Gene Information

Name : pykF (EFER_1376)
Accession : YP_002382529.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 1412393 - 1413805 bp
Length : 1413 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence : 
ATGAAAAAGACGAAAATTGTTTGCACAATCGGCCCGAAAACCGAATCAGAAGAGATGTTAACCAAGATGCTCGACGCAGG
CATGAACGTCATGCGTCTGAACTTCTCTCACGGTGATTACGCAGAACATGGTCAGCGCATCCAGAACTTGCGCAACGTTA
TGAGCAAAACCGGCAAACAAGCAGCCATCCTGCTCGACACCAAAGGCCCGGAAATCCGTACCATCAAACTGGAAGGCGGT
AATGACGTTTCCCTGAAAGCAGGCCAGACCTTTACTTTCACTACTGATAAATCTGTGGTGGGTAACAATGAGATCGTTGC
AGTAACTTACGAAGGCCTGACTTCCGACCTGTCTGTTGGCAACACTGTTCTGGTCGATGATGGTCTGATTGGCATGGAAG
TTACCGCTATTGAAGGTAACAAAGTTATTTGTAAAGTGCTGAACAACGGCGATCTGGGCGAAAACAAAGGTGTGAACCTG
CCTGGTGTTTCCATTGCCCTGCCAGCACTGGCTGAAAAAGACAAACAGGATCTGATCTTCGGCTGCGAACAAGGCGTTGA
CTTTGTTGCTGCTTCCTTTATTCGTAAACGCTCCGACGTAGAAGAGATTCGCGCACACCTGAAAGCGCACGGCGGCGAAA
ACATCCAGATCATCTCCAAAATTGAAAACCAGGAAGGCCTGAACAACTTCGACGAAATCCTCGAAGCGTCTGACGGTATC
ATGGTTGCGCGTGGCGACCTGGGTGTTGAAATCCCGGTTGAAGAAGTTATCTTCGCTCAGAAGATGATGATCGAAAAATG
TATCCGTGCACGTAAAGTCGTTATTACTGCGACTCAAATGCTGGATTCCATGATCAAAAACCCACGACCAACCCGCGCAG
AAGCAGGTGACGTTGCTAACGCCATTCTGGATGGTACTGACGCAGTTATGCTGTCTGGTGAATCCGCAAAAGGCAAGTAT
CCGCTGGAAGCTGTTTCTATTATGGCGACCATTTGTGAACGTACTGATCGTGTAATGACCAGCCGTCTGGATTTCAACAA
CGACAGCCGTAAACTGCGTATCACTGAAGCAGTTTGCCGTGGTGCGGTTGAAACAGCAGAAAAACTGGATGCCCCGCTGA
TCGTTGTAGCGACCCAGGGCGGTAAATCTGCACGTGCGGTGCGCAAATACTTCCCGGATGCAACCATCCTGGCGCTGACC
ACCAACGAAAAAACTGCACATCAGCTGGTGCTGAGCAAAGGCGTTGTGCCACAGTTGGTGAAAGAAATCACCTCTACTGA
TGACTTCTACCGTCTGGGTAAAGAACTGGCTCTGCAGAGCGGTCTGGCTCAGAAAGGTGATGTTGTGGTCATGGTTTCTG
GCGCACTGGTCCCAAGCGGCACAACCAATACCGCATCTGTTCACGTACTGTAA

Protein sequence : 
MKKTKIVCTIGPKTESEEMLTKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSKTGKQAAILLDTKGPEIRTIKLEGG
NDVSLKAGQTFTFTTDKSVVGNNEIVAVTYEGLTSDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVEEIRAHLKAHGGENIQIISKIENQEGLNNFDEILEASDGI
MVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKY
PLEAVSIMATICERTDRVMTSRLDFNNDSRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALT
TNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAQKGDVVVMVSGALVPSGTTNTASVHVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 0.0 98
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 0.0 98
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 0.0 98
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 0.0 97

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_002382529.1 pyruvate kinase VFG0479 Protein 0.0 98