Gene Information

Name : marA (EFER_1544)
Accession : YP_002382690.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Resistance
Product : DNA-binding transcriptional activator MarA
Function : -
COG functional category : K : Transcription
COG ID : COG2207
EC number : -
Position : 1577555 - 1577986 bp
Length : 432 bp
Strand : -
Note : transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF

DNA sequence :
GTGTTTGCTCAAGAAAATACTGTCGTAATAATAAGAGGTATGACAATGTCCAGACGCAATAATGACGCTATCACCATTCA
TAGCATTTTGGACTGGATTGAAGATAACCTGGAATCCCCTCTGTCACTGGAAAAAGTGTCAGAACGTTCAGGTTACTCCA
AATGGCACCTGCAACGGATGTTTAAAAAAGAAACTGGTCACTCTCTGGGCCAATATATCCGTAGCCGCAAAATGACGGAA
ATTGCGCAAAAACTAAAAGAAAGTAACGAGCCAATATTATATCTGGCAGAACGTTATGGTTTTGAGTCGCAGCAAACATT
AACCCGTACATTTAAAAATTATTTTGATGTACCACCACATAAATATCGTATGACAAATATGCATGGGGAATCCCGTTATT
TGCATCCGATAAATCACTGTCGCATGTCCTGA

Protein sequence :
MFAQENTVVIIRGMTMSRRNNDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTE
IAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDVPPHKYRMTNMHGESRYLHPINHCRMS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetD AAL08447.1 putative transcriptional regulator TetD Not tested SRL Protein 3e-21 44
tetD AEA34665.1 tetracycline resistance protein D Not tested Not named Protein 3e-21 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
marA YP_002382690.1 DNA-binding transcriptional activator MarA NC_002695.1.917339.p Protein 5e-55 96
marA YP_002382690.1 DNA-binding transcriptional activator MarA CP000034.1.gene1596. Protein 8e-56 96
marA YP_002382690.1 DNA-binding transcriptional activator MarA BAC0560 Protein 5e-55 96
marA YP_002382690.1 DNA-binding transcriptional activator MarA CP001138.1.gene1637. Protein 1e-53 96
marA YP_002382690.1 DNA-binding transcriptional activator MarA CP000647.1.gene1624. Protein 5e-53 94
marA YP_002382690.1 DNA-binding transcriptional activator MarA CP001918.1.gene2033. Protein 1e-53 93
marA YP_002382690.1 DNA-binding transcriptional activator MarA NC_010558.1.6276025. Protein 1e-21 44
marA YP_002382690.1 DNA-binding transcriptional activator MarA CP001138.1.gene612.p Protein 7e-23 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
marA YP_002382690.1 DNA-binding transcriptional activator MarA VFG1038 Protein 1e-21 44