Gene Information

Name : topB (EFER_1302)
Accession : YP_002382459.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 1340956 - 1342938 bp
Length : 1983 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
GTGCCATGGTTGAGATTCGTTAAGTCGATGCGGTTGTTTATTGCCGAAAAACCGAGTCTGGCGCGCGCCATTGCTGATGT
CCTGCCCAAACCGCACCGGAAAGGCGATGGCTTTATCGAGTGCGGCAATGGTCAGGTGGTGACCTGGTGTATCGGTCACC
TGCTTGAGCAGGCGCAGCCAGACACCTACGACAGCCGCTATGCACGCTGGAATCTGACTGATCTCCCCATTGTCCCGGAA
AAGTGGCAATTACAGCCCCGACCCTCCGTGACCAAACAACTTAATGTCATCAAACGCTTCTTGCATGAAGCCAGCGAAAT
TGTTCATGCCGGAGACCCGGATCGTGAAGGGCAGTTGCTGGTTGATGAAGTGCTGGACTATCTGCAACTGGCACCGGAAA
AGCGCCAGCAGGTACAACGTTGCTTGATAAACGACCTGAACCCGCAGGCGGTTGAGCGGGCGATCGATCGTCTTCGATCC
AATAGCGAGTTTGTACCGCTGTGCGTTTCTGCGCTGGCGCGAGCACGAGCCGACTGGTTATACGGCATCAATATGACCCG
CGCGTACACCATTCTCGGTCGTAATGCGGGTTATCAGGGCGTGCTTTCCGTGGGACGCGTGCAGACGCCCGTGCTCGGGC
TGGTGGTGCGCCGCGATGAAGAGATTGAAAACTTCGTGGCGAAAGACTTCTTTGAAGTCAAAGCGCATATCGTGACGCCT
GCCGATGAGCGGTTTACCGCTATCTGGCAACCAAGCGAAGCGTGTGAACCGTACCAGGATGAAGAAGGGCGCTTGTTACA
TCGTCCGCTGGCGGAGCATGTAGTTAACCGCATCAGTGGTCAACCGGCTATTGTCACCAGCTATAACAATAAACGGGAAT
CAGAATCCGCGCCGCTGCCGTTTTCGCTTTCGGCGTTGCAGATTGAAGCGGCAAAACGCTTTGGTCTGAGCGCGCAGAAT
GTGCTTGATATTTGTCAGAAGCTGTACGAAACGCACAAGTTAATCACTTATCCGCGTTCCGATTGTCGCTATTTGCCAGA
AGAACATTTTGCCGGACGCCACGCGGTGATGAATGCTATCAGCGTCCATGCGCCGGATCTGTTGCCGCAACCAGTGGTAG
ATCCAGATATACGCAACCGCTGTTGGGATGACAAAAAGGTCGATGCGCACCACGCCATCATCCCGACCGCGAGGAGTTCT
GCCATCAACCTGACGGAAAACGAGGCGAAGGTCTATAACCTGATTGCTCGTCAGTATTTGATGCAGTTCTGTCCGGACGC
GGTGTTCCGCAAGTGTGTTATCGAACTGGAAATAGCCAAAGGCAAATTTGTCGCTAAAGCCCGTTTTCTAGCTGAAGCAG
GCTGGCGCACGCTGTTAGGCAGCAAAGAGCGCGATGAAGAAAACGACGGCACGCCACTGCCTGTGGTGGCGAAAGGCGAT
GAGTTGCTGTGTGAAAAAGGCGAAGTGGTAGAGCGGCAAACGCAGCCACCGCGTCATTTTACCGATGCAACACTGCTTTC
GGCGATGACCGGGATCGCGCGCTTTGTGCAGGACAAAGATCTGAAAAAGATCCTTCGTGCCACCGATGGTCTGGGGACAG
AAGCAACCCGTGCCGGGATTATTGAACTGTTGTTCAAGCGTGGCTTTCTGACCAAAAAAGGGCGCTATATCCACTCCACC
GACGCCGGAAAAGCGTTATTCCATTCGCTGCCAGAAATGGCTACGCGACCGGACATGACCGCGCACTGGGAATCGGTGCT
GACGCAAATCAGCGAAAAGCAGTGTCGCTATCAGGACTTTATGCAACCGTTGGTGGGGACGTTGTACCAGTTGATTGATC
AGGCCAAACGTACGCCGGTGCGGCAGTTTCGCTGCATAGTGGCTCCAGATGGCGGAGAAGGAAATAAAAAGACTTCATCA
CGTAAGCGAGCAGCGAAAAAAAGCCCGCCAGCAGATGAAGCTGGAAGCGGGGCGATAGCGTAA

Protein sequence :
MPWLRFVKSMRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDTYDSRYARWNLTDLPIVPE
KWQLQPRPSVTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRS
NSEFVPLCVSALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTP
ADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNNKRESESAPLPFSLSALQIEAAKRFGLSAQN
VLDICQKLYETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSS
AINLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGD
ELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHST
DAGKALFHSLPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRCIVAPDGGEGNKKTSS
RKRAAKKSPPADEAGSGAIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 1e-109 41