Gene Information

Name : cvrA (EFER_1764)
Accession : YP_002382903.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : potassium/proton antiporter
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG3263
EC number : -
Position : 1813286 - 1815019 bp
Length : 1734 bp
Strand : +
Note : the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli

DNA sequence :
TTGGATGCCACGACGATCATCAGTCTGTTTATTTTAGGGTCAGTGCTTGTTACCTGCAGTATTCTCCTCAGTTCGTTTTC
TTCACGTCTTGGCATTCCTATTCTGGTTATCTTTTTGGCGATCGGTATGCTCGCCGGGGTCGATGGTGTCGGCGGTATTC
CATTCGATAATTATCCCTTCGCTTATATGGTCAGCAACCTCGCACTGGCGGTCATTTTACTTGATGGCGGAATGCGTACC
CAGGCCAGCTCGTTTCGTGTTGCTCTCGGCCCGGCACTCTCCCTCGCGACCGTGGGTGTGCTGATCACCTCAGGCCTGAC
GGGCATGATGGCAGCCTGGTTATTTAATCTCGATTTGATCGAAGGATTATTAATTGGCGCAATTGTCGGTTCTACCGATG
CTGCGGCAGTGTTTTCGCTGCTTGGTGGTAAAGGGCTTAACGAACGTGTTGGATCTACACTGGAAATAGAATCTGGCAGT
AATGATCCGATGGCGGTGTTTTTAACCATTACGCTGATTGAAATGATCCAGCATCACGAAACAGGAGTCAGCTGGACCTT
TGCATTGGATATTCTGCAACAGTTCGGCCTGGGTATCCTGTTGGGTCTGGGAGGTGGCTATTTACTTCAGCAGATGATTA
ACCGTATCGCCCTGCCTGCCGGGCTTTATCCAATGCTGGCATTAAGCGGCGGTATCCTGATTTTTGCGCTGACTACAGCA
CTTGAAGGCAGTGGCATTCTGGCAGTTTATCTATGTGGTTTCCTGCTCGGCAACCGACCGATTCGCAACCGCTACGGGAT
ATTGCAAAACTTCGACGGTCTGGCGTGGCTGGCGCAAATCGCCATGTTCCTGGTGCTCGGTTTACTGGTTAATCCTTCTG
ATCTGCTACCGATTGCTATTCCAGCACTACTTCTTTCCGCGTGGATGATTTTCTTTGCCCGTCCACTGTCAGTCTTTGCC
GGACTTCTGCCTTTCCGCGGTTTTAATCTACGGGAACGTATTTTTATCAGTTGGGTCGGCTTACGCGGAGCTGTACCTAT
TATTCTTGCGGTCTTTCCGATGATGGCCGGCCTGGATAATTCTCGTCTGTTCTTTAATGTGGCCTTCTTTGTGGTCTTAA
TTTCACTGTTGTTTCAGGGAACGTCTCTCTCCTGGGCAGCAAAAAAAGCGAAAGTCGTGGTGCCTGCCGTTGGTTGGCCC
GTCTCCCGCGTTGGTCTGGATATTCACCCGGAAAACCCGTGGGAACAGTTTGTTTATCAATTGAGTGCCGATAAATGGTG
TGTCGGTGCAGCATTACGCGATCTGCATATGCCCAAAGACACACGAATAGCGGCACTGTTTCGCGACAACGTGCTGTTGC
ATCCCTCGGGCAGTACCCGCCTGCGTGAAGGTGATGTACTTTGTGTGATTGGTCGTGAACGCGATCTTCCGGCGCTGGGC
AAATTATTTAGTCAATCACCGCCTGTGGCCCTGGATCAGCGTTTCTTTGGTGATTTTATTCTTGAAGGGAGCGCCAAATT
TGCTGATGTGGCGATTATTTATGGCCTCGATGCGGGCACTGAATATCGTGATAAACAACAGACGCTGGGCGAGATTGTAC
AGCAACTACTCGGGGCCGCCCCGGTTGTGGGTGACCAGGTAGAATTCGCGGGGATGATTTGGACGGTTGCTGAAAAAGAG
GATAATCAGGTCATGAAAGTGGGCGTTCGTGTCGCCGATGAGATTGCCGAATAA

Protein sequence :
MDATTIISLFILGSVLVTCSILLSSFSSRLGIPILVIFLAIGMLAGVDGVGGIPFDNYPFAYMVSNLALAVILLDGGMRT
QASSFRVALGPALSLATVGVLITSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
NDPMAVFLTITLIEMIQHHETGVSWTFALDILQQFGLGILLGLGGGYLLQQMINRIALPAGLYPMLALSGGILIFALTTA
LEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAWLAQIAMFLVLGLLVNPSDLLPIAIPALLLSAWMIFFARPLSVFA
GLLPFRGFNLRERIFISWVGLRGAVPIILAVFPMMAGLDNSRLFFNVAFFVVLISLLFQGTSLSWAAKKAKVVVPAVGWP
VSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKDTRIAALFRDNVLLHPSGSTRLREGDVLCVIGRERDLPALG
KLFSQSPPVALDQRFFGDFILEGSAKFADVAIIYGLDAGTEYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKE
DNQVMKVGVRVADEIAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
f536 AAC61706.1 F536 Not tested PAI I CFT073 Protein 0.0 93
unnamed AAB61290.1 unknown Not tested PAI I CFT073 Protein 0.0 93