTTAGCAGGTATTGTTTACATCGCTGCGACTCAG
GTGCTTTCCGGTATGTATCCGTCTTCTGTAATGGCAGGCTCCGGTGCTCCGTTTGCAATCAGTGCTTCTACTATCCTGGG
TAACTGGGCTGCGCCGATGGTTTCTGCATTCACCGCGTTTGCGTGCCTGACTTCTCTGGGCTCCTGGATGATGCTGGTAG
GTCAGGCAGGTGTGCGTGCCGCTAACGACGGTAACTTCCCGAAAGTTTATGGTGAAGTCGACAGCAACGGTATTCCGAAA
AAAGGTCTGCTGCTGGCTGCAGTGAAAATGACTGCCCTGATGATCCTTATCACTCTGATGAACTCTGCTGGTGGTAAAGC
ATCTGACCTGTTCGGTGAACTGACCGGTATCGCAGTACTGCTGACTATGCTGCCGTACTTCTACTCTTGCGTTGACCTGA
TTCGCTTCGAAGGCGTTAACATCCGCAACTTTGCCAGCCTGATCTGCTCTGTACTGGGTTGCGTGTTCTGCTTCATCGCG
CTGATGGGGGCAAGCTCCTTCGAACTGGCTGGTACCTTCATCGTCAGCCTGATTATCCTGATGTTCTACGCTCGCAAAAT
GCATGAGCGCCAGAGCCACTCAATGGATAACCACACAGCGTCTAACGCCCATTAA

Protein sequence :
MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWIISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPA
FGFQTGVLYYHANWIGNLAIGITAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVM
TAIVGWHWFDSATYAANWNTAQTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKRTVPLATMLGTGLAGIVYIAATQ
VLSGMYPSSVMAGSGAPFAISASTILGNWAAPMVSAFTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPK
KGLLLAAVKMTALMILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFASLICSVLGCVFCFIA
LMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadB NP_756989.1 lysine/cadaverine antiporter Not tested PAI II CFT073 Protein 0.0 99
cadB AAL67382.1 cadaverine/lysine antiporter Not tested PAI II CFT073 Protein 0.0 99
unnamed CAD66196.1 putative lysin/cadaverin transporter Virulence PAI III 536 Protein 2e-134 68

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadB YP_002383032.1 lysine/cadaverine antiporter VFG1671 Protein 1e-134 68