Gene Information

Name : murD (EFER_0110)
Accession : YP_002381336.1
Strain : Escherichia fergusonii ATCC 35469
Genome accession: NC_011740
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 119056 - 120372 bp
Length : 1317 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGCTGATTACCAGGGTAAAAATGTCGTCATTATCGGCCTGGGCCTTACCGGGCTTTCTTGCGTGGACTTTTTCCTCGC
TCGCGGTGTGACGCCGCGCGTCATGGATACGCGGATGACACCGCCTGGCCTGGATAAATTACCCGAAGCCGTAGAACGCC
ACACGGGCGGTCTTAATGACGAATGGCTGATGGCGGCTGATCTGATCGTCGCCAGTCCCGGCATTGCATTGGCGCATCCT
TCCTTAAGCGCTGCCGCCGATGCCGGAATCGAAATCGTTGGCGATATCGAGCTATTCTGCCGCGAAGCACAAGCACCGAT
TGTGGCGATCACCGGTTCTAATGGCAAAAGCACTGTCACCACACTAGTGGGTGAAATGGCGAAAGCGGCGGGCGTTAACG
TTGGCGTGGGTGGCAACATTGGCCTGCCCGCGTTGATGCTGTTGGATGCTGAGTGCGAACTGTACGTGCTCGAGCTGTCG
AGCTTCCAGCTGGAAACCACCTCCAGTTTACAGGCGGTGGCAGCGACCATTCTGAACGTGACAGAAGATCATATGGATCG
CTATCCATTTGGTTTACAGCAGTATCGTGCGGCAAAATTGCGCATTTATGAAAATGCGAAAGTTTGCGTGGTTAATGCTG
ACGATGCCTTAACAATGCCGATTCGTGGTGCGGATGAACGTTGCGTTAGCTTTGGTATCAATATGGGCGACTATCACCTG
AATCATCAGCAGGGTGAAACCTGGCTGCGGGTGAAAGGCGAGAAAGTGTTGAACGTGAAAGAGATGAAACTTTCCGGTCA
GCATAACTACACCAATGCGCTGGCGGCACTGGCGCTGGCAGACGCAGCTGGATTACCACGTGCCAGTAGCCTGAAAGCGT
TAACTACGTTCACTGGTCTACCGCATCGCTTTGAAGTGGTGCTGGAACATAACGGTGTGCGCTGGATTAACGATTCGAAA
GCCACTAACGTCGGCAGTACGGAAGCAGCGTTGAATGGCTTGCACGTAGACGGCACGCTGCATTTGTTGCTGGGCGGCGA
TGGTAAATCGGCGGACTTCAGCCCACTGGCGCATTACCTGAATGGTGATAACGTGCGTCTGTATTGTTTTGGTCGTGACG
GTGCGCAGCTGGCGGCGCTACGCCCGGAAGTGGCAGAACAAACTGAAACCATGGAACAGGCGATGCGCTTGCTGGCTCCG
CGTGTTCAACCAGGAGATATGGTTCTGCTCTCCCCGGCCTGTGCCAGCCTTGATCAGTTCAAGAACTTTGAACAACGAGG
CAATGAATTTGCCCGTCTGGCGAAGGAGTTAGGTTGA

Protein sequence :
MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGLDKLPEAVERHTGGLNDEWLMAADLIVASPGIALAHP
SLSAAADAGIEIVGDIELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDAECELYVLELS
SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALTMPIRGADERCVSFGINMGDYHL
NHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAALALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSK
ATNVGSTEAALNGLHVDGTLHLLLGGDGKSADFSPLAHYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETMEQAMRLLAP
RVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 9e-53 45
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 9e-53 45